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solute carrier family 10 member 1

Summary

Gene Symbol

SLC10A1

Organism

Homo sapiens (human)

External Links

NCBI Gene

6554

PubChem

6554

Alliance of Genome Resources

HGNC:10905

Annotation

Keyword

3D-structure
Cell membrane
Disease variant
Glycoprotein
Host cell receptor for virus entry
Host-virus interaction
Lipid transport
Reference proteome
Sodium transport
Symport
Transmembrane helix

Proteins

Displaying **all 2** entries
UniProt	Protein Name
B2RA41
Q14973	Cell growth-inhibiting gene 29 protein Na(+)/bile acid cotransporter Na(+)/taurocholate transport protein Sodium/taurocholate cotransporting polypeptide Solute carrier family 10 member 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
sodium ion transport	IEA
response to organic cyclic compound
bile acid and bile salt transport	TAS
bile acid and bile salt transport	IBA
response to nutrient levels	IEA

GO Hierarchy

biological process

cellular process [inference]

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to xenobiotic stimulus

transmembrane transport

biological process involved in interspecies interaction between organisms [inference]

biological process involved in symbiotic interaction [inference]

biological process involved in interaction with host [inference]

movement in host [inference]

entry into host [inference]

viral entry into host cell

response to stimulus [inference]

response to external stimulus [inference]

response to extracellular stimulus [inference]

response to nutrient levels

response to endogenous stimulus [inference]

response to hormone [inference]

response to estrogen

response to chemical [inference]

response to xenobiotic stimulus [inference]

cellular response to xenobiotic stimulus

response to organic substance [inference]

response to hormone [inference]

response to estrogen

response to organic cyclic compound

response to alcohol [inference]

response to ethanol

cellular response to chemical stimulus [inference]

cellular response to xenobiotic stimulus

response to oxygen-containing compound [inference]

response to alcohol [inference]

response to ethanol

cellular response to stimulus [inference]

cellular response to chemical stimulus [inference]

cellular response to xenobiotic stimulus

localization [inference]

establishment of localization [inference]

transport [inference]

monoatomic ion transport [inference]

monoatomic cation transport [inference]

metal ion transport [inference]

sodium ion transport

transmembrane transport

organic substance transport [inference]

lipid transport [inference]

bile acid and bile salt transport

organic anion transport [inference]

carboxylic acid transport [inference]

monocarboxylic acid transport [inference]

bile acid and bile salt transport

organic acid transport [inference]

carboxylic acid transport [inference]

monocarboxylic acid transport [inference]

bile acid and bile salt transport

organic hydroxy compound transport [inference]

bile acid and bile salt transport

Displaying **all 3** entries
GO Term	Evidence Code	PMID
plasma membrane	TAS
plasma membrane	IDA	22029531
basolateral plasma membrane	ISS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

plasma membrane region [inference]

basolateral plasma membrane

Displaying **all 5** entries
GO Term	Evidence Code	PMID
virus receptor activity	IEA
protein binding	IPI	32296183
bile acid:sodium symporter activity	TAS
bile acid:sodium symporter activity	IBA
bile acid transmembrane transporter activity	IDA	22029531

GO Hierarchy

molecular function

transporter activity [inference]

lipid transporter activity [inference]

bile acid transmembrane transporter activity

bile acid:sodium symporter activity

transmembrane transporter activity [inference]

organic acid transmembrane transporter activity [inference]

organic acid:sodium symporter activity [inference]

monocarboxylate:sodium symporter activity [inference]

bile acid:sodium symporter activity

carboxylic acid transmembrane transporter activity [inference]

monocarboxylic acid transmembrane transporter activity [inference]

bile acid transmembrane transporter activity

bile acid:sodium symporter activity

secondary active monocarboxylate transmembrane transporter activity [inference]

monocarboxylate:sodium symporter activity [inference]

bile acid:sodium symporter activity

organic anion transmembrane transporter activity [inference]

carboxylic acid transmembrane transporter activity [inference]

monocarboxylic acid transmembrane transporter activity [inference]

bile acid transmembrane transporter activity

bile acid:sodium symporter activity

secondary active monocarboxylate transmembrane transporter activity [inference]

monocarboxylate:sodium symporter activity [inference]

bile acid:sodium symporter activity

monoatomic ion transmembrane transporter activity [inference]

monoatomic cation transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

monocarboxylate:sodium symporter activity [inference]

bile acid:sodium symporter activity

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

monocarboxylate:sodium symporter activity [inference]

bile acid:sodium symporter activity

active monoatomic ion transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

monocarboxylate:sodium symporter activity [inference]

bile acid:sodium symporter activity

inorganic molecular entity transmembrane transporter activity [inference]

inorganic cation transmembrane transporter activity [inference]

metal ion transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

monocarboxylate:sodium symporter activity [inference]

bile acid:sodium symporter activity

active transmembrane transporter activity [inference]

secondary active transmembrane transporter activity [inference]

symporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

monocarboxylate:sodium symporter activity [inference]

bile acid:sodium symporter activity

secondary active monocarboxylate transmembrane transporter activity [inference]

monocarboxylate:sodium symporter activity [inference]

bile acid:sodium symporter activity

active monoatomic ion transmembrane transporter activity [inference]

solute:monoatomic cation symporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

monocarboxylate:sodium symporter activity [inference]

bile acid:sodium symporter activity

organic hydroxy compound transmembrane transporter activity [inference]

bile acid transmembrane transporter activity

bile acid:sodium symporter activity

salt transmembrane transporter activity [inference]

sodium ion transmembrane transporter activity [inference]

solute:sodium symporter activity [inference]

organic acid:sodium symporter activity [inference]

monocarboxylate:sodium symporter activity [inference]

bile acid:sodium symporter activity

binding [inference]

protein binding

exogenous protein binding [inference]

virus receptor activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

sodium/bile acid cotransporter

Functional Category

P: Inorganic ion transport and metabolism
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
bile acid
symporter activity

Displaying **all 3** entries
InterPro
Bile acid
Bile acid
Sodium/solute symporter superfamily

Ortholog

Displaying entries **1 - 10** of 69 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	6554	Xenbase:XB-GENE-6467943
Mus musculus	20493	Xenbase:XB-GENE-6467943	MOUSE09351
Rattus norvegicus	24777	Xenbase:XB-GENE-6467943	RATNO36716
Pan troglodytes	453001		PANTR09053
Canis lupus familiaris	480372		CANLF18036
Bos taurus	532890		BOVIN01627
Macaca mulatta	712925		MACMU40369
Monodelphis domestica	100028851		MONDO02290
Equus caballus	100064290		HORSE22609
Sus scrofa	100153302		PIGXX32741