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regenerating family member 1 alpha

Summary

Gene Symbol

REG1A

Organism

Homo sapiens (human)

External Links

NCBI Gene

5967

PubChem

5967

Alliance of Genome Resources

HGNC:9951

Annotation

Keyword

3D-structure
Direct protein sequencing
Disulfide bond
Glycoprotein
Lectin
Pyrrolidone carboxylic acid
Reference proteome
Secreted
Signal

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A8K7G6
P05451	Islet cells regeneration factor Islet of Langerhans regenerating protein Pancreatic stone protein Pancreatic thread protein Regenerating islet-derived protein 1-alpha Regenerating protein I alpha

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
signal transduction	IEA
positive regulation of cell population proliferation	IBA
response to peptide hormone	IBA
antimicrobial humoral immune response mediated by antimicrobial peptide	IBA

GO Hierarchy

biological process

immune system process [inference]

immune response [inference]

humoral immune response [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

cellular process [inference]

signal transduction

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

defense response to other organism [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

response to stimulus [inference]

response to stress [inference]

defense response [inference]

defense response to other organism [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

immune response [inference]

humoral immune response [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

defense response to other organism [inference]

antimicrobial humoral response [inference]

antimicrobial humoral immune response mediated by antimicrobial peptide

response to endogenous stimulus [inference]

response to hormone [inference]

response to peptide hormone

response to chemical [inference]

response to organic substance [inference]

response to hormone [inference]

response to peptide hormone

response to organonitrogen compound [inference]

response to peptide [inference]

response to peptide hormone

response to nitrogen compound [inference]

response to organonitrogen compound [inference]

response to peptide [inference]

response to peptide hormone

response to oxygen-containing compound [inference]

response to peptide [inference]

response to peptide hormone

biological regulation [inference]

regulation of biological process [inference]

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

regulation of cellular process [inference]

signal transduction

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

Displaying **all 2** entries
GO Term	Evidence Code	PMID
extracellular space	IBA
extracellular exosome	HDA	23533145

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular space

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
protein binding	IPI	28514442 33961781
growth factor activity	IDA	10526060
signaling receptor activity	IBA
peptidoglycan binding	IBA
oligosaccharide binding	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding [inference]

receptor ligand activity [inference]

growth factor activity

carbohydrate binding [inference]

oligosaccharide binding

carbohydrate derivative binding [inference]

glycosaminoglycan binding [inference]

peptidoglycan binding

molecular transducer activity [inference]

signaling receptor activity

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

growth factor activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

growth factor activity

molecular function inhibitor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

C-type lectin

Functional Category

M: Cell wall/membrane/envelope biogenesis
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 6** entries
Gene Ontology
antimicrobial humoral immune response mediated by antimicrobial peptide
disruption of cell wall in another organism
oligosaccharide binding
peptidoglycan binding
positive regulation of cell population proliferation
response to peptide hormone

Displaying **all 4** entries
InterPro
C-type lectin fold
C-type lectin, conserved site
C-type lectin-like/link domain superfamily
C-type lectin-like

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:9744	type 1 diabetes mellitus	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 41 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	5967	Xenbase:XB-GENE-952114
Xenopus tropicalis	5968	Xenbase:XB-GENE-952114
Caenorhabditis elegans	17533	WB:WBGene00020191
Caenorhabditis elegans	17534	WB:WBGene00020191
Mus musculus	19692	Xenbase:XB-GENE-952114	MOUSE48583
Mus musculus	19693		MOUSE48574
Rattus norvegicus	24714	Xenbase:XB-GENE-952114	RATNO29407
Xenopus tropicalis	67709	Xenbase:XB-GENE-952114
Xenopus tropicalis	83998	Xenbase:XB-GENE-952114
Danio rerio	130120	ZFIN:ZDB-GENE-070912-38

GlyTouCan

GlyComb

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UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements