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glutamyl aminopeptidase

Summary

Gene Symbol

Enpep

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

64017

PubChem

64017

Alliance of Genome Resources

RGD:621228

Annotation

Keyword

Alternative splicing
Aminopeptidase
Calcium
Cell membrane
Direct protein sequencing
Disulfide bond
Glycoprotein
Metal-binding
Metalloprotease
Reference proteome
Signal-anchor
Transmembrane helix
Zinc

Proteins

Displaying 1 entry
UniProt	Protein Name
P50123	Aminopeptidase A

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
angiogenesis	ISO
angiogenesis	IEA
angiotensin maturation	ISO
angiotensin maturation	IEA
regulation of systemic arterial blood pressure by renin-angiotensin	ISS

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

amide metabolic process [inference]

peptide metabolic process [inference]

peptide hormone processing [inference]

angiotensin maturation

peptide catabolic process

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

peptide hormone processing [inference]

angiotensin maturation

peptide catabolic process

protein metabolic process [inference]

proteolysis

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

angiotensin maturation

protein maturation [inference]

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

angiotensin maturation

organonitrogen compound catabolic process [inference]

peptide catabolic process

catabolic process [inference]

cellular catabolic process [inference]

peptide catabolic process

organic substance catabolic process [inference]

organonitrogen compound catabolic process [inference]

peptide catabolic process

hormone metabolic process [inference]

peptide hormone processing [inference]

angiotensin maturation

cellular metabolic process [inference]

cellular catabolic process [inference]

peptide catabolic process

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

angiotensin maturation

protein maturation [inference]

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

angiotensin maturation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

angiotensin maturation

protein maturation [inference]

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

angiotensin maturation

organonitrogen compound metabolic process [inference]

peptide metabolic process [inference]

peptide hormone processing [inference]

angiotensin maturation

peptide catabolic process

protein metabolic process [inference]

proteolysis

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

angiotensin maturation

protein maturation [inference]

protein processing

signaling receptor ligand precursor processing [inference]

peptide hormone processing [inference]

angiotensin maturation

organonitrogen compound catabolic process [inference]

peptide catabolic process

organic substance catabolic process [inference]

organonitrogen compound catabolic process [inference]

peptide catabolic process

cellular process [inference]

cell population proliferation

cellular metabolic process [inference]

cellular catabolic process [inference]

peptide catabolic process

cell motility [inference]

cell migration

multicellular organismal process [inference]

system process [inference]

endocrine process [inference]

regulation of systemic arterial blood pressure by hormone [inference]

regulation of systemic arterial blood pressure by renin-angiotensin

developmental process [inference]

anatomical structure formation involved in morphogenesis [inference]

angiogenesis

anatomical structure development [inference]

glomerulus development

biological regulation [inference]

regulation of biological quality [inference]

regulation of blood pressure

regulation of systemic arterial blood pressure [inference]

regulation of systemic arterial blood pressure mediated by a chemical signal [inference]

regulation of systemic arterial blood pressure by hormone [inference]

regulation of systemic arterial blood pressure by renin-angiotensin

regulation of hormone levels [inference]

hormone metabolic process [inference]

peptide hormone processing [inference]

angiotensin maturation

Displaying entries **1 - 5** of 16 in total

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GO Term	Evidence Code	PMID
extracellular space	IBA
cytoplasm	IBA
plasma membrane	ISS
plasma membrane	ISO
plasma membrane	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

apical plasma membrane

cell projection membrane [inference]

brush border membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle

apical part of cell

side of membrane [inference]

external side of plasma membrane

cluster of actin-based cell projections [inference]

brush border

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GO Term	Evidence Code	PMID
aminopeptidase activity	ISO
aminopeptidase activity	IDA	10978538 16537183
aminopeptidase activity	IEA
obsolete glutamyl aminopeptidase activity	IEA
peptidase activity	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity

metallopeptidase activity

metalloexopeptidase activity [inference]

metalloaminopeptidase activity

exopeptidase activity [inference]

aminopeptidase activity

metalloaminopeptidase activity

metalloexopeptidase activity [inference]

metalloaminopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity

metallopeptidase activity

metalloexopeptidase activity [inference]

metalloaminopeptidase activity

exopeptidase activity [inference]

aminopeptidase activity

metalloaminopeptidase activity

metalloexopeptidase activity [inference]

metalloaminopeptidase activity

binding [inference]

amide binding [inference]

peptide binding

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

zinc ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

Aminopeptidase N-like , N-terminal domain

Functional Category

C: Energy production and conversion
E: Amino acid transport and metabolism
H: Coenzyme transport and metabolism

Displaying **all 10** entries
Gene Ontology
aminopeptidase activity
hydrolase activity
metal ion binding
metalloaminopeptidase activity
metallopeptidase activity
peptide binding
peptide catabolic process
proteolysis
regulation of blood pressure
zinc ion binding

Alliance of Genome Resources

Expression

Displaying 1 entry
Location	References
brush border membrane	PMID:12110004

Ortholog

Displaying entries **71 - 80** of 96 in total

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Species	Gene ID	Orthologous MAtrix
Salmo salar	106610934	SALSA140394
Equus asinus asinus	106829790	EQUAS17585
Sinocyclocheilus grahami	107585235	SINGR35023
Ictalurus punctatus	108263853	ICTPU27111
Rhinopithecus bieti	108541020	RHIBE22942
Cyprinus carpio carpio	109100448	CYPCA65527
Cyprinus carpio carpio	109101324	CYPCA78602
Crocodylus porosus	109309384	CROPO16912
Vulpes vulpes	112930983	VULVU26374
Pseudonaja textilis	113434780	PSETE05366

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Acknowledgements