succinate dehydrogenase complex subunit D
| UniProt | Protein Name |
|---|---|
| O14521 |
|
| A0A0S2Z4H7 |
|
| A0A0S2Z4J3 |
|
| GO Term | Evidence Code | PMID |
|---|---|---|
| tricarboxylic acid cycle | ||
| tricarboxylic acid cycle | ||
| tricarboxylic acid cycle | ||
| tricarboxylic acid cycle | ||
| mitochondrial electron transport, succinate to ubiquinone |
| GO Term | Evidence Code | PMID |
|---|---|---|
| mitochondrion | ||
| mitochondrial envelope | ||
| mitochondrial inner membrane | ||
| mitochondrial inner membrane | ||
| mitochondrial inner membrane |
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| succinate dehydrogenase (ubiquinone) activity | ||
| electron transfer activity | ||
| heme binding | ||
| heme binding |
| InterPro |
|---|
| Fumarate reductase/succinate dehydrogenase, transmembrane subunit |
| Succinate dehydrogenase [ubiquinone] cytochrome b small subunit, CybS |
Tissue with high expression from Human Protein Atlas. Tissues that are highly expressed are highlighted.
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050773 | paraganglioma | |
| DOID:0060537 | mitochondrial complex II deficiency | |
| DOID:0080533 | Carney-Stratakis syndrome |
| HPO ID | HPO Term |
|---|---|
| HP:0000544 | External ophthalmoplegia |
| HP:0000545 | Myopia |
| HP:0000580 | Pigmentary retinopathy |
| HP:0000618 | Blindness |
| HP:0000639 | Nystagmus |
| HP:0000717 | Autism |
| HP:0000726 | Dementia |
| HP:0000737 | Irritability |
| HP:0000740 | Episodic paroxysmal anxiety |
| HP:0000767 | Pectus excavatum |
| Disease ID | Disease Name |
|---|---|
| ORPHA:201 |
|
| OMIM:606864 |
|
| ORPHA:276621 |
|
| OMIM:168000 |
|
| OMIM:619167 |
|
| ORPHA:3208 |
|
| ORPHA:29072 |
|
| ORPHA:100093 |
|
| ORPHA:97286 |
|
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 6392 | Xenbase:XB-GENE-5855162 | ||
| 66925 | MOUSE60714 | ||
| 281481 | BOVIN06454 | ||
| 363061 | RATNO40893 | ||
| 436762 | DANRE36120 | ||
| 445500 | DANRE09183 | ||
| 451547 | PANTR04323 | ||
| 711326 | MACMU11001 | ||
| 100032261 | MONDO21545 | ||
| 100048954 | PIGXX35399 |
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Supported by JST NBDC Grant Number JPMJND2204
Partly supported by NIH Common Fund Grant #1U01GM125267-01
This work is licensed under Creative Commons Attribution 4.0 International
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Last updated: December 8, 2025