Raf-1 proto-oncogene, serine/threonine kinase
| UniProt | Protein Name |
|---|---|
| L7RRS6 |
|
| A0A0S2Z4L5 |
|
| P04049 |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| MAPK cascade | ||
| chromatin remodeling | ||
| protein phosphorylation | ||
| apoptotic process | ||
| signal transduction |
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein kinase activity | ||
| protein serine/threonine kinase activity | ||
| 3-phosphoinositide-dependent protein kinase activity | ||
| DNA-dependent protein kinase activity | ||
| AMP-activated protein kinase activity |
| Gene Ontology |
|---|
| ATP binding |
| Ras protein signal transduction |
| kinase activity |
| metal ion binding |
| nucleotide binding |
| phosphorylation |
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110432 | dilated cardiomyopathy 1NN | |
| DOID:0060583 | Noonan syndrome 5 | |
| DOID:0080549 | Noonan syndrome with multiple lentigines 2 | |
| DOID:2526 | prostate adenocarcinoma | |
| DOID:3490 | Noonan syndrome | |
| DOID:4074 | pancreatic adenocarcinoma |
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 5894 | Xenbase:XB-GENE-6053330 | ||
| 11836 | FB:FBgn0003079 | ||
| 24703 | RATNO29321 | ||
| 30716 | DANRE23895 | ||
| 109880 | FB:FBgn0003079 | ||
| 110157 | MOUSE50348 | ||
| 460182 | PANTR30470 | ||
| 484648 | CANLF07266 | ||
| 521196 | BOVIN18061 | ||
| 557109 | DANRE02712 |
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Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
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Last updated: December 8, 2025