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secretin receptor

Summary

Gene Symbol

SCTR

Organism

Homo sapiens (human)

External Links

NCBI Gene

6344

PubChem

6344

Alliance of Genome Resources

HGNC:10608

Annotation

Keyword

3D-structure
Cell membrane
G-protein coupled receptor
Glycoprotein
Phosphoprotein
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q8IV17
P47872

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
diet induced thermogenesis	ISS
cell surface receptor signaling pathway	IEA
G protein-coupled receptor signaling pathway	IDA	7612008
adenylate cyclase-modulating G protein-coupled receptor signaling pathway	IBA
adenylate cyclase-activating G protein-coupled receptor signaling pathway	ISS

GO Hierarchy

biological process

metabolic process [inference]

adaptive thermogenesis [inference]

diet induced thermogenesis

cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway

adenylate cyclase-activating G protein-coupled receptor signaling pathway

cellular component organization or biogenesis [inference]

cellular component organization [inference]

regulation of cellular component size [inference]

regulation of cell size [inference]

cell volume homeostasis [inference]

intracellular water homeostasis

homeostatic process [inference]

cellular homeostasis [inference]

cell volume homeostasis [inference]

intracellular water homeostasis

intracellular chemical homeostasis [inference]

intracellular water homeostasis

chemical homeostasis [inference]

intracellular chemical homeostasis [inference]

intracellular water homeostasis

response to stimulus [inference]

response to external stimulus [inference]

response to extracellular stimulus [inference]

response to nutrient levels

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic plasticity

regulation of cellular process [inference]

signal transduction [inference]

cell surface receptor signaling pathway

G protein-coupled receptor signaling pathway

adenylate cyclase-modulating G protein-coupled receptor signaling pathway

adenylate cyclase-activating G protein-coupled receptor signaling pathway

regulation of cell communication [inference]

regulation of trans-synaptic signaling [inference]

modulation of chemical synaptic transmission [inference]

regulation of synaptic plasticity

regulation of biological quality [inference]

regulation of anatomical structure size [inference]

regulation of cellular component size [inference]

regulation of cell size [inference]

cell volume homeostasis [inference]

intracellular water homeostasis

Displaying **all 5** entries
GO Term	Evidence Code	PMID
cytoplasmic microtubule	IDA	23264731
plasma membrane	ISS
plasma membrane	TAS
plasma membrane	IBA
basolateral plasma membrane	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

basolateral plasma membrane

supramolecular complex [inference]

supramolecular polymer [inference]

supramolecular fiber [inference]

polymeric cytoskeletal fiber [inference]

microtubule [inference]

cytoplasmic microtubule

Displaying **all 5** entries
GO Term	Evidence Code	PMID
G protein-coupled peptide receptor activity	IBA
secretin receptor activity	IDA	32811827 33008599 7612008
secretin receptor activity	IBA
peptide hormone binding	IBA
peptide hormone binding	IPI	7612008

GO Hierarchy

molecular function

binding [inference]

amide binding [inference]

peptide binding [inference]

peptide hormone binding

hormone binding [inference]

peptide hormone binding

molecular transducer activity [inference]

signaling receptor activity [inference]

peptide receptor activity [inference]

G protein-coupled peptide receptor activity

transmembrane signaling receptor activity [inference]

G protein-coupled receptor activity [inference]

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

vasoactive intestinal polypeptide

Functional Category

E: Amino acid transport and metabolism
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 4** entries
Gene Ontology
G protein-coupled peptide receptor activity
adenylate cyclase-modulating G protein-coupled receptor signaling pathway
cell surface receptor signaling pathway
peptide hormone binding

Displaying **all 5** entries
InterPro
GPCR family 2, extracellular hormone receptor domain superfamily
GPCR, family 2, extracellular hormone receptor domain
GPCR, family 2, secretin-like, conserved site
GPCR, family 2, secretin-like
GPCR, family 2-like, 7TM

Ortholog

Displaying entries **31 - 40** of 50 in total

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Species	Gene ID	Orthologous MAtrix
Nannospalax galili	103745461	NANGA25646
Serinus canaria	103814293	SERCA06585
Rhinopithecus roxellana	104661497	RHIRO25192
Pteropus vampyrus	105296157	PTEVA08842
Macaca nemestrina	105492638	MACNE05019
Mandrillus leucophaeus	105542075	MANLE03538
Cercocebus atys	105588124	CERAT28884
Aotus nancymaae	105728144	AOTNA08987
Propithecus coquereli	105810637	PROCO16343
Microcebus murinus	105862666	MICMU09252

GlyTouCan

GlyComb

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UniCarb-DR

LM-GlycoRepo

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OrthoDB (Group)

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Acknowledgements