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endothelin converting enzyme-like 1

Summary

Gene Symbol

Ecel1

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

60417

PubChem

60417

Alliance of Genome Resources

RGD:61806

Annotation

Keyword

Disulfide bond
Glycoprotein
Metal-binding
Metalloprotease
Reference proteome
Signal-anchor
Transmembrane helix
Zinc

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A6JWK8
D4AD32
Q9JHL3	Damage-induced neuronal endopeptidase Xce protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 5** entries
GO Term	Evidence Code	PMID
proteolysis	IEA
neuropeptide signaling pathway	IDA	12417666
intracellular signal transduction	IDA	12417666
respiratory system process	IEA ISO ISS
protein processing	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein processing

protein maturation [inference]

protein processing

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein processing

protein maturation [inference]

protein processing

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein processing

protein maturation [inference]

protein processing

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein processing

protein maturation [inference]

protein processing

cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

neuropeptide signaling pathway

intracellular signal transduction

multicellular organismal process [inference]

system process [inference]

respiratory system process

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

G protein-coupled receptor signaling pathway [inference]

neuropeptide signaling pathway

intracellular signal transduction

Displaying **all 2** entries
GO Term	Evidence Code	PMID
membrane	IEA
plasma membrane	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
metal ion binding	IEA
metalloendopeptidase activity	IBA IEA ISO TAS	12417666

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

endopeptidase activity [inference]

metalloendopeptidase activity

metallopeptidase activity [inference]

metalloendopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

endopeptidase activity [inference]

metalloendopeptidase activity

metallopeptidase activity [inference]

metalloendopeptidase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

endothelin-converting enzyme-like 1

Functional Category

G: Carbohydrate transport and metabolism
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 5** entries
Gene Ontology
hydrolase activity
metal ion binding
metalloendopeptidase activity
metallopeptidase activity
proteolysis

Displaying **all 5** entries
InterPro
Metallopeptidase, catalytic domain superfamily
Peptidase M13, C-terminal domain
Peptidase M13, N-terminal domain
Peptidase M13, domain 2
Peptidase M13

Disease

Disease Ontology

Displaying **all 2** entries
DO ID	Disease Name	Source
DOID:0050646	distal arthrogryposis	Alliance of Genome Resources
DOID:0111594	distal arthrogryposis type 5D	Alliance of Genome Resources

Ortholog

Displaying entries **51 - 60** of **151** in total

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Felis catus	101084132		FELCA20855
Gorilla gorilla gorilla	101133364		GORGO27214
Oryzias latipes	101160572		ORYLA03531
Octodon degus	101592572	10160_0:002c0e	OCTDE15895
Jaculus jaculus	101607167	51337_0:0018ae
Mustela putorius furo	101682466		MUSPF04410
Heterocephalus glaber	101705383	10181_0:004035

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Summary

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Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements