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Standards Ontologies Notations
glucose-6-phosphatase catalytic subunit 2

Summary
Gene Symbol
  • G6PC2
Aliases
  • IGRP
  • islet specific glucose 6 phosphatase catalytic subunit related protein
Organism
Homo sapiens (human)
External Links
NCBI Gene
57818
HGNC
28906
KEGG Gene ID
hsa:57818
PubChem
57818
Alliance of Genome Resources
Annotation
Keyword
  • Alternative splicing
  • Endoplasmic reticulum
  • Gluconeogenesis
  • Glycoprotein
  • Hydrolase
  • Reference proteome
  • Transmembrane helix
Proteins
Displaying 1 entry
UniProt Protein Name
Q9NQR9
  • Islet-specific glucose-6-phosphatase catalytic subunit-related protein
Annotation information from UniProt.
Gene Ontology (GO)
Displaying all 4 entries
GO Term Evidence Code PMID
regulation of insulin secretion
glucose 6-phosphate metabolic process
glucose homeostasis
gluconeogenesis
GO Hierarchy
Gene Ontology information from NCBI Gene and UniProt.
KEGG BRITE Database
Orthology
K01084
Name
glucose-6-phosphatase [EC:3.1.3.9]
References
Rhea

RHEA:16689

H2O + D-glucose 6-phosphate
D-glucose + phosphate
Enzyme
PMID

RHEA:44904

H2O + α-D-glucose 6-phosphate
α-D-glucose + phosphate
Enzyme
Disease
Disease Ontology
Displaying entries 1 - 10 of 44 in total
DO ID Disease Name Source
DOID:0050782 Zollinger-Ellison syndrome
DOID:0110741 type 1 diabetes mellitus 2
DOID:0110742 type 1 diabetes mellitus 3
DOID:0110743 type 1 diabetes mellitus 4
DOID:0110744 type 1 diabetes mellitus 5
DOID:0110745 type 1 diabetes mellitus 6
DOID:0110746 type 1 diabetes mellitus 7
DOID:0110747 type 1 diabetes mellitus 8
DOID:0110748 obsolete type 1 diabetes mellitus 9
DOID:0110749 type 1 diabetes mellitus 10
Ortholog
Displaying entries 31 - 40 of 79 in total
Species Gene ID Alliance of Genome Resources Orthologous MAtrix
122228509 PANLE09856
101339386 TURTR14318
118898470 BALMU00309
100670402 LOXAF18980
100062750 HORSE13923
505012 BOVIN24131
102174704 CAPHI20939
101121493 SHEEP09444
100345755 RABIT11745
105995068 DIPOR00670
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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024