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nectin cell adhesion molecule 1

Summary

Gene Symbol

Nectin1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

58235

PubChem

58235

Alliance of Genome Resources

MGI:1926483

Annotation

Keyword

3D-structure
Cell adhesion
Cell membrane
Cell projection
Disulfide bond
Glycoprotein
Host-virus interaction
Immunoglobulin domain
Phosphoprotein
Receptor
Reference proteome
Repeat
Signal
Synapse
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9JKF6	Herpes virus entry mediator C Nectin cell adhesion molecule 1 Poliovirus receptor-related protein 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 22 in total

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GO Term	Evidence Code	PMID
lens morphogenesis in camera-type eye	IMP	15728677
desmosome organization	IMP	18703497
iron ion transport	IMP	18703497
homophilic cell adhesion via plasma membrane adhesion molecules	IDA	12826663
homophilic cell adhesion via plasma membrane adhesion molecules	IBA

GO Hierarchy

biological process

cellular process [inference]

cell adhesion [inference]

cell-cell adhesion

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to cell junction

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance

cell junction organization [inference]

cell-cell junction organization [inference]

desmosome organization

developmental process [inference]

anatomical structure morphogenesis [inference]

lens morphogenesis in camera-type eye

animal organ morphogenesis [inference]

sensory organ morphogenesis [inference]

eye morphogenesis [inference]

camera-type eye morphogenesis

embryonic morphogenesis [inference]

cochlea morphogenesis

anatomical structure development [inference]

tissue development [inference]

biomineral tissue development [inference]

tooth mineralization [inference]

enamel mineralization

retina development in camera-type eye

biological process involved in interspecies interaction between organisms [inference]

biological process involved in symbiotic interaction [inference]

biological process involved in interaction with host [inference]

movement in host [inference]

entry into host [inference]

viral entry into host cell

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to cell junction

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

transition metal ion transport [inference]

iron ion transport

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to cell junction

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

regulation of cellular component biogenesis [inference]

regulation of cell junction assembly [inference]

regulation of synapse assembly

regulation of cellular component organization [inference]

regulation of synapse organization

regulation of synapse assembly

regulation of cell junction assembly [inference]

regulation of synapse assembly

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GO Term	Evidence Code	PMID
plasma membrane	IDA	21798896
adherens junction	ISO
adherens junction	IDA	12515806 15328010 15728677
adherens junction	IBA
membrane	ISO	11090177

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

plasma membrane region [inference]

synaptic membrane [inference]

presynaptic active zone membrane

cell junction [inference]

synapse [inference]

neuron to neuron synapse [inference]

hippocampal mossy fiber to CA3 synapse

anchoring junction [inference]

cell-cell junction [inference]

growth cone membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

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GO Term	Evidence Code	PMID
virus receptor activity	IDA	38030279
protein binding	IPI	12826663 22512338
carbohydrate binding	ISO
carbohydrate binding	IEA
signaling receptor activity	IDA	11090177

GO Hierarchy

molecular function

binding [inference]

protein binding

identical protein binding

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

cell adhesion molecule binding

cell adhesion mediator activity

exogenous protein binding [inference]

virus receptor activity

molecular transducer activity [inference]

signaling receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

nectin-1

Functional Category

E: Amino acid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 3** entries
Gene Ontology
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
homophilic cell adhesion via plasma membrane adhesion molecules
protein localization to cell junction

Displaying **all 8** entries
InterPro
CD80-like, immunoglobulin C2-set
Immunoglobulin V-set domain
Immunoglobulin subtype
Immunoglobulin-like domain superfamily
Immunoglobulin-like domain
Immunoglobulin-like fold
Nectin-1, first immunoglobulin variable domain
Nectin-1, second immunoglobulin domain

Ortholog

Displaying entries **1 - 10** of 85 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	5818	Xenbase:XB-GENE-986141	HUMAN09862
Xenopus tropicalis	58235	Xenbase:XB-GENE-986141
Rattus norvegicus	192183	Xenbase:XB-GENE-986141	RATNO40446
Sus scrofa	397247		PIGXX35591
Canis lupus familiaris	489363		CANLF15190
Bos taurus	533492		BOVIN06616
Danio rerio	557665	Xenbase:XB-GENE-986141	DANRE13599
Macaca mulatta	710072		MACMU09544
Pan troglodytes	745188		PANTR04561
Monodelphis domestica	100031038		MONDO23840

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements