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MIRAGE
mitochondrial antiviral signaling protein
Summary
- Gene Symbol
-
- MAVS
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative splicing
- Antiviral defense
- Host-virus interaction
- Innate immunity
- Isopeptide bond
- Methylation
- Mitochondrion outer membrane
- Palmitate
- Peroxisome
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Transmembrane helix
- Ubl conjugation
- Proteins
| UniProt | Protein Name |
|---|---|
| Q7Z434 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of chemokine (C-C motif) ligand 5 production | ||
| positive regulation of IP-10 production | ||
| antiviral innate immune response | ||
| regulation of peroxisome organization | ||
| positive regulation of NLRP3 inflammasome complex assembly |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
positive regulation of immune system process [inference]
regulation of immune effector process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
regulation of production of molecular mediator of immune response [inference]
positive regulation of gene expression [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
regulation of production of molecular mediator of immune response [inference]
positive regulation of gene expression [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
regulation of production of molecular mediator of immune response [inference]
positive regulation of gene expression [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
regulation of primary metabolic process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
positive regulation of immune system process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of cellular process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of response to stimulus [inference]
positive regulation of multicellular organismal process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of response to biotic stimulus [inference]
regulation of signal transduction [inference]
regulation of response to external stimulus [inference]
positive regulation of response to stimulus [inference]
regulation of immune response [inference]
regulation of response to cytokine stimulus [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
regulation of cytokine production [inference]
regulation of production of molecular mediator of immune response [inference]
positive regulation of gene expression [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of cellular process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular biosynthetic process [inference]
regulation of cellular localization [inference]
regulation of multicellular organismal process [inference]
regulation of cytokine production [inference]
positive regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| ubiquitin ligase complex | ||
| mitochondrion | ||
| mitochondrion | ||
| mitochondrial outer membrane | ||
| mitochondrial outer membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| RIG-I binding | ||
| identical protein binding | ||
| CARD domain binding | ||
| molecular adaptor activity | ||
| molecular condensate scaffold activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- mitochondrial antiviral-signaling protein
- Functional Category
-
- J: Translation, ribosomal structure and biogenesis
- K: Transcription
- O: Posttranslational modification, protein turnover, chaperones
| Gene Ontology |
|---|
| immune system process |
| InterPro |
|---|
| Caspase recruitment domain |
| Death-like domain superfamily |
