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synaptopodin

Summary

Gene Symbol

Synpo

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

60324

PubChem

60324

Alliance of Genome Resources

RGD:620668

Annotation

Keyword

Actin-binding
Alternative splicing
Cell projection
Cytoskeleton
Glycoprotein
Methylation
Phosphoprotein
Reference proteome
Synapse
Tight junction

Proteins

Displaying **all 3** entries
UniProt	Protein Name
Q9Z327
A6IXC1
B1VKB4

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
regulation of long-term neuronal synaptic plasticity	ISO
postsynaptic modulation of chemical synaptic transmission	ISO
regulation of postsynaptic cytosolic calcium ion concentration	ISO
regulation of stress fiber assembly	ISO
modification of dendritic spine	IBA

GO Hierarchy

biological process

cellular process [inference]

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

organelle assembly [inference]

spine apparatus assembly

cellular component assembly [inference]

organelle assembly [inference]

spine apparatus assembly

cell junction organization [inference]

synapse organization [inference]

modification of synaptic structure [inference]

modification of postsynaptic structure [inference]

modification of dendritic spine

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

cognition [inference]

learning or memory [inference]

learning [inference]

associative learning [inference]

visual learning

behavior [inference]

learning or memory [inference]

learning [inference]

associative learning [inference]

visual learning

visual behavior [inference]

visual learning

homeostatic process [inference]

cellular homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration [inference]

regulation of postsynaptic cytosolic calcium ion concentration

chemical homeostasis [inference]

monoatomic ion homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration [inference]

regulation of postsynaptic cytosolic calcium ion concentration

monoatomic cation homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration [inference]

regulation of postsynaptic cytosolic calcium ion concentration

calcium ion homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration [inference]

regulation of postsynaptic cytosolic calcium ion concentration

intracellular chemical homeostasis [inference]

intracellular monoatomic ion homeostasis [inference]

intracellular monoatomic cation homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration [inference]

regulation of postsynaptic cytosolic calcium ion concentration

inorganic ion homeostasis [inference]

calcium ion homeostasis [inference]

intracellular calcium ion homeostasis [inference]

regulation of cytosolic calcium ion concentration [inference]

regulation of postsynaptic cytosolic calcium ion concentration

response to stimulus [inference]

response to abiotic stimulus [inference]

response to radiation [inference]

response to light stimulus [inference]

visual behavior [inference]

visual learning

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic plasticity [inference]

regulation of neuronal synaptic plasticity [inference]

regulation of long-term neuronal synaptic plasticity

postsynaptic modulation of chemical synaptic transmission

positive regulation of biological process [inference]

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of actin filament bundle assembly

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of cytoskeleton organization [inference]

positive regulation of actin filament bundle assembly

positive regulation of supramolecular fiber organization [inference]

positive regulation of actin filament bundle assembly

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic plasticity [inference]

regulation of neuronal synaptic plasticity [inference]

regulation of long-term neuronal synaptic plasticity

postsynaptic modulation of chemical synaptic transmission

regulation of actin filament-based process [inference]

regulation of actin cytoskeleton organization [inference]

regulation of actomyosin structure organization [inference]

regulation of stress fiber assembly

regulation of actin filament organization [inference]

regulation of actin filament bundle assembly [inference]

regulation of cellular component biogenesis [inference]

regulation of actin filament bundle assembly [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of actin filament bundle assembly

positive regulation of cellular process [inference]

positive regulation of cellular component biogenesis [inference]

positive regulation of actin filament bundle assembly

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of cytoskeleton organization [inference]

positive regulation of actin filament bundle assembly

positive regulation of supramolecular fiber organization [inference]

positive regulation of actin filament bundle assembly

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

positive regulation of organelle organization [inference]

positive regulation of cytoskeleton organization [inference]

positive regulation of actin filament bundle assembly

regulation of cytoskeleton organization [inference]

regulation of actin cytoskeleton organization [inference]

regulation of actomyosin structure organization [inference]

regulation of stress fiber assembly

regulation of actin filament organization [inference]

regulation of actin filament bundle assembly [inference]

positive regulation of cytoskeleton organization [inference]

positive regulation of actin filament bundle assembly

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of cytoskeleton organization [inference]

positive regulation of actin filament bundle assembly

positive regulation of supramolecular fiber organization [inference]

positive regulation of actin filament bundle assembly

regulation of supramolecular fiber organization [inference]

regulation of actin filament organization [inference]

regulation of actin filament bundle assembly [inference]

positive regulation of supramolecular fiber organization [inference]

positive regulation of actin filament bundle assembly

regulation of biological quality [inference]

regulation of synaptic plasticity [inference]

regulation of neuronal synaptic plasticity [inference]

regulation of long-term neuronal synaptic plasticity

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
Schaffer collateral - CA1 synapse	ISO
postsynaptic density	IEA
perikaryon	IEA
plasma membrane	IEA ISO
actin cytoskeleton	IBA ISO ISS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cytosol

membrane [inference]

plasma membrane

Z disc

cell junction [inference]

synapse [inference]

anchoring junction [inference]

cell-cell junction [inference]

tight junction [inference]

bicellular tight junction

actin filament bundle [inference]

contractile actin filament bundle [inference]

stress fiber

actomyosin [inference]

stress fiber

perikaryon

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

spine apparatus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

actin cytoskeleton

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

cytoskeleton [inference]

actin cytoskeleton

postsynaptic specialization [inference]

postsynaptic density

cell periphery

Displaying 1 entry
GO Term	Evidence Code	PMID
actin binding	IBA ISO ISS

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

cytoskeletal protein binding [inference]

actin binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

Neurotransmitter-gated ion-channel ligand-binding domain

Functional Category

C: Energy production and conversion
K: Transcription
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
actin binding
modification of dendritic spine
positive regulation of actin filament bundle assembly
spine apparatus assembly

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:784	chronic kidney disease	Alliance of Genome Resources

Ortholog

Displaying entries **61 - 70** of 77 in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Microtus oregoni	121440663	111838_0:00560d
Microtus oregoni	121445237	111838_0:0061c6
Dipodomys spectabilis	122118240	105255_0:002b30
Panthera leo	122226237		PANLE12956
Marmota monax	124103468	9995_0:002507
Sciurus carolinensis	124986666	30640_0:0022dc
Perognathus longimembris pacificus	125340015	214514_0:004471
Perognathus longimembris pacificus	125345125	214514_0:005109
Myodes glareolus	125390241	447135_0:003fe0
Microtus fortis	126511006	100897_0:002d86