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MIRAGE
purinergic receptor P2Y12
Summary
- Gene Symbol
-
- P2RY12
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Blood coagulation
- Cell membrane
- Disease variant
- Disulfide bond
- G-protein coupled receptor
- Glycoprotein
- Phosphoprotein
- Receptor
- Reference proteome
- Transducer
- Transmembrane helix
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| G protein-coupled adenosine receptor signaling pathway | ||
| monoatomic ion transport | ||
| ion transport | ||
| substrate-dependent cell migration, cell extension | ||
| G protein-coupled receptor signaling pathway |
GO Hierarchy
biological process
cellular process [inference]
response to stimulus [inference]
biological regulation [inference]
regulation of biological process [inference]
regulation of locomotion [inference]
positive regulation of biological process [inference]
regulation of response to stimulus [inference]
regulation of cellular process [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| plasma membrane | ||
| plasma membrane | ||
| cell surface | ||
| membrane | ||
| cell projection membrane |
| GO Term | Evidence Code | PMID |
|---|---|---|
| G protein-coupled adenosine receptor activity | ||
| G protein-coupled ADP receptor activity | ||
| G protein-coupled ADP receptor activity | ||
| guanyl-nucleotide exchange factor activity | ||
| G protein-coupled purinergic nucleotide receptor activity |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- g-protein coupled receptor 87
- Functional Category
-
- E: Amino acid transport and metabolism
- K: Transcription
- T: Signal transduction mechanisms
| Gene Ontology |
|---|
| G protein-coupled purinergic nucleotide receptor activity |
| G protein-coupled purinergic nucleotide receptor signaling pathway |
| InterPro |
|---|
| G protein-coupled receptor, rhodopsin-like |
| GPCR, rhodopsin-like, 7TM |
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0050830 | peripheral artery disease | |
| DOID:0060692 | platelet-type bleeding disorder 8 | |
| DOID:2841 | asthma | |
| DOID:6713 | cerebrovascular disease | |
| DOID:9352 | type 2 diabetes mellitus |
Ortholog
| Species | Gene ID | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|
| 64803 | Xenbase:XB-GENE-947453 | RATNO25299 | |
| 64805 | Xenbase:XB-GENE-947453 | ||
| 70839 | Xenbase:XB-GENE-947453 | MOUSE38319 | |
| 408007 | BOVIN15157 | ||
| 442958 | CANLF09196 | ||
| 503659 | PIGXX04948 | ||
| 710036 | MACMU28039 | ||
| 100149618 | DANRE08299 | ||
| 100396621 | CALJA15347 | ||
| 100450073 | PONAB26814 |
