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retinal outer segment membrane protein 1

Summary

Gene Symbol

ROM1

Organism

Homo sapiens (human)

External Links

NCBI Gene

6094

PubChem

6094

Alliance of Genome Resources

HGNC:10254

Annotation

Keyword

3D-structure
Cell adhesion
Cell projection
Disease variant
Disulfide bond
Proteomics identification
Reference proteome
Retinitis pigmentosa
Transmembrane helix
Vision

Proteins

Displaying 1 entry
UniProt	Protein Name
Q03395	Tetraspanin-23

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

1

2

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Last »
GO Term	Evidence Code	PMID
cell adhesion	IEA
visual perception	TAS	1610568
regulation of gene expression	IEA
photoreceptor cell outer segment organization	IEA
detection of light stimulus involved in visual perception	IEA

GO Hierarchy

biological process

cellular process [inference]

cell adhesion

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation [inference]

photoreceptor cell differentiation [inference]

eye photoreceptor cell differentiation [inference]

camera-type eye photoreceptor cell differentiation

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to cilium [inference]

protein localization to non-motile cilium [inference]

protein localization to photoreceptor outer segment

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

photoreceptor cell outer segment organization

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein complex oligomerization [inference]

multicellular organismal process [inference]

system process [inference]

nervous system process [inference]

sensory perception [inference]

sensory perception of light stimulus [inference]

visual perception

developmental process [inference]

anatomical structure development [inference]

system development [inference]

vasculature development [inference]

retina vasculature development in camera-type eye

cellular developmental process [inference]

cell differentiation [inference]

neuron differentiation [inference]

photoreceptor cell differentiation [inference]

eye photoreceptor cell differentiation [inference]

camera-type eye photoreceptor cell differentiation

response to stimulus [inference]

response to external stimulus [inference]

detection of external stimulus [inference]

detection of light stimulus [inference]

detection of visible light [inference]

detection of light stimulus involved in visual perception

detection of light stimulus involved in sensory perception [inference]

detection of light stimulus involved in visual perception

response to abiotic stimulus [inference]

response to radiation [inference]

response to light stimulus [inference]

detection of light stimulus [inference]

detection of visible light [inference]

detection of light stimulus involved in visual perception

detection of light stimulus involved in sensory perception [inference]

detection of light stimulus involved in visual perception

detection of abiotic stimulus [inference]

detection of light stimulus [inference]

detection of visible light [inference]

detection of light stimulus involved in visual perception

detection of light stimulus involved in sensory perception [inference]

detection of light stimulus involved in visual perception

detection of stimulus [inference]

detection of external stimulus [inference]

detection of light stimulus [inference]

detection of visible light [inference]

detection of light stimulus involved in visual perception

detection of light stimulus involved in sensory perception [inference]

detection of light stimulus involved in visual perception

detection of abiotic stimulus [inference]

detection of light stimulus [inference]

detection of visible light [inference]

detection of light stimulus involved in visual perception

detection of light stimulus involved in sensory perception [inference]

detection of light stimulus involved in visual perception

detection of stimulus involved in sensory perception [inference]

detection of light stimulus involved in sensory perception [inference]

detection of light stimulus involved in visual perception

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to cilium [inference]

protein localization to non-motile cilium [inference]

protein localization to photoreceptor outer segment

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to cilium [inference]

protein localization to non-motile cilium [inference]

protein localization to photoreceptor outer segment

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of cellular metabolic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression

Displaying **all 2** entries
GO Term	Evidence Code	PMID
plasma membrane	IBA
photoreceptor outer segment membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

ciliary membrane [inference]

photoreceptor outer segment membrane

plasma membrane region [inference]

cell projection membrane [inference]

ciliary membrane [inference]

photoreceptor outer segment membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein binding	IPI	32296183
protein homodimerization activity	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

protein homodimerization activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

photoreceptor outer segment membrane glycoprotein 2

Functional Category

J: Translation, ribosomal structure and biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
visual perception

Displaying **all 5** entries
InterPro
Peripherin, extracellular domain
Peripherin/rom-1, conserved site
Peripherin/rom-1
Tetraspanin, EC2 domain superfamily
Tetraspanin/Peripherin

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:0110383	retinitis pigmentosa 7	Alliance of Genome Resources

International Collaboration

GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

GlyCosmos Portal v4.4.0

Last updated: December 8, 2025

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OrthoDB (Group)

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Acknowledgements