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solute carrier family 7 member 2

Summary

Gene Symbol

SLC7A2

Organism

Homo sapiens (human)

External Links

NCBI Gene

6542

PubChem

6542

Alliance of Genome Resources

HGNC:11060

Annotation

Keyword

Alternative splicing
Amino-acid transport
Cell membrane
Glycoprotein
Phosphoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P52569	Low affinity cationic amino acid transporter 2 Solute carrier family 7 member 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 10** of 11 in total

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GO Term	Evidence Code	PMID
transport across blood-brain barrier	NAS	30280653
L-alpha-amino acid transmembrane transport	IDA	23864433
L-ornithine transmembrane transport	IBA
L-lysine transmembrane transport	IEA
L-arginine transmembrane transport	IDA	9174363

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

import across plasma membrane [inference]

amino acid import across plasma membrane

L-arginine import across plasma membrane

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane

L-arginine import across plasma membrane

L-alpha-amino acid transmembrane transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

multicellular organismal process [inference]

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

vascular transport [inference]

transport across blood-brain barrier

localization [inference]

establishment of localization [inference]

transport [inference]

vascular transport [inference]

transport across blood-brain barrier

transmembrane transport [inference]

import across plasma membrane [inference]

amino acid import across plasma membrane

L-arginine import across plasma membrane

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane

L-arginine import across plasma membrane

L-alpha-amino acid transmembrane transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

organic substance transport [inference]

organic anion transport [inference]

carboxylic acid transport [inference]

amino acid transport

amino acid transmembrane transport [inference]

amino acid import across plasma membrane

L-arginine import across plasma membrane

L-alpha-amino acid transmembrane transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

basic amino acid transport [inference]

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

L-amino acid transport

L-lysine transport [inference]

L-lysine transmembrane transport

L-alpha-amino acid transmembrane transport

ornithine transport [inference]

L-ornithine transmembrane transport

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane

L-arginine import across plasma membrane

L-alpha-amino acid transmembrane transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

organic acid transport [inference]

carboxylic acid transport [inference]

amino acid transport

amino acid transmembrane transport [inference]

amino acid import across plasma membrane

L-arginine import across plasma membrane

L-alpha-amino acid transmembrane transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

basic amino acid transport [inference]

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

L-amino acid transport

L-lysine transport [inference]

L-lysine transmembrane transport

L-alpha-amino acid transmembrane transport

ornithine transport [inference]

L-ornithine transmembrane transport

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane

L-arginine import across plasma membrane

L-alpha-amino acid transmembrane transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane

L-arginine import across plasma membrane

L-alpha-amino acid transmembrane transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

modified amino acid transport [inference]

nitrogen compound transport [inference]

amino acid transport

amino acid transmembrane transport [inference]

amino acid import across plasma membrane

L-arginine import across plasma membrane

L-alpha-amino acid transmembrane transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

basic amino acid transport [inference]

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

L-amino acid transport

L-lysine transport [inference]

L-lysine transmembrane transport

L-alpha-amino acid transmembrane transport

ornithine transport [inference]

L-ornithine transmembrane transport

modified amino acid transport [inference]

import into cell [inference]

amino acid import across plasma membrane

L-arginine import across plasma membrane

Displaying **all 4** entries
GO Term	Evidence Code	PMID
plasma membrane	TAS
plasma membrane	IDA
plasma membrane	IBA
cell junction	IDA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

cell junction

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
L-ornithine transmembrane transporter activity	IBA
amino acid transmembrane transporter activity	TAS
amino acid transmembrane transporter activity	IDA	28684763
basic amino acid transmembrane transporter activity	TAS	8954799
L-amino acid transmembrane transporter activity	IDA	23864433

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

organic acid transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

amino acid transmembrane transporter activity

basic amino acid transmembrane transporter activity

L-amino acid transmembrane transporter activity

organic anion transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

amino acid transmembrane transporter activity

basic amino acid transmembrane transporter activity

L-amino acid transmembrane transporter activity

modified amino acid transmembrane transporter activity [inference]

L-arginine transmembrane transporter activity

salt transmembrane transporter activity [inference]

L-lysine transmembrane transporter activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Permease

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying 1 entry
InterPro
Amino acid permease/ SLC12A domain

Ortholog

Displaying entries **21 - 30** of 94 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Danio rerio	852803	ZFIN:ZDB-GENE-041212-5
Saccharomyces cerevisiae S288C	854530	SGD:S000005875
Saccharomyces cerevisiae S288C	855854	SGD:S000006195
Monodelphis domestica	100021629		MONDO25613
Sus scrofa	100037298		PIGXX11096
Ornithorhynchus anatinus	100078044		ORNAN04245
Taeniopygia guttata	100227076		TAEGU23516
Callithrix jacchus	100397322		CALJA08836
Pongo abelii	100433164		PONAB34858
Ailuropoda melanoleuca	100472779		AILME08122