SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4

Summary
Gene Symbol
  • SMARCA4
Organism
Homo sapiens (human)
NCBI Gene
6597
PubChem
6597
Alliance of Genome Resources
Annotation
Keyword
  • 3D-structure
  • ATP-binding
  • Acetylation
  • Activator
  • Alternative splicing
  • Bromodomain
  • Chromatin regulator
  • Disease variant
  • Helicase
  • Hydrolase
  • Intellectual disability
  • Isopeptide bond
  • Neurogenesis
  • Nucleus
  • Phosphoprotein
  • Proteomics identification
  • RNA-binding
  • Reference proteome
  • Repressor
  • Transcription regulation
  • Ubl conjugation
Proteins
Displaying all 4 entries
UniProt Protein Name
P51532
  • ATP-dependent helicase SMARCA4
  • BRG1-associated factor 190A
  • Mitotic growth and transcription activator
  • Protein BRG-1
  • Protein brahma homolog 1
  • SNF2-beta
  • SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4
Q9HBD4
A7E2E1
B3KNW7
Gene Ontology (GO)
GO Hierarchy
GO Hierarchy
OrthoDB (Group)
Group level
Eukaryota
Group Name
ATP-dependent helicase
Functional Category
  • L: Replication, recombination and repair
  • O: Posttranslational modification, protein turnover, chaperones
  • T: Signal transduction mechanisms
Displaying all 2 entries
InterPro
Bromodomain-like superfamily
Bromodomain
Disease
Disease Ontology
Displaying all 4 entries
DO ID Disease Name Source
DOID:0060997 rhabdoid tumor predisposition syndrome 2
DOID:0070046 Coffin-Siris syndrome 4
DOID:3908 lung non-small cell carcinoma
DOID:684 hepatocellular carcinoma

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Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01


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