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solute carrier family 7 member 2

Summary

Gene Symbol

SLC7A2

Organism

Homo sapiens (human)

External Links

NCBI Gene

6542

PubChem

6542

Alliance of Genome Resources

HGNC:11060

Annotation

Keyword

Alternative splicing
Amino-acid transport
Cell membrane
Glycoprotein
Phosphoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P52569	Low affinity cationic amino acid transporter 2 Solute carrier family 7 member 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **6 - 10** of 11 in total

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GO Term	Evidence Code	PMID
transport across blood-brain barrier	NAS	30280653
L-alpha-amino acid transmembrane transport	IDA	23864433
L-ornithine transmembrane transport	IBA
L-lysine transmembrane transport	IEA
L-arginine transmembrane transport	IDA	9174363

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

import across plasma membrane [inference]

amino acid import across plasma membrane

L-arginine import across plasma membrane

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane

L-arginine import across plasma membrane

L-alpha-amino acid transmembrane transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

multicellular organismal process [inference]

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

vascular transport [inference]

transport across blood-brain barrier

localization [inference]

establishment of localization [inference]

transport [inference]

vascular transport [inference]

transport across blood-brain barrier

transmembrane transport [inference]

import across plasma membrane [inference]

amino acid import across plasma membrane

L-arginine import across plasma membrane

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane

L-arginine import across plasma membrane

L-alpha-amino acid transmembrane transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

organic substance transport [inference]

organic anion transport [inference]

carboxylic acid transport [inference]

amino acid transport

amino acid transmembrane transport [inference]

amino acid import across plasma membrane

L-arginine import across plasma membrane

L-alpha-amino acid transmembrane transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

basic amino acid transport [inference]

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

L-amino acid transport

L-lysine transport [inference]

L-lysine transmembrane transport

L-alpha-amino acid transmembrane transport

ornithine transport [inference]

L-ornithine transmembrane transport

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane

L-arginine import across plasma membrane

L-alpha-amino acid transmembrane transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

organic acid transport [inference]

carboxylic acid transport [inference]

amino acid transport

amino acid transmembrane transport [inference]

amino acid import across plasma membrane

L-arginine import across plasma membrane

L-alpha-amino acid transmembrane transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

basic amino acid transport [inference]

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

L-amino acid transport

L-lysine transport [inference]

L-lysine transmembrane transport

L-alpha-amino acid transmembrane transport

ornithine transport [inference]

L-ornithine transmembrane transport

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane

L-arginine import across plasma membrane

L-alpha-amino acid transmembrane transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane

L-arginine import across plasma membrane

L-alpha-amino acid transmembrane transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

modified amino acid transport [inference]

nitrogen compound transport [inference]

amino acid transport

amino acid transmembrane transport [inference]

amino acid import across plasma membrane

L-arginine import across plasma membrane

L-alpha-amino acid transmembrane transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

basic amino acid transport [inference]

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

L-amino acid transport

L-lysine transport [inference]

L-lysine transmembrane transport

L-alpha-amino acid transmembrane transport

ornithine transport [inference]

L-ornithine transmembrane transport

modified amino acid transport [inference]

import into cell [inference]

amino acid import across plasma membrane

L-arginine import across plasma membrane

Displaying **all 4** entries
GO Term	Evidence Code	PMID
plasma membrane	TAS
plasma membrane	IDA
plasma membrane	IBA
cell junction	IDA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

cell junction

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
L-ornithine transmembrane transporter activity	IBA
amino acid transmembrane transporter activity	TAS
amino acid transmembrane transporter activity	IDA	28684763
basic amino acid transmembrane transporter activity	TAS	8954799
L-amino acid transmembrane transporter activity	IDA	23864433

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

organic acid transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

amino acid transmembrane transporter activity

basic amino acid transmembrane transporter activity

L-amino acid transmembrane transporter activity

organic anion transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

amino acid transmembrane transporter activity

basic amino acid transmembrane transporter activity

L-amino acid transmembrane transporter activity

modified amino acid transmembrane transporter activity [inference]

L-arginine transmembrane transporter activity

salt transmembrane transporter activity [inference]

L-lysine transmembrane transporter activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Permease

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying 1 entry
InterPro
Amino acid permease/ SLC12A domain

Ortholog

Displaying entries **31 - 40** of 94 in total

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Species	Gene ID	Orthologous MAtrix
Anolis carolinensis	100562227	ANOCA07578
Nomascus leucogenys	100605714	NOMLE28648
Loxodonta africana	100670720	LOXAF12278
Oreochromis niloticus	100689797	ORENI47673
Cavia porcellus	100734810	CAVPO14675
Cricetulus griseus	100772617	CRIGR03552
Otolemur garnettii	100961880	OTOGA05387
Pan paniscus	100995443	PANPA37738
Papio anubis	101005392	PAPAN39088
Saimiri boliviensis boliviensis	101042507	SAIBB25430