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solute carrier family 7 member 2

Summary

Gene Symbol

SLC7A2

Organism

Homo sapiens (human)

External Links

NCBI Gene

6542

PubChem

6542

Alliance of Genome Resources

HGNC:11060

Annotation

Keyword

Alternative splicing
Amino-acid transport
Cell membrane
Glycoprotein
Phosphoprotein
Reference proteome
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
P52569	Low affinity cationic amino acid transporter 2 Solute carrier family 7 member 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
amino acid transport	TAS
L-amino acid transport	IDA	28684763
amino acid import across plasma membrane	IDA	23864433 28684763
L-arginine import across plasma membrane	IDA	23864433
L-arginine import across plasma membrane	IBA

GO Hierarchy

biological process

cellular process [inference]

transmembrane transport [inference]

import across plasma membrane [inference]

amino acid import across plasma membrane

L-arginine import across plasma membrane

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane

L-arginine import across plasma membrane

L-alpha-amino acid transmembrane transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

multicellular organismal process [inference]

system process [inference]

circulatory system process [inference]

vascular process in circulatory system [inference]

vascular transport [inference]

transport across blood-brain barrier

localization [inference]

establishment of localization [inference]

transport [inference]

vascular transport [inference]

transport across blood-brain barrier

transmembrane transport [inference]

import across plasma membrane [inference]

amino acid import across plasma membrane

L-arginine import across plasma membrane

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane

L-arginine import across plasma membrane

L-alpha-amino acid transmembrane transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

organic substance transport [inference]

organic anion transport [inference]

carboxylic acid transport [inference]

amino acid transport

amino acid transmembrane transport [inference]

amino acid import across plasma membrane

L-arginine import across plasma membrane

L-alpha-amino acid transmembrane transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

basic amino acid transport [inference]

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

L-amino acid transport

L-lysine transport [inference]

L-lysine transmembrane transport

L-alpha-amino acid transmembrane transport

ornithine transport [inference]

L-ornithine transmembrane transport

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane

L-arginine import across plasma membrane

L-alpha-amino acid transmembrane transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

organic acid transport [inference]

carboxylic acid transport [inference]

amino acid transport

amino acid transmembrane transport [inference]

amino acid import across plasma membrane

L-arginine import across plasma membrane

L-alpha-amino acid transmembrane transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

basic amino acid transport [inference]

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

L-amino acid transport

L-lysine transport [inference]

L-lysine transmembrane transport

L-alpha-amino acid transmembrane transport

ornithine transport [inference]

L-ornithine transmembrane transport

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane

L-arginine import across plasma membrane

L-alpha-amino acid transmembrane transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

organic acid transmembrane transport [inference]

carboxylic acid transmembrane transport [inference]

amino acid transmembrane transport [inference]

amino acid import across plasma membrane

L-arginine import across plasma membrane

L-alpha-amino acid transmembrane transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

modified amino acid transport [inference]

nitrogen compound transport [inference]

amino acid transport

amino acid transmembrane transport [inference]

amino acid import across plasma membrane

L-arginine import across plasma membrane

L-alpha-amino acid transmembrane transport

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

basic amino acid transport [inference]

basic amino acid transmembrane transport [inference]

L-arginine transmembrane transport

L-amino acid transport

L-lysine transport [inference]

L-lysine transmembrane transport

L-alpha-amino acid transmembrane transport

ornithine transport [inference]

L-ornithine transmembrane transport

modified amino acid transport [inference]

import into cell [inference]

amino acid import across plasma membrane

L-arginine import across plasma membrane

Displaying **all 4** entries
GO Term	Evidence Code	PMID
plasma membrane	TAS
plasma membrane	IDA
plasma membrane	IBA
cell junction	IDA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

cell junction

Displaying entries **6 - 8** of 8 in total

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GO Term	Evidence Code	PMID
L-lysine transmembrane transporter activity	IBA
L-arginine transmembrane transporter activity	IDA	23864433 9174363
L-arginine transmembrane transporter activity	IBA

GO Hierarchy

molecular function

transporter activity [inference]

transmembrane transporter activity [inference]

organic acid transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

amino acid transmembrane transporter activity

basic amino acid transmembrane transporter activity

L-amino acid transmembrane transporter activity

organic anion transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

amino acid transmembrane transporter activity

basic amino acid transmembrane transporter activity

L-amino acid transmembrane transporter activity

modified amino acid transmembrane transporter activity [inference]

L-arginine transmembrane transporter activity

salt transmembrane transporter activity [inference]

L-lysine transmembrane transporter activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Permease

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
T: Signal transduction mechanisms

Displaying 1 entry
InterPro
Amino acid permease/ SLC12A domain

Ortholog

Displaying entries **81 - 90** of 94 in total

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Species	Gene ID	Orthologous MAtrix
Bos indicus x Bos taurus	113885072	BOBOX26622
Vombatus ursinus	114036905	VOMUR22612
Podarcis muralis	114604602	PODMU29865
Echeneis naucrates	115049498	ECHNA29854
Salmo trutta	115205533	SALTR112827
Salarias fasciatus	115395483	SALFA01335
Gadus morhua	115552795	GADMO01814
Strigops habroptila	115610704	STRHB18934
Corvus moneduloides	116444038	CORMO22109
Chelonoidis abingdonii	116835387	CHEAB12124