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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
WD repeat domain 4
Summary
- Gene Symbol
-
- Wdr4
- Organism
- Mus musculus (house mouse)
Annotation
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| tRNA (guanine-N7)-methylation | ||
| tRNA modification | ||
| DNA damage response | ||
| cellular response to DNA damage stimulus |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| tRNA (m7G46) methyltransferase complex | ||
| nucleoplasm | ||
| tRNA methyltransferase complex | ||
| nucleus | ||
| cytosol |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| enzyme activator activity | ||
| tRNA methyltransferase activator activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit
- Functional Category
-
- J: Translation, ribosomal structure and biogenesis
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| RNA (guanine-N7)-methylation |
| tRNA methylation |
| tRNA processing |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050569 | Seckel syndrome | |
| DOID:0080694 | Galloway-Mowat syndrome | |
| DOID:0081051 | microcephaly, growth deficiency, seizures, and brain malformations |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 10785 | HGNC:12756 | HUMAN58800 | ||
| 31566 | FB:FBgn0029857 | |||
| 190860 | WB:WBGene00022420 | |||
| 458584 | PANTR25755 | |||
| 487783 | CANLF12906 | |||
| 548387 | Xenbase:XB-GENE-6454934 | |||
| 570351 | ZFIN:ZDB-GENE-060810-10 | DANRE44466 | ||
| 690032 | 10116_1:00523d | RGD:1585179 | RATNO22224 | |
| 714230 | MACMU31623 | |||
| 851743 | SGD:S000002572 |
