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MIRAGE
transient receptor potential cation channel, subfamily V, member 4
Summary
- Gene Symbol
-
- Trpv4
- Organism
- Mus musculus (house mouse)
Annotation
- Keyword
-
- 3D-structure
- ANK repeat
- ATP-binding
- Calcium channel
- Calmodulin-binding
- Cell junction
- Cell membrane
- Cilium
- Glycoprotein
- Lipid-binding
- Metal-binding
- Phosphoprotein
- Reference proteome
- Repeat
- Transmembrane helix
- Proteins
| UniProt | Protein Name |
|---|---|
| Q9EPK8 |
|
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| negative regulation of transcription by RNA polymerase II | ||
| response to hypoxia | ||
| diet induced thermogenesis | ||
| calcium ion transport | ||
| intracellular calcium ion homeostasis |
GO Hierarchy
biological process
cellular process [inference]
homeostatic process [inference]
response to stimulus [inference]
localization [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of immune system process [inference]
regulation of metabolic process [inference]
regulation of biosynthetic process [inference]
positive regulation of biosynthetic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
negative regulation of metabolic process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
regulation of nitrogen compound metabolic process [inference]
regulation of macromolecule metabolic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
regulation of signaling [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
positive regulation of metabolic process [inference]
positive regulation of biosynthetic process [inference]
positive regulation of macromolecule metabolic process [inference]
positive regulation of cellular metabolic process [inference]
positive regulation of cellular process [inference]
negative regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
regulation of cell communication [inference]
regulation of cellular metabolic process [inference]
regulation of nucleobase-containing compound metabolic process [inference]
positive regulation of cellular metabolic process [inference]
regulation of cellular biosynthetic process [inference]
regulation of macromolecule biosynthetic process [inference]
regulation of gene expression [inference]
positive regulation of macromolecule biosynthetic process [inference]
positive regulation of cellular biosynthetic process [inference]
positive regulation of cellular process [inference]
negative regulation of cellular process [inference]
regulation of cellular component organization [inference]
regulation of cell motility [inference]
regulation of multicellular organismal process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| cytoplasmic microtubule | ||
| cytoplasmic microtubule | ||
| plasma membrane | ||
| plasma membrane | ||
| plasma membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| actin binding | ||
| osmosensor activity | ||
| osmosensor activity | ||
| protein kinase C binding | ||
| protein kinase C binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- transient receptor potential cation channel subfamily v member
- Functional Category
-
- I: Lipid transport and metabolism
- J: Translation, ribosomal structure and biogenesis
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| calcium channel activity |
| monoatomic ion channel activity |
| monoatomic ion transport |
| InterPro |
|---|
| Ankyrin repeat-containing domain superfamily |
| Ankyrin repeat |
| Ion transport domain |
| Transient receptor potential cation channel subfamily V |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0110555 | autosomal dominant nonsyndromic deafness 25 |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 7442 | SGD:S000005613 | ||
| 22368 | SGD:S000005613 | ||
| 29465 | SGD:S000005613 | ||
| 51393 | SGD:S000005613 | ||
| 55503 | SGD:S000005613 | ||
| 56302 | SGD:S000005613 | ||
| 59341 | HUMAN15325 | ||
| 63873 | Xenbase:XB-GENE-998899 | ||
| 64177 | SGD:S000005613 | ||
| 66026 | RATNO05919 |
