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MIRAGE
BCL2 associated X, apoptosis regulator
Summary
- Gene Symbol
-
- BAX
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Acetylation
- Alternative splicing
- Apoptosis
- Cytoplasm
- Host-virus interaction
- Isopeptide bond
- Mitochondrion outer membrane
- Nucleus
- Proteomics identification
- Reference proteome
- Transmembrane helix
- Tumor suppressor
- Ubl conjugation
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| apoptotic process | ||
| apoptotic process | ||
| apoptotic process | ||
| germ cell development | ||
| mitochondrial fusion |
GO Hierarchy
- supramolecular fiber organization
- execution phase of apoptosis
- positive regulation of developmental pigmentation
- positive regulation of reproductive process
- regulation of cell cycle
biological process
metabolic process [inference]
cellular process [inference]
signal transduction [inference]
cellular localization [inference]
cellular component organization or biogenesis [inference]
cellular component organization [inference]
organelle organization [inference]
membrane organization [inference]
reproductive process [inference]
developmental process [inference]
homeostatic process [inference]
response to stimulus [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of signaling [inference]
regulation of localization [inference]
positive regulation of biological process [inference]
positive regulation of metabolic process [inference]
positive regulation of cellular process [inference]
positive regulation of response to stimulus [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
signal transduction [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of transmembrane transport [inference]
regulation of programmed cell death [inference]
positive regulation of cellular process [inference]
regulation of cellular component organization [inference]
regulation of biological quality [inference]
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| BH3 domain binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- apoptosis regulator BAX
- Functional Category
-
- E: Amino acid transport and metabolism
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| InterPro |
|---|
| Bcl-2 family |
| Bcl-2, Bcl-2 homology region 1-3 |
| Bcl-2-like superfamily |
| Bcl2-like |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:12704 | ataxia telangiectasia | |
| DOID:234 | colon adenocarcinoma | |
| DOID:9256 | colorectal cancer | |
| DOID:9952 | acute lymphoblastic leukemia |
