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SEC13 homolog, nuclear pore and COPII coat complex component

Summary

Gene Symbol

SEC13

Organism

Homo sapiens (human)

External Links

NCBI Gene

6396

PubChem

6396

Alliance of Genome Resources

HGNC:10697

JoGo

SEC13

TogoVar

SEC13

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Cytoplasmic vesicle
Direct protein sequencing
ER-Golgi transport
Endoplasmic reticulum
Lysosome
Membrane
Nuclear pore complex
Phosphoprotein
Proteomics identification
Reference proteome
Repeat
WD repeat

Proteins

Displaying **all 2** entries
UniProt	Protein Name
P55735	GATOR2 complex protein SEC13 SEC13-like protein 1 SEC13-related protein
A8MWR8

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 12 in total

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GO Term	Evidence Code	PMID
protein import into nucleus	IBA
intracellular protein transport	NAS	7987303
nucleocytoplasmic transport	NAS	27016207
cellular response to nutrient levels	IDA	35831510 36528027
positive regulation of TOR signaling	IBA

GO Hierarchy

biological process

cellular process [inference]

cell communication [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport

nuclear transport [inference]

nucleocytoplasmic transport

import into nucleus [inference]

protein import into nucleus

COPII-coated vesicle cargo loading

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

establishment of protein localization to organelle [inference]

protein import into nucleus

cellular response to stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

vesicle organization [inference]

vesicle budding from membrane [inference]

COPII-coated vesicle budding

membrane organization [inference]

vesicle budding from membrane [inference]

COPII-coated vesicle budding

response to stimulus [inference]

response to external stimulus [inference]

response to extracellular stimulus [inference]

response to nutrient levels [inference]

cellular response to nutrient levels

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels

cellular response to external stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels

cellular response to stimulus [inference]

cellular response to extracellular stimulus [inference]

cellular response to nutrient levels

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of localization [inference]

transport [inference]

vesicle cargo loading [inference]

COPII-coated vesicle cargo loading

intracellular transport [inference]

intracellular protein transport

nuclear transport [inference]

nucleocytoplasmic transport

import into nucleus [inference]

protein import into nucleus

COPII-coated vesicle cargo loading

organic substance transport [inference]

protein transport [inference]

intracellular protein transport

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

mRNA transport

nitrogen compound transport [inference]

protein transport [inference]

intracellular protein transport

nucleobase-containing compound transport [inference]

nucleic acid transport [inference]

RNA transport [inference]

mRNA transport

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of RNA localization [inference]

RNA transport [inference]

mRNA transport

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport

nuclear transport [inference]

nucleocytoplasmic transport

import into nucleus [inference]

protein import into nucleus

COPII-coated vesicle cargo loading

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport

nuclear transport [inference]

nucleocytoplasmic transport

import into nucleus [inference]

protein import into nucleus

COPII-coated vesicle cargo loading

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to nucleus [inference]

protein import into nucleus

establishment of protein localization to organelle [inference]

protein import into nucleus

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

establishment of protein localization to organelle [inference]

protein import into nucleus

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling

positive regulation of TORC1 signaling

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of TOR signaling [inference]

negative regulation of TORC1 signaling

regulation of intracellular signal transduction [inference]

regulation of TOR signaling [inference]

negative regulation of TOR signaling [inference]

negative regulation of TORC1 signaling

positive regulation of TOR signaling

positive regulation of TORC1 signaling

regulation of TORC1 signaling [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of TOR signaling [inference]

negative regulation of TORC1 signaling

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling

positive regulation of TORC1 signaling

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling

positive regulation of TORC1 signaling

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of TOR signaling [inference]

negative regulation of TORC1 signaling

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling

positive regulation of TORC1 signaling

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling

positive regulation of TORC1 signaling

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling

positive regulation of TORC1 signaling

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of TOR signaling [inference]

negative regulation of TORC1 signaling

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of TOR signaling [inference]

negative regulation of TORC1 signaling

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of TOR signaling [inference]

negative regulation of TORC1 signaling

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling

positive regulation of TORC1 signaling

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of TOR signaling [inference]

negative regulation of TORC1 signaling

regulation of intracellular signal transduction [inference]

regulation of TOR signaling [inference]

negative regulation of TOR signaling [inference]

negative regulation of TORC1 signaling

positive regulation of TOR signaling

positive regulation of TORC1 signaling

regulation of TORC1 signaling [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of TOR signaling [inference]

negative regulation of TORC1 signaling

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling

positive regulation of TORC1 signaling

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling

positive regulation of TORC1 signaling

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of TOR signaling [inference]

negative regulation of TORC1 signaling

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling

positive regulation of TORC1 signaling

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of TOR signaling [inference]

negative regulation of TORC1 signaling

regulation of intracellular signal transduction [inference]

regulation of TOR signaling [inference]

negative regulation of TOR signaling [inference]

negative regulation of TORC1 signaling

positive regulation of TOR signaling

positive regulation of TORC1 signaling

regulation of TORC1 signaling [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of TOR signaling [inference]

negative regulation of TORC1 signaling

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling

positive regulation of TORC1 signaling

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling

positive regulation of TORC1 signaling

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of TOR signaling [inference]

negative regulation of TORC1 signaling

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of intracellular signal transduction [inference]

positive regulation of TOR signaling

positive regulation of TORC1 signaling

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of intracellular signal transduction [inference]

negative regulation of TOR signaling [inference]

negative regulation of TORC1 signaling

Displaying entries **11 - 15** of 18 in total

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GO Term	Evidence Code	PMID
COPII vesicle coat	IBA
nuclear pore outer ring	NAS	15146057
nuclear pore outer ring	IDA	17360435
nuclear pore outer ring	IBA
intracellular membrane-bounded organelle	IDA

GO Hierarchy

cellular component

protein-containing complex [inference]

GATOR2 complex

membrane protein complex [inference]

membrane coat [inference]

vesicle coat [inference]

COPII vesicle coat

nuclear protein-containing complex [inference]

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

endoplasmic reticulum membrane

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

transport vesicle membrane [inference]

ER to Golgi transport vesicle membrane

coated vesicle membrane [inference]

ER to Golgi transport vesicle membrane

bounding membrane of organelle [inference]

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane

transport vesicle membrane [inference]

ER to Golgi transport vesicle membrane

coated vesicle membrane [inference]

ER to Golgi transport vesicle membrane

envelope [inference]

organelle envelope [inference]

nuclear envelope

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

kinetochore

intracellular organelle [inference]

intracellular membrane-bounded organelle

intracellular non-membrane-bounded organelle [inference]

kinetochore

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

supramolecular complex [inference]

kinetochore

Displaying **all 3** entries
GO Term	Evidence Code	PMID
structural molecule activity	IBA
protein binding	IPI	15146057 16189514 16407955 16957052 17428803 18160040 18692470 19638414 19822759 20696395 24981860 25201882 25416956 26496610 27194810 28514442 32296183 32814053 33961781 35271311
identical protein binding	IPI	18160040 27194810