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interferon, beta 3

Summary

Gene Symbol

IFNB3

Organism

Bos taurus (domestic cattle)

External Links

NCBI Gene: 618946
PubChem: 618946

Annotation

Keyword

Antiviral defense
Cytokine
Disulfide bond
Glycoprotein
Reference proteome
Secreted
Signal

Proteins

Displaying 1 entry
UniProt	Protein Name
P01577

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
adaptive immune response
T cell activation involved in immune response
natural killer cell activation involved in immune response
defense response	IEA	22301074 30032202
humoral immune response

GO Hierarchy

biological process

immune system process [inference]

immune effector process [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

immune response [inference]

leukocyte activation [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

lymphocyte activation [inference]

lymphocyte activation involved in immune response [inference]

lymphocyte differentiation [inference]

B cell differentiation

natural killer cell activation [inference]

natural killer cell activation involved in immune response

T cell activation [inference]

T cell activation involved in immune response

B cell activation [inference]

lymphocyte proliferation [inference]

B cell proliferation

cellular process [inference]

cell activation [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

leukocyte activation [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

lymphocyte activation [inference]

lymphocyte activation involved in immune response [inference]

lymphocyte differentiation [inference]

B cell differentiation

natural killer cell activation [inference]

natural killer cell activation involved in immune response

T cell activation [inference]

T cell activation involved in immune response

B cell activation [inference]

lymphocyte proliferation [inference]

B cell proliferation

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway

cell population proliferation [inference]

leukocyte proliferation [inference]

mononuclear cell proliferation [inference]

lymphocyte proliferation [inference]

B cell proliferation

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

mononuclear cell differentiation [inference]

lymphocyte differentiation [inference]

B cell differentiation

multicellular organismal process [inference]

cell activation [inference]

cell activation involved in immune response [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

leukocyte activation [inference]

leukocyte activation involved in immune response [inference]

lymphocyte activation involved in immune response [inference]

lymphocyte activation [inference]

lymphocyte activation involved in immune response [inference]

lymphocyte differentiation [inference]

B cell differentiation

natural killer cell activation [inference]

natural killer cell activation involved in immune response

T cell activation [inference]

T cell activation involved in immune response

B cell activation [inference]

lymphocyte proliferation [inference]

B cell proliferation

developmental process [inference]

cellular developmental process [inference]

cell differentiation [inference]

leukocyte differentiation [inference]

mononuclear cell differentiation [inference]

lymphocyte differentiation [inference]

B cell differentiation

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus

defense response to other organism [inference]

defense response to symbiont [inference]

defense response to virus

response to stimulus [inference]

response to stress [inference]

defense response

defense response to other organism [inference]

defense response to symbiont [inference]

defense response to virus

immune response [inference]

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus

defense response to other organism [inference]

defense response to symbiont [inference]

defense response to virus

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to virus [inference]

defense response to virus

defense response to other organism [inference]

defense response to symbiont [inference]

defense response to virus

response to chemical [inference]

response to organic substance [inference]

response to organic cyclic compound [inference]

response to dsRNA [inference]

response to exogenous dsRNA

response to nitrogen compound [inference]

response to dsRNA [inference]

response to exogenous dsRNA

biological regulation [inference]

regulation of biological process [inference]

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway [inference]

cytokine-mediated signaling pathway

Displaying **all 2** entries
GO Term	Evidence Code	PMID
extracellular region	IEA	22301074 30032202
extracellular space

GO Hierarchy

cellular component

cellular anatomical entity [inference]

Displaying **all 3** entries
GO Term	Evidence Code	PMID
cytokine activity
cytokine receptor binding	IEA	22301074 30032202
type I interferon receptor binding

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

cytokine receptor binding

type I interferon receptor binding

receptor ligand activity [inference]

cytokine activity

protein-containing complex binding [inference]

type I interferon receptor binding

molecular function regulator activity [inference]

signaling receptor regulator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

cytokine activity

molecular function activator activity [inference]

signaling receptor activator activity [inference]

receptor ligand activity [inference]

cytokine activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

interferon beta

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
cytokine activity
cytokine receptor binding
defense response to virus

Displaying **all 2** entries
InterPro
Four-helical cytokine-like, core
Interferon alpha/beta/delta

Ortholog

Displaying entries **1 - 10** of 50 in total

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Species	Gene ID	Orthologous MAtrix
Homo sapiens	3456	HUMAN96570
Mus musculus	15977	MOUSE41031
Rattus norvegicus	24481	RATNO32557
Sus scrofa	445459	PIGXX15391
Pan troglodytes	473183	PANTR43721
Felis catus	493849	FELCA30504
Macaca mulatta	711414	MACMU12788
Monodelphis domestica	100021258	MONDO28278
Equus caballus	100052545	HORSE22071
Equus caballus	100052658	HORSE22071