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alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase

Summary

Gene Symbol

Mgat5

Organism

Rattus norvegicus (Norway rat)

External Links

NCBI Gene

65271

KEGG Gene ID

rno:65271

PubChem

65271

Alliance of Genome Resources

RGD:620100

Annotation

Keyword

Direct protein sequencing
Disulfide bond
Glycoprotein
Glycosyltransferase
Golgi apparatus
Reference proteome
Secreted
Signal-anchor
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q08834	Alpha-mannoside beta-1,6-N-acetylglucosaminyltransferase GlcNAc-T V Mannoside acetylglucosaminyltransferase 5 N-acetylglucosaminyl-transferase V
A9CMA3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein N-linked glycosylation via asparagine	IEA ISO ISS
protein N-linked glycosylation	IBA ISO
positive regulation of cell migration	IEA ISO
positive regulation of receptor signaling pathway via STAT	IEA ISO

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

glycosylation [inference]

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

macromolecule modification [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

macromolecule glycosylation [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein glycosylation [inference]

protein N-linked glycosylation

protein N-linked glycosylation via asparagine

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via STAT

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

positive regulation of cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of biological process [inference]

positive regulation of signaling [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

positive regulation of cell motility [inference]

positive regulation of cell migration

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via STAT

positive regulation of response to stimulus [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

regulation of receptor signaling pathway via STAT [inference]

positive regulation of receptor signaling pathway via STAT

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

positive regulation of cellular process [inference]

positive regulation of cell communication [inference]

positive regulation of signal transduction [inference]

positive regulation of receptor signaling pathway via STAT

positive regulation of cell motility [inference]

positive regulation of cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

positive regulation of cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration

Displaying **all 4** entries
GO Term	Evidence Code	PMID
membrane	ISO
Golgi apparatus	IBA ISO
extracellular region	IEA
Golgi membrane	IEA ISS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular region

membrane

organelle membrane [inference]

bounding membrane of organelle [inference]

Golgi membrane

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

Golgi apparatus

Displaying **all 5** entries
GO Term	Evidence Code	PMID
protein phosphatase inhibitor activity	IEA ISO
manganese ion binding	IEA ISO ISS
acetylglucosaminyltransferase activity	ISO
glycosyltransferase activity	ISO
alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity	IBA IEA ISO ISS

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

glycosyltransferase activity

UDP-glycosyltransferase activity [inference]

acetylglucosaminyltransferase activity

alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity

hexosyltransferase activity [inference]

acetylglucosaminyltransferase activity

alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity

catalytic activity, acting on a protein [inference]

catalytic activity, acting on a glycoprotein [inference]

alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding [inference]

transition metal ion binding [inference]

manganese ion binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme inhibitor activity [inference]

phosphatase inhibitor activity [inference]

protein phosphatase inhibitor activity

phosphatase regulator activity [inference]

phosphatase inhibitor activity [inference]

protein phosphatase inhibitor activity

protein phosphatase regulator activity [inference]

protein phosphatase inhibitor activity

molecular function inhibitor activity [inference]

enzyme inhibitor activity [inference]

phosphatase inhibitor activity [inference]

protein phosphatase inhibitor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase A

Functional Category

G: Carbohydrate transport and metabolism
P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 3** entries
Gene Ontology
alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity
protein N-linked glycosylation
transferase activity

Displaying **all 2** entries
InterPro
Domain of unknown function DUF4525
Glycosyltransferase family 18

KEGG BRITE Database

Orthology

K00744

Name

alpha-1,3(6)-mannosylglycoprotein beta-1,6-N-acetyl-glucosaminyltransferase [EC:2.4.1.155]

References

11937505

Reactions

Displaying **all 2** entries
KEGG Reaction	Enzyme	Acceptor	Product
R07622	2.4.1.-	G39213VZ	G10219AA
R05991	2.4.1.155	G29011JC	G20030CU

Rhea

RHEA:16921

UDP-N-acetyl-α-D-glucosamine

H⁺ + UDP

Enzyme

2.4.1.155

PMID

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:576	proteinuria	Alliance of Genome Resources

Ortholog

Displaying entries **51 - 60** of **119** in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Erinaceus europaeus	103122100		ERIEU13617
Callorhinchus milii	103180379		CALMI20223
Chlorocebus sabaeus	103216975		CHLSB01259
Carlito syrichta	103271940		CARSF10333
Ursus maritimus	103667662		URSMA16233
Nannospalax galili	103733594	1026970_0:001520	NANGA13426
Serinus canaria	103814283		SERCA06559
Rhinopithecus roxellana	104654400		RHIRO15255
Fukomys damarensis	104849669	885580_0:0038ff
Macaca nemestrina	105492547		MACNE05059

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

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Summary

External Links

Annotation

OrthoDB (Group)

KEGG BRITE Database

International Collaboration

Acknowledgements