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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
glutathione peroxidase 4
Summary
- Gene Symbol
-
- Gpx4
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- Alternative initiation
- Alternative splicing
- Cytoplasm
- Developmental protein
- Lipid metabolism
- Mitochondrion
- Nucleus
- Peroxidase
- Phosphoprotein
- Reference proteome
- Selenium
- Selenocysteine
- Transit peptide
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein polymerization | ||
| multicellular organism growth | ||
| arachidonic acid metabolic process | ||
| chromatin organization | ||
| apoptotic process |
GO Hierarchy
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| selenium binding | ||
| phospholipid-hydroperoxide glutathione peroxidase activity | ||
| identical protein binding | ||
| glutathione peroxidase activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Rodentia
- Group Name
- phospholipid hydroperoxide glutathione peroxidase
- Functional Category
-
- J: Translation, ribosomal structure and biogenesis
- T: Signal transduction mechanisms
- V: Defense mechanisms
| InterPro |
|---|
| Glutathione peroxidase |
| Thioredoxin-like superfamily |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050861 | colorectal adenocarcinoma | |
| DOID:0112298 | spondylometaphyseal dysplasia Sedaghatian type | |
| DOID:10591 | pre-eclampsia | |
| DOID:1184 | nephrotic syndrome | |
| DOID:219 | colon cancer | |
| DOID:3021 | acute kidney failure | |
| DOID:3717 | gastric adenocarcinoma | |
| DOID:9256 | colorectal cancer |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 2879 | HGNC:4556 | HUMAN39330 | ||
| 29328 | 10116_1:002ab1 | RGD:69226 | RATNO39426 | |
| 37194 | FB:FBgn0034415 | |||
| 38413 | FB:FBgn0035438 | |||
| 184981 | WB:WBGene00009165 | |||
| 187630 | WB:WBGene00011045 | |||
| 188313 | WB:WBGene00020373 | |||
| 286809 | BOVIN33375 | |||
| 352928 | ZFIN:ZDB-GENE-030410-2 | |||
| 352929 | ZFIN:ZDB-GENE-030410-3 |
