GlyCosmos Portal

Submissions

F-box and leucine rich repeat protein 17

Summary

Gene Symbol

FBXL17

Organism

Homo sapiens (human)

External Links

NCBI Gene

64839

PubChem

64839

Alliance of Genome Resources

HGNC:13615

Annotation

Keyword

3D-structure
Alternative splicing
Cytoplasm
Neurogenesis
Nucleus
Reference proteome
Ubl conjugation pathway

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9UF56	F-box and leucine-rich repeat protein 17 F-box only protein 13

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
protein polyubiquitination	IDA	27234298
protein quality control for misfolded or incompletely synthesized proteins	IDA	30190310
nervous system development	ISS
regulation of smoothened signaling pathway	IMP	27234298
neural crest cell differentiation	ISS

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

protein quality control for misfolded or incompletely synthesized proteins

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

protein polyubiquitination

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

catabolic process [inference]

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

protein quality control for misfolded or incompletely synthesized proteins

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

protein polyubiquitination

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

protein quality control for misfolded or incompletely synthesized proteins

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

protein polyubiquitination

macromolecule modification [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

protein polyubiquitination

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

proteolysis involved in protein catabolic process [inference]

protein quality control for misfolded or incompletely synthesized proteins

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

protein polyubiquitination

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

organic substance catabolic process [inference]

macromolecule catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

modification-dependent macromolecule catabolic process [inference]

modification-dependent protein catabolic process [inference]

ubiquitin-dependent protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

organonitrogen compound catabolic process [inference]

protein catabolic process [inference]

proteasomal protein catabolic process [inference]

proteasome-mediated ubiquitin-dependent protein catabolic process

SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

cellular process [inference]

cellular developmental process [inference]

cell differentiation [inference]

mesenchymal cell differentiation [inference]

neural crest cell differentiation

stem cell differentiation [inference]

neural crest cell differentiation

developmental process [inference]

anatomical structure development [inference]

system development [inference]

nervous system development

cellular developmental process [inference]

cell differentiation [inference]

mesenchymal cell differentiation [inference]

neural crest cell differentiation

stem cell differentiation [inference]

neural crest cell differentiation

response to stimulus [inference]

response to external stimulus [inference]

entrainment of circadian clock [inference]

entrainment of circadian clock by photoperiod

response to abiotic stimulus [inference]

response to radiation [inference]

response to light stimulus [inference]

photoperiodism [inference]

entrainment of circadian clock by photoperiod

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of smoothened signaling pathway

regulation of circadian rhythm [inference]

entrainment of circadian clock [inference]

entrainment of circadian clock by photoperiod

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of smoothened signaling pathway

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of smoothened signaling pathway

Displaying entries **1 - 5** of 7 in total

1

2

Next ›

Last »
GO Term	Evidence Code	PMID
nucleus	IDA	24035498 27234298
nucleoplasm	TAS
nucleoplasm	IDA
cytoplasm	IDA	24035498
cytosol

GO Hierarchy

cellular component

protein-containing complex [inference]

intracellular protein-containing complex [inference]

ubiquitin ligase complex [inference]

cullin-RING ubiquitin ligase complex [inference]

SCF ubiquitin ligase complex

catalytic complex [inference]

transferase complex [inference]

ubiquitin ligase complex [inference]

cullin-RING ubiquitin ligase complex [inference]

SCF ubiquitin ligase complex

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying 1 entry
GO Term	Evidence Code	PMID
protein binding	IPI	24035498 27234298 27705803 30190310 33961781 35869491

GO Hierarchy

molecular function

binding [inference]

protein binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

F-box/LRR-repeat protein

Functional Category

K: Transcription
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
SCF-dependent proteasomal ubiquitin-dependent protein catabolic process

Displaying **all 4** entries
InterPro
F-box domain
F-box-like domain superfamily
Leucine-rich repeat domain superfamily
Leucine-rich repeat, cysteine-containing subtype

Ortholog

Displaying entries **1 - 10** of 39 in total

1

2

3

4

Next ›

Last »
Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Mus musculus	50758		MOUSE20485
Danio rerio	64839	ZFIN:ZDB-GENE-111013-3
Drosophila melanogaster	283807	FB:FBgn0031528
Rattus norvegicus	316663		RATNO43274
Pan troglodytes	461980		PANTR35874
Rattus norvegicus	853552	RGD:1309773
Monodelphis domestica	100031220		MONDO17365
Ornithorhynchus anatinus	100082775		ORNAN30513
Equus caballus	100146140		HORSE08175
Callithrix jacchus	100387200		CALJA26002