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Guidelines

MIRAGE

gamma-glutamyltransferase 7

Summary

Gene Symbol

GGT7

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 615929
PubChem: 615929

Annotation

Keyword

Acyltransferase
Glutathione biosynthesis
Glycoprotein
Hydrolase
Phosphoprotein
Reference proteome
Signal-anchor
Transmembrane helix
Zymogen

Proteins

Displaying 1 entry
UniProt	Protein Name
Q0V8L2	Gamma-glutamyltransferase 7 Gamma-glutamyltransferase-like 3 Gamma-glutamyltranspeptidase 7

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
glutathione biosynthetic process
glutathione catabolic process	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

nonribosomal peptide biosynthetic process [inference]

glutathione biosynthetic process

amide metabolic process [inference]

peptide metabolic process [inference]

peptide biosynthetic process [inference]

nonribosomal peptide biosynthetic process [inference]

glutathione biosynthetic process

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

nonribosomal peptide biosynthetic process [inference]

glutathione biosynthetic process

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

peptide biosynthetic process [inference]

nonribosomal peptide biosynthetic process [inference]

glutathione biosynthetic process

organonitrogen compound biosynthetic process [inference]

peptide biosynthetic process [inference]

nonribosomal peptide biosynthetic process [inference]

glutathione biosynthetic process

catabolic process [inference]

organic substance catabolic process [inference]

glutathione catabolic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

nonribosomal peptide biosynthetic process [inference]

glutathione biosynthetic process

organic substance biosynthetic process [inference]

organonitrogen compound biosynthetic process [inference]

peptide biosynthetic process [inference]

nonribosomal peptide biosynthetic process [inference]

glutathione biosynthetic process

cellular metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

nonribosomal peptide biosynthetic process [inference]

glutathione biosynthetic process

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

nonribosomal peptide biosynthetic process [inference]

glutathione biosynthetic process

organic substance metabolic process [inference]

glutathione metabolic process [inference]

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

peptide biosynthetic process [inference]

nonribosomal peptide biosynthetic process [inference]

glutathione biosynthetic process

organonitrogen compound biosynthetic process [inference]

peptide biosynthetic process [inference]

nonribosomal peptide biosynthetic process [inference]

glutathione biosynthetic process

organic substance catabolic process [inference]

glutathione catabolic process

organic substance biosynthetic process [inference]

organonitrogen compound biosynthetic process [inference]

peptide biosynthetic process [inference]

nonribosomal peptide biosynthetic process [inference]

glutathione biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

nonribosomal peptide biosynthetic process [inference]

glutathione biosynthetic process

cellular biosynthetic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

nonribosomal peptide biosynthetic process [inference]

glutathione biosynthetic process

Displaying 1 entry
GO Term	Evidence Code	PMID
plasma membrane	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

Displaying **all 2** entries
GO Term	Evidence Code	PMID
glutathione hydrolase activity	IEA	30032202
leukotriene C4 gamma-glutamyl transferase activity

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

aminoacyltransferase activity [inference]

leukotriene C4 gamma-glutamyl transferase activity

hydrolase activity [inference]

peptidase activity [inference]

omega peptidase activity [inference]

glutathione hydrolase activity

threonine-type peptidase activity [inference]

glutathione hydrolase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

omega peptidase activity [inference]

glutathione hydrolase activity

threonine-type peptidase activity [inference]

glutathione hydrolase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

gamma-glutamyltransferase 7

Functional Category

E: Amino acid transport and metabolism
I: Lipid transport and metabolism
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 5** entries
Gene Ontology
glutathione catabolic process
glutathione hydrolase activity
glutathione metabolic process
hydrolase activity
transferase activity

Displaying **all 4** entries
InterPro
Gamma-glutamyltranspeptidase, large subunit, C-terminal domain
Gamma-glutamyltranspeptidase, small subunit
Gamma-glutamyltranspeptidase
Nucleophile aminohydrolases, N-terminal

Rhea

H₂O + glutathione

L-glutamate + L-cysteinylglycine

Enzyme

3.4.19.13

PMID

H₂O + an S-substituted glutathione

an S-substituted L-cysteinylglycine + L-glutamate

Enzyme

3.4.19.13

PMID

an α-amino acid

5-L-glutamyl amino acid

Enzyme

2.3.2.2

PMID

Ortholog

Displaying entries **1 - 10** of 94 in total

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Last »
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	2686		HUMAN56619
Rattus norvegicus	156275		RATNO25724
Mus musculus	207182		MOUSE32232
Pan troglodytes	458194		PANTR24703
Canis lupus familiaris	485847		CANLF09478
Macaca mulatta	706813		MACMU02353
Monodelphis domestica	100028557		MONDO06797
Equus caballus	100054524		HORSE21582
Taeniopygia guttata	100224250		TAEGU12042
Oryctolagus cuniculus	100346442		RABIT10054

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025