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Guidelines

MIRAGE

protein tyrosine phosphatase non-receptor type 4

Summary

Gene Symbol

PTPN4

Organism

Homo sapiens (human)

External Links

NCBI Gene

5775

PubChem

5775

Alliance of Genome Resources

HGNC:9656

JoGo

PTPN4

TogoVar

PTPN4

Annotation

Keyword

3D-structure
Cell membrane
Cytoskeleton
Phosphoprotein
Protein phosphatase
Proteomics identification
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
P29074	Protein-tyrosine phosphatase MEG1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
chromatin remodeling	IEA
protein dephosphorylation	TAS	1648233

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation [inference]

protein dephosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein dephosphorylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein dephosphorylation

cellular process [inference]

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

dephosphorylation [inference]

protein dephosphorylation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

protein-containing complex organization [inference]

protein-DNA complex organization [inference]

chromatin organization [inference]

chromatin remodeling

Displaying entries **1 - 5** of 7 in total

1

2

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GO Term	Evidence Code	PMID
nucleoplasm	TAS
cytoplasm	IDA	10940933
cytoplasm	IBA
cytosol	TAS
cytoskeleton	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton

side of membrane [inference]

cytoplasmic side of membrane [inference]

cytoplasmic side of plasma membrane

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
protein tyrosine phosphatase activity	IBA
non-membrane spanning protein tyrosine phosphatase activity	IEA
protein binding	IPI	16169070 17474147 21988832 25158884 32814053
cytoskeletal protein binding	IEA
protein tyrosine phosphatase activity, metal-dependent	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on ester bonds [inference]

phosphoric ester hydrolase activity [inference]

phosphatase activity [inference]

phosphoprotein phosphatase activity [inference]

protein tyrosine phosphatase activity

histone phosphatase activity [inference]

histone H2AXY142 phosphatase activity

catalytic activity, acting on a protein [inference]

phosphoprotein phosphatase activity [inference]

protein tyrosine phosphatase activity

histone phosphatase activity [inference]

histone H2AXY142 phosphatase activity

histone modifying activity [inference]

histone phosphatase activity [inference]

histone H2AXY142 phosphatase activity

binding [inference]

protein binding

signaling receptor binding [inference]

glutamate receptor binding

cytoskeletal protein binding

Gene Ontology information from NCBI Gene and UniProt.

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.5.0

Last updated: April 6, 2026