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MIRAGE
potassium sodium-activated channel subfamily T member 1
Summary
- Gene Symbol
-
- KCNT1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Calcium
- Cell membrane
- Disease variant
- Epilepsy
- Glycoprotein
- Phosphoprotein
- Potassium channel
- Proteomics identification
- Reference proteome
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q5JUK3 |
|
| A0A6Q8PGM3 |
|
| A0A0R4J2E0 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein homotetramerization | ||
| potassium ion transmembrane transport | ||
| potassium ion transmembrane transport |
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane | ||
| plasma membrane |
| GO Term | Evidence Code | PMID |
|---|---|---|
| intracellular sodium-activated potassium channel activity | ||
| intracellular sodium-activated potassium channel activity | ||
| outward rectifier potassium channel activity | ||
| outward rectifier potassium channel activity | ||
| metal ion binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- potassium channel subfamily t
- Functional Category
-
- E: Amino acid transport and metabolism
- K: Transcription
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| intracellular sodium-activated potassium channel activity |
| monoatomic ion transport |
| outward rectifier potassium channel activity |
| potassium channel activity |
| InterPro |
|---|
| Calcium-activated potassium channel BK, alpha subunit |
| Calcium-activated potassium channel slowpoke-like |
| Potassium channel domain |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060686 | autosomal dominant nocturnal frontal lobe epilepsy 5 | |
| DOID:0080439 | developmental and epileptic encephalopathy 14 |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 57582 | Xenbase:XB-GENE-22063991 | ||
| 60444 | Xenbase:XB-GENE-22063991 | RATNO26490 | |
| 227632 | Xenbase:XB-GENE-22063991 | MOUSE35186 | |
| 304827 | FB:FBgn0261698 | ||
| 343450 | FB:FBgn0261698 | ||
| 464846 | PANTR45228 | ||
| 491258 | CANLF19281 | ||
| 563670 | DANRE35410 | ||
| 721830 | MACMU13221 | ||
| 100016518 | MONDO05275 |
