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syndecan 2

Summary

Gene Symbol

SDC2

Aliases

CD362
SYND2
fibroglycan
syndecan proteoglycan 2

Organism

Homo sapiens (human)

External Links

NCBI Gene

6383

HGNC

10659

KEGG Gene ID

hsa:6383

PubChem

6383

Alliance of Genome Resources

HGNC:10659

Annotation

Keyword

3D-structure
Differentiation
Heparan sulfate
Neurogenesis
Phosphoprotein
Proteomics identification
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
E9PBI9
P34741	Fibroglycan Heparan sulfate proteoglycan core protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
cell migration	IBA
biological_process	ND
regulation of dendrite morphogenesis	ISS
dendrite morphogenesis	IBA

GO Hierarchy

biological process

cellular process [inference]

cell motility [inference]

cell migration

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

dendrite morphogenesis

developmental process [inference]

anatomical structure morphogenesis [inference]

cellular anatomical entity morphogenesis [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

neuron projection morphogenesis [inference]

dendrite morphogenesis

biological regulation [inference]

regulation of biological process [inference]

regulation of developmental process [inference]

regulation of anatomical structure morphogenesis [inference]

regulation of dendrite morphogenesis

regulation of dendrite development [inference]

regulation of dendrite morphogenesis

regulation of cellular process [inference]

regulation of cellular component organization [inference]

regulation of cell projection organization [inference]

regulation of plasma membrane bounded cell projection organization [inference]

regulation of neuron projection development [inference]

regulation of dendrite development [inference]

regulation of dendrite morphogenesis

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GO Term	Evidence Code	PMID
endoplasmic reticulum lumen
Golgi lumen
cell surface	IBA
plasma membrane	IDA TAS
collagen-containing extracellular matrix	HDA	27068509

GO Hierarchy

cellular component

cellular anatomical entity [inference]

cell surface

membrane [inference]

plasma membrane

external encapsulating structure [inference]

extracellular matrix [inference]

collagen-containing extracellular matrix

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

vacuolar lumen [inference]

lysosomal lumen

Displaying **all 3** entries
GO Term	Evidence Code	PMID
PDZ domain binding	IPI	18256285
protein binding	IPI	11356864 18093920 22660413 32296183 32814053 9660868
identical protein binding	IPI	18093920 21988832

GO Hierarchy

molecular function

binding [inference]

protein binding

protein domain specific binding [inference]

PDZ domain binding

identical protein binding

Gene Ontology information from NCBI Gene and UniProt.

Human Protein Atlas

ENSG00000169439

Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.

Data available from v23.0.proteinatlas.org. Image credit: Human Protein Atlas

KEGG BRITE Database

Orthology

K16336

Name

syndecan 2

References

Disease

Disease Ontology

Displaying entries **51 - 60** of **217** in total

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DO ID	Disease Name	Source
DOID:0110282	autosomal recessive limb-girdle muscular dystrophy type 2H	DisGeNET DisGeNET
DOID:0110283	autosomal recessive limb-girdle muscular dystrophy type 2J	DisGeNET DisGeNET
DOID:0110284	autosomal recessive limb-girdle muscular dystrophy type 2L	DisGeNET DisGeNET
DOID:0110285	autosomal recessive limb-girdle muscular dystrophy type 2Q	DisGeNET DisGeNET
DOID:0110286	obsolete autosomal recessive limb-girdle muscular dystrophy type 2R	DisGeNET DisGeNET
DOID:0110287	autosomal recessive limb-girdle muscular dystrophy type 2S	DisGeNET DisGeNET
DOID:0110289	autosomal recessive limb-girdle muscular dystrophy type 2Y	DisGeNET DisGeNET
DOID:0110292	autosomal recessive limb-girdle muscular dystrophy type 2O	DisGeNET DisGeNET
DOID:0110293	autosomal recessive limb-girdle muscular dystrophy type 2P	DisGeNET DisGeNET
DOID:0110294	autosomal recessive limb-girdle muscular dystrophy type 2T	DisGeNET DisGeNET

Ortholog

Displaying entries **61 - 64** of 64 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Nannospalax galili	103745844		NANGA09111
Corvus moneduloides	116453929		CORMO09234
Carlito syrichta	103265735		CARSF25797
Strigops habroptila	115612684		STRHB14414

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: August 19, 2024