GlyCosmos Portal

Submissions

xylosyltransferase 2

Summary

Gene Symbol

XYLT2

Aliases

PXYLT2
XT-II
protein xylosyltransferase 2

Organism

Homo sapiens (human)

External Links

NCBI Gene

64132

GGDB ID

gg170

HGNC

15517

mRNA

NM_022167

map

17q21.3-17q22

Protein

NP_071450

OMIM

608125

KEGG Gene ID

hsa:64132

PubChem

64132

Alliance of Genome Resources

HGNC:15517

JoGo

XYLT2

TogoVar

XYLT2

Annotation

Keyword

Alternative splicing
Disease variant
Disulfide bond
Glycoprotein
Glycosyltransferase
Golgi apparatus
Magnesium
Manganese
Metal-binding
Proteomics identification
Reference proteome
Secreted
Signal-anchor
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q9H1B5	Peptide O-xylosyltransferase 1 Xylosyltransferase II
B4DT06	Xylosyltransferase II

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 8 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
glycosaminoglycan biosynthetic process	NAS
heparan sulfate proteoglycan biosynthetic process	IMP
heparan sulfate proteoglycan biosynthetic process	IBA
heparan sulfate proteoglycan biosynthetic process	IEA
proteoglycan biosynthetic process	IEA

GO Hierarchy

biological process

cellular process [inference]

metabolic process [inference]

biosynthetic process [inference]

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via xylose [inference]

proteoglycan biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via xylose [inference]

proteoglycan biosynthetic process

macromolecule metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan biosynthetic process

macromolecule biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via xylose [inference]

proteoglycan biosynthetic process

protein metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

proteoglycan biosynthetic process

heparan sulfate proteoglycan metabolic process [inference]

heparan sulfate proteoglycan biosynthetic process

chondroitin sulfate proteoglycan metabolic process [inference]

chondroitin sulfate proteoglycan biosynthetic process

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via xylose [inference]

proteoglycan biosynthetic process

primary metabolic process [inference]

protein metabolic process [inference]

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

proteoglycan biosynthetic process

heparan sulfate proteoglycan metabolic process [inference]

heparan sulfate proteoglycan biosynthetic process

chondroitin sulfate proteoglycan metabolic process [inference]

chondroitin sulfate proteoglycan biosynthetic process

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via xylose [inference]

proteoglycan biosynthetic process

carbohydrate derivative metabolic process [inference]

aminoglycan metabolic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

glycosaminoglycan metabolic process [inference]

glycosaminoglycan biosynthetic process

glycoprotein metabolic process [inference]

proteoglycan metabolic process [inference]

proteoglycan biosynthetic process

heparan sulfate proteoglycan metabolic process [inference]

heparan sulfate proteoglycan biosynthetic process

chondroitin sulfate proteoglycan metabolic process [inference]

chondroitin sulfate proteoglycan biosynthetic process

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via xylose [inference]

proteoglycan biosynthetic process

carbohydrate derivative biosynthetic process [inference]

aminoglycan biosynthetic process [inference]

glycosaminoglycan biosynthetic process

glycoprotein biosynthetic process [inference]

protein O-linked glycosylation [inference]

protein O-linked glycosylation via xylose [inference]

proteoglycan biosynthetic process

Displaying entries **1 - 5** of 7 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
Golgi membrane	TAS
Golgi membrane	IEA
extracellular region	IDA
extracellular region	IEA
obsolete extracellular space

GO Hierarchy

cellular component

cellular anatomical structure [inference]

extracellular region

membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

Displaying entries **1 - 5** of 11 in total

1

2

3

Next ›

Last »
GO Term	Evidence Code	PMID
magnesium ion binding	IDA
UDP-glycosyltransferase activity	IEA
glycosyltransferase activity	IEA
manganese ion binding	IDA
protein xylosyltransferase activity	EXP

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity

UDP-glycosyltransferase activity

UDP-xylosyltransferase activity [inference]

protein xylosyltransferase activity

pentosyltransferase activity [inference]

xylosyltransferase activity [inference]

UDP-xylosyltransferase activity [inference]

protein xylosyltransferase activity

catalytic activity, acting on a protein [inference]

protein xylosyltransferase activity

binding [inference]

small molecule binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

magnesium ion binding

transition metal ion binding [inference]

manganese ion binding

Gene Ontology information from NCBI Gene and UniProt.

GlycoGene Database (GGDB)

GGDB ID

gg170

Gene Symbol

XYLT2

Orthologous Gene

Displaying **all 3** entries
Species	Protein	mRNA
Caenorhabditis elegans	AAO85277	AY241928
Rattus norvegicus	NP_071632	NM_022296
Mus musculus	CAC185567	AJ291751

KEGG BRITE Database

Orthology

K00771

Name

protein xylosyltransferase [EC:2.4.2.26]

References

11099377

Rhea

RHEA:50192

UDP-α-D-xylose

H⁺ + UDP

Enzyme

2.4.2.26

PMID

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:2738	pseudoxanthoma elasticum	Alliance of Genome Resources

The Human Phenotype Ontology

Displaying entries **1 - 10** of 76 in total

1

2

3

4

5

…

Next ›

Last »
HPO ID	HPO Term
HP:0000007	Autosomal recessive inheritance
HP:0000164	Abnormality of the dentition
HP:0000233	Thin vermilion border
HP:0000297	Facial hypotonia
HP:0000316	Hypertelorism
HP:0000343	Long philtrum
HP:0000358	Posteriorly rotated ears
HP:0000369	Low-set ears
HP:0000391	Thickened helices
HP:0000407	Sensorineural hearing impairment

Displaying **all 3** entries
Disease ID	Disease Name
OMIM:264800	autosomal recessive inherited pseudoxanthoma elasticum
OMIM:605822	spondylo-ocular syndrome
ORPHA:85194	spondylo-ocular syndrome

PubChem Disease

MedGen Diseases

OMIM Phenotypes

KEGG Diseases

Gene-Disease-Co-Occurrences-in-Literature (PubChem)

Ortholog

Displaying **all 7** entries
Species	Gene ID	Alliance of Genome Resources
Danio rerio	563446	ZFIN:ZDB-GENE-081022-125
Xenopus laevis	108701100	Xenbase:XB-GENE-6486005
Xenopus tropicalis	448400	Xenbase:XB-GENE-993408
Mus musculus	217119	MGI:2444797
Rattus norvegicus	64134	RGD:619765
Caenorhabditis elegans	190099	WB:WBGene00005024
Drosophila melanogaster	38288	FB:FBgn0015360

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

GlycoGene Database (GGDB)

KEGG BRITE Database

PubChem Disease

International Collaboration

Acknowledgements