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DEAH-box helicase 37

Summary

Gene Symbol

DHX37

Organism

Homo sapiens (human)

External Links

NCBI Gene

57647

PubChem

57647

Alliance of Genome Resources

HGNC:17210

JoGo

DHX37

TogoVar

DHX37

Annotation

Keyword

3D-structure
Cytoplasm
Disease variant
Helicase
Intellectual disability
Membrane
Nucleus
Proteomics identification
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q8IY37	DEAH box protein 37

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	IBA
brain development	IMP	31256877
ribosome biogenesis	IDA	30582406
ribosome assembly	IDA	30582406
ribosomal small subunit biogenesis	IDA	34516797

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

maturation of SSU-rRNA [inference]

maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

maturation of SSU-rRNA [inference]

maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

ncRNA processing [inference]

rRNA processing [inference]

maturation of SSU-rRNA [inference]

maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

maturation of SSU-rRNA [inference]

maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

maturation of SSU-rRNA [inference]

maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

ncRNA processing [inference]

rRNA processing [inference]

maturation of SSU-rRNA [inference]

maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

maturation of SSU-rRNA [inference]

maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

maturation of SSU-rRNA [inference]

maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

ncRNA processing [inference]

rRNA processing [inference]

maturation of SSU-rRNA [inference]

maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

maturation of SSU-rRNA [inference]

maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

maturation of SSU-rRNA [inference]

maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

ncRNA processing [inference]

rRNA processing [inference]

maturation of SSU-rRNA [inference]

maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

maturation of SSU-rRNA [inference]

maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

maturation of SSU-rRNA [inference]

maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

ncRNA processing [inference]

rRNA processing [inference]

maturation of SSU-rRNA [inference]

maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

maturation of SSU-rRNA [inference]

maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

maturation of SSU-rRNA [inference]

maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

ncRNA processing [inference]

rRNA processing [inference]

maturation of SSU-rRNA [inference]

maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

maturation of SSU-rRNA [inference]

maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

maturation of SSU-rRNA [inference]

maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

ncRNA processing [inference]

rRNA processing [inference]

maturation of SSU-rRNA [inference]

maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

maturation of SSU-rRNA [inference]

maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

maturation of SSU-rRNA [inference]

maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

ncRNA processing [inference]

rRNA processing [inference]

maturation of SSU-rRNA [inference]

maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

maturation of SSU-rRNA [inference]

maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

maturation of SSU-rRNA [inference]

maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

ncRNA processing [inference]

rRNA processing [inference]

maturation of SSU-rRNA [inference]

maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

maturation of SSU-rRNA [inference]

maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

maturation of SSU-rRNA [inference]

maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

ncRNA processing [inference]

rRNA processing [inference]

maturation of SSU-rRNA [inference]

maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

organelle assembly [inference]

non-membrane-bounded organelle assembly [inference]

ribosome assembly

cellular component assembly [inference]

organelle assembly [inference]

non-membrane-bounded organelle assembly [inference]

ribosome assembly

cellular component biogenesis [inference]

ribonucleoprotein complex biogenesis [inference]

developmental process [inference]

anatomical structure development [inference]

animal organ development [inference]

brain development

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of developmental process [inference]

positive regulation of gonad development [inference]

positive regulation of male gonad development

positive regulation of multicellular organismal process [inference]

positive regulation of gonad development [inference]

positive regulation of male gonad development

positive regulation of reproductive process [inference]

positive regulation of gonad development [inference]

positive regulation of male gonad development

regulation of developmental process [inference]

positive regulation of developmental process [inference]

positive regulation of gonad development [inference]

positive regulation of male gonad development

regulation of gonad development [inference]

positive regulation of gonad development [inference]

positive regulation of male gonad development

regulation of male gonad development [inference]

positive regulation of male gonad development

regulation of multicellular organismal process [inference]

positive regulation of multicellular organismal process [inference]

positive regulation of gonad development [inference]

positive regulation of male gonad development

regulation of reproductive process [inference]

regulation of gonad development [inference]

positive regulation of gonad development [inference]

positive regulation of male gonad development

regulation of male gonad development [inference]

positive regulation of male gonad development

positive regulation of reproductive process [inference]

positive regulation of gonad development [inference]

positive regulation of male gonad development

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
nucleoplasm	TAS
nucleolus	IDA	31337883
nucleolus	IBA
cytoplasm	IDA	31337883
nuclear membrane	IDA	31337883

GO Hierarchy

cellular component

protein-containing complex [inference]

ribonucleoprotein complex [inference]

preribosome [inference]

small-subunit processome

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

nuclear membrane

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

nucleolus

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

nucleolus

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
DNA clamp loader activity
RNA binding	IBA
RNA helicase activity	IEA
helicase activity	IBA
protein binding	IPI	30582406

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

catalytic activity, acting on a protein [inference]

ATP-dependent histone chaperone activity [inference]

catalytic activity, acting on a nucleic acid [inference]

helicase activity

RNA helicase activity

catalytic activity, acting on DNA [inference]

ATP-dependent activity, acting on DNA [inference]

DNA clamp loader activity

DNA translocase activity [inference]

chromatin extrusion motor activity

ATP-dependent chromatin remodeler activity [inference]

ATP-dependent histone chaperone activity [inference]

cohesin loader activity

catalytic activity, acting on RNA [inference]

RNA helicase activity

binding [inference]

protein binding

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding

snoRNA binding [inference]

U3 snoRNA binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

molecular carrier activity [inference]

protein carrier chaperone [inference]

histone chaperone activity [inference]

H3-H4 histone complex chaperone activity [inference]

ATP-dependent H3-H4 histone complex chaperone activity

ATP-dependent histone chaperone activity [inference]

ATP-dependent activity [inference]

helicase activity

RNA helicase activity

ATP-dependent activity, acting on DNA [inference]

DNA clamp loader activity

DNA translocase activity [inference]

chromatin extrusion motor activity

ATP-dependent chromatin remodeler activity [inference]

ATP-dependent histone chaperone activity [inference]

ATP-dependent activity, acting on RNA [inference]

RNA helicase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

helicase

Functional Category

C: Energy production and conversion
J: Translation, ribosomal structure and biogenesis
L: Replication, recombination and repair

Displaying **all 3** entries
Gene Ontology
ATP binding
hydrolase activity
nucleotide binding

Displaying **all 8** entries
InterPro
DEAD-box helicase, OB fold
DEAD/DEAH box helicase domain
DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site
Helicase associated domain (HA2), winged-helix domain
Helicase superfamily 1/2, ATP-binding domain
Helicase, C-terminal domain-like
Helicase-associated domain
P-loop containing nucleoside triphosphate hydrolase