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alpha 1,4-galactosyltransferase

Summary

Gene Symbol

A4galt

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

63888

KEGG Gene ID

rno:63888

PubChem

63888

Alliance of Genome Resources

RGD:621583

Annotation

Keyword

Glycoprotein
Glycosyltransferase
Golgi apparatus
Lipid biosynthesis
Reference proteome
Signal-anchor
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
A6HT88	Alpha-1,4-N-acetylglucosaminyltransferase Alpha-1,4-galactosyltransferase Globotriaosylceramide synthase UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase
Q9JI93	Alpha-1,4-N-acetylglucosaminyltransferase Alpha-1,4-galactosyltransferase Alpha4Gal-T1 Globotriaosylceramide synthase UDP-galactose:beta-D-galactosyl-beta1-R 4-alpha-D-galactosyltransferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
globoside biosynthetic process	ISO
protein O-linked glycosylation
glycosphingolipid biosynthetic process	IBA
plasma membrane organization	ISO

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

biosynthetic process [inference]

cellular biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

cellular metabolic process [inference]

cellular biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process

globoside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

sphingolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

primary metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process

globoside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

sphingolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process

globoside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation

organic substance metabolic process [inference]

lipid metabolic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process

globoside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

sphingolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process

globoside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein O-linked glycosylation

carbohydrate derivative metabolic process [inference]

carbohydrate derivative biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

liposaccharide metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process

globoside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

organonitrogen compound metabolic process [inference]

sphingolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein O-linked glycosylation

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

organic substance biosynthetic process [inference]

lipid biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

carbohydrate derivative biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

organonitrogen compound biosynthetic process [inference]

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

cellular process [inference]

cellular metabolic process [inference]

cellular biosynthetic process [inference]

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

cellular lipid metabolic process [inference]

membrane lipid metabolic process [inference]

glycolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process

globoside biosynthetic process

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

sphingolipid metabolic process [inference]

glycosphingolipid metabolic process [inference]

globoside metabolic process [inference]

globoside biosynthetic process

glycosphingolipid biosynthetic process

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

membrane lipid biosynthetic process [inference]

glycolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

sphingolipid biosynthetic process [inference]

glycosphingolipid biosynthetic process

globoside biosynthetic process

cellular component organization or biogenesis [inference]

cellular component organization [inference]

membrane organization [inference]

plasma membrane organization

Displaying **all 2** entries
GO Term	Evidence Code	PMID
Golgi membrane	IEA
membrane	ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

Displaying entries **1 - 5** of 7 in total

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GO Term	Evidence Code	PMID
acetylglucosaminyltransferase activity
galactosyltransferase activity	ISS
galactosyltransferase activity	ISO
galactosyltransferase activity	IDA	10854428
galactosyltransferase activity	IBA

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity [inference]

UDP-glycosyltransferase activity [inference]

acetylglucosaminyltransferase activity

UDP-galactosyltransferase activity [inference]

lactosylceramide 4-alpha-galactosyltransferase activity

hexosyltransferase activity [inference]

acetylglucosaminyltransferase activity

galactosyltransferase activity

UDP-galactosyltransferase activity [inference]

lactosylceramide 4-alpha-galactosyltransferase activity

binding [inference]

toxic substance binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

alpha--galactosyltransferase

Functional Category

J: Translation, ribosomal structure and biogenesis
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 2** entries
InterPro
Glycosyltransferase, DXD sugar-binding motif
Nucleotide-diphospho-sugar transferases

KEGG BRITE Database

Orthology

K01988

Name

lactosylceramide 4-alpha-galactosyltransferase [EC:2.4.1.228]

References

10748143

Reactions

Displaying **all 3** entries
KEGG Reaction	Enzyme	Acceptor	Product
R05960	2.4.1.228	G84224TW	G00059MO
R11376	2.4.1.228	G00061MO	G33020YH
R11375	2.4.1.228	G58896AZ	G12460DL

Rhea

RHEA:11924

a β-D-Gal-(1→4)-β-D-Glc-(1↔1)-Cer(d18:1(4E)) + UDP-α-D-galactose

H⁺ + a globoside Gb3Cer (d18:1(4E)) + UDP

Enzyme

2.4.1.228

PMID

LIPID MAPS Gene / Proteome Database

LMPD ID: LMP012683
Gene Name: alpha 1,4-galactosyltransferase

Ortholog

Displaying entries **21 - 30** of 69 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	100495236	Xenbase:XB-GENE-493407
Sus scrofa	100524987		PIGXX24962
Meleagris gallopavo	100550373		MELGA00770
Anolis carolinensis	100558212		ANOCA07401
Loxodonta africana	100654825		LOXAF04423
Cavia porcellus	100721247		CAVPO13227
Cricetulus griseus	100770462		CRIGR17465
Sarcophilus harrisii	100925030		SARHA05010
Otolemur garnettii	100951617		OTOGA17335
Pan paniscus	100981788		PANPA24012

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

LIPID MAPS Gene / Proteome Database

International Collaboration

Acknowledgements