UPF3B regulator of nonsense mediated mRNA decay

Summary
Gene Symbol
  • UPF3B
Organism
Homo sapiens (human)
NCBI Gene
65109
PubChem
65109
Alliance of Genome Resources
JoGo
UPF3B
TogoVar
UPF3B
Annotation
Keyword
  • 3D-structure
  • Alternative splicing
  • Cytoplasm
  • Disease variant
  • Intellectual disability
  • Methylation
  • Nonsense-mediated mRNA decay
  • Nucleus
  • Phosphoprotein
  • Proteomics identification
  • RNA-binding
  • Reference proteome
  • mRNA transport
Proteins
Displaying 1 entry
UniProt Protein Name
Q9BZI7
  • Nonsense mRNA reducing factor 3B
  • Up-frameshift suppressor 3 homolog B
  • Up-frameshift suppressor 3 homolog on chromosome X
Gene Ontology (GO)
GO Hierarchy
OrthoDB (Group)
Group level
Eukaryota
Group Name
Upf3
Functional Category
  • J: Translation, ribosomal structure and biogenesis
  • K: Transcription
  • T: Signal transduction mechanisms
Disease
Disease Ontology
Displaying 1 entry
DO ID Disease Name Source
DOID:0060821 syndromic X-linked intellectual disability 14

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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Last updated: December 8, 2025