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selectin P ligand

Summary

Gene Symbol

SELPLG

Organism

Homo sapiens (human)

External Links

NCBI Gene

6404

PubChem

6404

Alliance of Genome Resources

HGNC:10722

Annotation

Keyword

3D-structure
Alternative splicing
Cell adhesion
Cleavage on pair of basic residues
Direct protein sequencing
Disulfide bond
Host cell receptor for virus entry
Host-virus interaction
Phosphoprotein
Pyrrolidone carboxylic acid
Reference proteome
Repeat
Sialic acid
Signal
Sulfation
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q14242	Selectin P ligand

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
leukocyte tethering or rolling	IBA IDA	25425738
leukocyte adhesive activation	ISS
leukocyte migration	IDA	25425738
viral entry into host cell	IEA
cell adhesion	TAS	7505206

GO Hierarchy

biological process

immune system process [inference]

leukocyte activation [inference]

leukocyte adhesive activation

leukocyte migration

cellular process [inference]

cell activation [inference]

leukocyte activation [inference]

leukocyte adhesive activation

cell adhesion

cell-cell adhesion [inference]

leukocyte cell-cell adhesion [inference]

leukocyte adhesion to vascular endothelial cell [inference]

leukocyte tethering or rolling

cell motility [inference]

cell migration [inference]

leukocyte migration

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to interleukin-6

multicellular organismal process [inference]

cell activation [inference]

leukocyte activation [inference]

leukocyte adhesive activation

biological process involved in interspecies interaction between organisms [inference]

biological process involved in symbiotic interaction [inference]

biological process involved in interaction with host [inference]

movement in host [inference]

entry into host [inference]

viral entry into host cell

response to stimulus [inference]

response to chemical [inference]

response to organic substance [inference]

response to cytokine [inference]

response to interleukin-6 [inference]

cellular response to interleukin-6

cellular response to cytokine stimulus [inference]

cellular response to interleukin-6

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to interleukin-6

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to interleukin-6

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to organic substance [inference]

cellular response to cytokine stimulus [inference]

cellular response to interleukin-6

Displaying **all 4** entries
GO Term	Evidence Code	PMID
membrane	TAS	7505206 7541799
plasma membrane raft	IDA	25425738
plasma membrane	IBA IDA TAS	21696602
uropod	IDA	21696602

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

plasma membrane region [inference]

plasma membrane raft

membrane microdomain [inference]

membrane raft [inference]

plasma membrane raft

cell projection [inference]

plasma membrane bounded cell projection [inference]

uropod

Displaying **all 3** entries
GO Term	Evidence Code	PMID
protein binding	IPI	11081633 18196517 19118202 26627825 28011641
signaling receptor binding	NAS	7505206
virus receptor activity	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding

signaling receptor binding

exogenous protein binding [inference]

virus receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

P-selectin glycoprotein ligand 1

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
L: Replication, recombination and repair

Displaying 1 entry
Gene Ontology
leukocyte tethering or rolling

Displaying 1 entry
InterPro
P-selectin glycoprotein ligand 1

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:3407	carotid artery disease	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 30 in total

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Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	20345		MGI:106689	MOUSE45013
Rattus norvegicus	363930		RGD:1307971	RATNO05927
Pan troglodytes	452211	9598_0:0034d2		PANTR06814
Canis lupus familiaris	611673			CANLF10416
Bos taurus	617434			BOVIN09709
Macaca mulatta	706046			MACMU02984
Callithrix jacchus	100411671			CALJA46161
Pongo abelii	100442089	9601_0:0034a2
Nomascus leucogenys	100587302			NOMLE02402
Cavia porcellus	100712957			CAVPO03352

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Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements