GlyCosmos Portal

Submissions

kelch like family member 42

Summary

Gene Symbol

KLHL42

Organism

Homo sapiens (human)

External Links

NCBI Gene

57542

PubChem

57542

Alliance of Genome Resources

HGNC:29252

Annotation

Keyword

Cytoskeleton
Kelch repeat
Mitosis
Phosphoprotein
Proteomics identification
Reference proteome
Repeat
Ubl conjugation pathway

Proteins

Displaying **all 3** entries
UniProt	Protein Name
B2RNT7
F5H523
Q9P2K6	Cullin-3-binding protein 9 Kelch domain-containing protein 5

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
protein polyubiquitination	IDA	19261606
protein polyubiquitination	IBA
regulation of microtubule-based process	IMP	19261606
regulation of microtubule-based process	IBA
proteasome-mediated ubiquitin-dependent protein catabolic process	IDA	19261606

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination [inference]

protein polyubiquitination

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination [inference]

protein polyubiquitination

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination [inference]

protein polyubiquitination

macromolecule modification [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination [inference]

protein polyubiquitination

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination [inference]

protein polyubiquitination

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

cellular process [inference]

cell division

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

regulation of microtubule-based process

Displaying **all 4** entries
GO Term	Evidence Code	PMID
spindle	IEA
cytosol	TAS
Cul3-RING ubiquitin ligase complex	IDA	19261606
Cul3-RING ubiquitin ligase complex	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

intracellular protein-containing complex [inference]

ubiquitin ligase complex [inference]

cullin-RING ubiquitin ligase complex [inference]

Cul3-RING ubiquitin ligase complex

catalytic complex [inference]

transferase complex [inference]

ubiquitin ligase complex [inference]

cullin-RING ubiquitin ligase complex [inference]

Cul3-RING ubiquitin ligase complex

cellular anatomical entity [inference]

cytosol

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

spindle

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

spindle

Displaying **all 2** entries
GO Term	Evidence Code	PMID
ubiquitin-protein transferase activity	IDA	19261606
protein binding	IPI	16189514 19261606 25416956 28514442 32296183 33961781

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

aminoacyltransferase activity [inference]

ubiquitin-like protein transferase activity [inference]

ubiquitin-protein transferase activity

catalytic activity, acting on a protein [inference]

ubiquitin-like protein transferase activity [inference]

ubiquitin-protein transferase activity

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

kelch like family member 42

Functional Category

E: Amino acid transport and metabolism
K: Transcription
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
proteasome-mediated ubiquitin-dependent protein catabolic process
protein polyubiquitination
regulation of microtubule-based process

Displaying **all 4** entries
InterPro
Kelch repeat type 1
Kelch-like protein 42, BTB and C-terminal Kelch domain
Kelch-type beta propeller
SKP1/BTB/POZ domain superfamily

Ortholog

Displaying entries **1 - 10** of 72 in total

1

2

3

4

5

…

Next ›

Last »
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus laevis	57542	Xenbase:XB-GENE-6487005
Mus musculus	232539		MOUSE48717
Pan troglodytes	465361		PANTR06221
Canis lupus familiaris	477659		CANLF10951
Rattus norvegicus	500367		RATNO31390
Danio rerio	567545		DANRE34688
Macaca mulatta	711593		MACMU04927
Bos taurus	781458		BOVIN30046
Equus caballus	100069196		HORSE36128
Taeniopygia guttata	100226914		TAEGU09606