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MIRAGE
C-C motif chemokine ligand 2
Summary
- Gene Symbol
-
- CCL2
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Chemotaxis
- Cytokine
- Direct protein sequencing
- Disulfide bond
- Glycoprotein
- Inflammatory response
- Pyrrolidone carboxylic acid
- Reference proteome
- Secreted
- Signal
- Proteins
| UniProt | Protein Name |
|---|---|
| P13500 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| angiogenesis | ||
| monocyte chemotaxis | ||
| protein phosphorylation | ||
| chemotaxis | ||
| inflammatory response |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of localization [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
regulation of cellular metabolic process [inference]
regulation of transmembrane transport [inference]
regulation of cell population proliferation [inference]
regulation of programmed cell death [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cell cycle [inference]
regulation of cell motility [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| extracellular region | ||
| extracellular region | ||
| extracellular space |
| GO Term | Evidence Code | PMID |
|---|---|---|
| CCR2 chemokine receptor binding | ||
| chemoattractant activity | ||
| CCR chemokine receptor binding |
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- C-C motif chemokine 3
- Functional Category
-
- J: Translation, ribosomal structure and biogenesis
- O: Posttranslational modification, protein turnover, chaperones
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| cell chemotaxis |
| chemokine activity |
| cytokine activity |
| eosinophil chemotaxis |
| immune response |
| InterPro |
|---|
| Chemokine beta/gamma/delta |
| Chemokine interleukin-8-like domain |
| Chemokine interleukin-8-like superfamily |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:2377 | multiple sclerosis | |
| DOID:2841 | asthma | |
| DOID:2957 | pulmonary tuberculosis | |
| DOID:326 | ischemia | |
| DOID:3312 | bipolar disorder | |
| DOID:4989 | pancreatitis | |
| DOID:5844 | myocardial infarction | |
| DOID:684 | hepatocellular carcinoma | |
| DOID:783 | end stage renal disease | |
| DOID:8923 | skin melanoma |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 100089603 | ORNAN09034 | ||
| 100172740 | PONAB12270 | ||
| 100919171 | SARHA00006 | ||
| 100952119 | OTOGA05835 | ||
| 100981087 | PANPA16990 | ||
| 101134802 | GORGO34183 | ||
| 102135739 | MACFA13494 | ||
| 103242710 | CHLSB05437 | ||
| 103264824 | CARSF26867 | ||
| 104675111 | RHIRO25326 |
