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ribosomal protein lateral stalk subunit P0

Summary

Gene Symbol

RPLP0

Organism

Homo sapiens (human)

External Links

NCBI Gene

6175

PubChem

6175

Alliance of Genome Resources

HGNC:10371

Annotation

Keyword

3D-structure
Alternative splicing
Cytoplasm
Direct protein sequencing
Isopeptide bond
Nucleus
Phosphoprotein
Reference proteome
Ribosomal protein
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
P05388	60S acidic ribosomal protein P0 60S ribosomal protein L10E

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
translation	NAS	12962325
ribosomal large subunit assembly
cytoplasmic translation	IBA IC NAS	23636399 25901680

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

cytoplasmic translation

amide metabolic process [inference]

peptide metabolic process [inference]

peptide biosynthetic process [inference]

cytoplasmic translation

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

cytoplasmic translation

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

peptide biosynthetic process [inference]

cytoplasmic translation

protein metabolic process [inference]

cytoplasmic translation

organonitrogen compound biosynthetic process [inference]

peptide biosynthetic process [inference]

cytoplasmic translation

biosynthetic process [inference]

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

cytoplasmic translation

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

cytoplasmic translation

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

cytoplasmic translation

organonitrogen compound biosynthetic process [inference]

peptide biosynthetic process [inference]

cytoplasmic translation

cellular metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

cytoplasmic translation

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

cytoplasmic translation

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

cytoplasmic translation

primary metabolic process [inference]

protein metabolic process [inference]

cytoplasmic translation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule biosynthetic process [inference]

cytoplasmic translation

protein metabolic process [inference]

cytoplasmic translation

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

peptide biosynthetic process [inference]

cytoplasmic translation

protein metabolic process [inference]

cytoplasmic translation

organonitrogen compound biosynthetic process [inference]

peptide biosynthetic process [inference]

cytoplasmic translation

organic substance biosynthetic process [inference]

macromolecule biosynthetic process [inference]

cytoplasmic translation

organonitrogen compound biosynthetic process [inference]

peptide biosynthetic process [inference]

cytoplasmic translation

cellular process [inference]

cellular metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

cytoplasmic translation

cellular biosynthetic process [inference]

macromolecule biosynthetic process [inference]

cytoplasmic translation

cellular nitrogen compound biosynthetic process [inference]

amide biosynthetic process [inference]

peptide biosynthetic process [inference]

cytoplasmic translation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein-RNA complex assembly [inference]

ribosomal large subunit assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein-RNA complex assembly [inference]

ribosomal large subunit assembly

protein-RNA complex organization [inference]

protein-RNA complex assembly [inference]

ribosomal large subunit assembly

Displaying entries **1 - 5** of 13 in total

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GO Term	Evidence Code	PMID
membrane	HDA	19946888
focal adhesion	HDA	21423176
postsynaptic density	EXP IDA	21170055
postsynapse	EXP IDA	23071613
ribonucleoprotein complex	IDA	17289661

GO Hierarchy

cellular component

protein-containing complex [inference]

ribonucleoprotein complex

ribosomal subunit [inference]

large ribosomal subunit [inference]

cytosolic large ribosomal subunit

cellular anatomical entity [inference]

cell junction [inference]

anchoring junction [inference]

cell-substrate junction [inference]

focal adhesion

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

ribosome [inference]

cytosolic ribosome

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

ribosome [inference]

cytosolic ribosome

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

postsynaptic specialization [inference]

postsynaptic density

postsynapse

supramolecular complex [inference]

ribonucleoprotein granule [inference]

cytoplasmic ribonucleoprotein granule

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein binding	IPI	15121898 15303970 15380484 19188445 22720776 24658146 25416956 28514442 33961781
large ribosomal subunit rRNA binding	IBA
structural constituent of ribosome	IBA IDA NAS	12962325 23636399 3323886
RNA binding	HDA	22658674 22681889

GO Hierarchy

molecular function

structural molecule activity [inference]

structural constituent of ribosome

binding [inference]

protein binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

rRNA binding [inference]

large ribosomal subunit rRNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

60S acidic ribosomal protein

Functional Category

E: Amino acid transport and metabolism
J: Translation, ribosomal structure and biogenesis
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
cytoplasmic translation
large ribosomal subunit rRNA binding

Displaying **all 5** entries
InterPro
Large ribosomal subunit protein uL10, eukaryotes
Large ribosomal subunit protein uL10-like domain superfamily
Large ribosomal subunit protein uL10-like, insertion domain superfamily
Large ribosomal subunit protein uL10-like, insertion domain
Large ribosomal subunit protein uL10

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:14250	Down syndrome	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 99 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	11837		MGI:1927636	MOUSE45526
Drosophila melanogaster	40451		FB:FBgn0000100
Danio rerio	58101		ZFIN:ZDB-GENE-000629-1	DANRE35988
Rattus norvegicus	64205		RGD:621247	RATNO05494
Caenorhabditis elegans	172943		WB:WBGene00004408
Bos taurus	286868			BOVIN09632
Xenopus laevis	379826		Xenbase:XB-GENE-976216
Xenopus tropicalis	394664		Xenbase:XB-GENE-976211
Pan troglodytes	452301	9598_0:00348b		PANTR49169
Macaca mulatta	574363			MACMU02965

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.1.0

Last updated: December 9, 2024