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tyrosine-protein kinase-like otk

Summary

Gene Symbol

LOC6608743

Organism

Drosophila sechellia

External Links

NCBI Gene: 6608743
PubChem: 6608743

Annotation

Keyword

Cell adhesion
Cell membrane
Disulfide bond
Glycoprotein
Immunoglobulin domain
Neurogenesis
Phosphoprotein
Receptor
Reference proteome
Repeat
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
B4HNW4	Tyrosine-protein kinase-like 7 homolog

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
protein phosphorylation	IEA	22301074
negative regulation of canonical Wnt signaling pathway
dendrite self-avoidance	IEA	30032202
retinal ganglion cell axon guidance
homophilic cell adhesion via plasma membrane adhesion molecules	IEA	30032202

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

macromolecule modification [inference]

protein modification process [inference]

protein phosphorylation

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

protein phosphorylation

cellular process [inference]

cell adhesion

cell-cell adhesion [inference]

cell-cell adhesion via plasma-membrane adhesion molecules [inference]

homophilic cell adhesion via plasma membrane adhesion molecules

cell recognition [inference]

neuron recognition [inference]

dendrite self-avoidance

cellular metabolic process [inference]

phosphorus metabolic process [inference]

phosphate-containing compound metabolic process [inference]

phosphorylation [inference]

protein phosphorylation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

plasma membrane bounded cell projection organization [inference]

neuron projection development [inference]

neuron projection guidance [inference]

axon guidance

reproductive process [inference]

developmental process involved in reproduction [inference]

genitalia morphogenesis [inference]

post-embryonic genitalia morphogenesis [inference]

imaginal disc-derived genitalia morphogenesis [inference]

internal genitalia morphogenesis

female genitalia morphogenesis [inference]

imaginal disc-derived female genitalia morphogenesis

male genitalia morphogenesis [inference]

imaginal disc-derived male genitalia morphogenesis

male anatomical structure morphogenesis [inference]

male genitalia morphogenesis [inference]

imaginal disc-derived male genitalia morphogenesis

developmental process [inference]

developmental process involved in reproduction [inference]

genitalia morphogenesis [inference]

post-embryonic genitalia morphogenesis [inference]

imaginal disc-derived genitalia morphogenesis [inference]

internal genitalia morphogenesis

female genitalia morphogenesis [inference]

imaginal disc-derived female genitalia morphogenesis

male genitalia morphogenesis [inference]

imaginal disc-derived male genitalia morphogenesis

male anatomical structure morphogenesis [inference]

male genitalia morphogenesis [inference]

imaginal disc-derived male genitalia morphogenesis

anatomical structure morphogenesis [inference]

animal organ morphogenesis [inference]

genitalia morphogenesis [inference]

post-embryonic genitalia morphogenesis [inference]

imaginal disc-derived genitalia morphogenesis [inference]

internal genitalia morphogenesis

female genitalia morphogenesis [inference]

imaginal disc-derived female genitalia morphogenesis

male genitalia morphogenesis [inference]

imaginal disc-derived male genitalia morphogenesis

male anatomical structure morphogenesis [inference]

male genitalia morphogenesis [inference]

imaginal disc-derived male genitalia morphogenesis

biological regulation [inference]

regulation of biological process [inference]

regulation of signaling [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

regulation of Wnt signaling pathway [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

regulation of canonical Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

negative regulation of biological process [inference]

negative regulation of signaling [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

regulation of Wnt signaling pathway [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

regulation of canonical Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

negative regulation of response to stimulus [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

regulation of cellular process [inference]

regulation of cell communication [inference]

regulation of signal transduction [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

regulation of Wnt signaling pathway [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

regulation of canonical Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

negative regulation of cellular process [inference]

negative regulation of cell communication [inference]

negative regulation of signal transduction [inference]

negative regulation of Wnt signaling pathway [inference]

negative regulation of canonical Wnt signaling pathway

Displaying **all 2** entries
GO Term	Evidence Code	PMID
plasma membrane	IEA	30032202
axon	IEA	30032202

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

plasma membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

neuron projection [inference]

axon

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
protein heterodimerization activity
transmembrane receptor protein tyrosine kinase activity
protein tyrosine kinase activity	IEA	22301074
signaling receptor activity
Wnt-protein binding

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring phosphorus-containing groups [inference]

kinase activity [inference]

protein kinase activity

protein tyrosine kinase activity

transmembrane receptor protein tyrosine kinase activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

phosphotransferase activity, alcohol group as acceptor [inference]

protein kinase activity

protein tyrosine kinase activity

transmembrane receptor protein tyrosine kinase activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

catalytic activity, acting on a protein [inference]

protein kinase activity

protein tyrosine kinase activity

transmembrane receptor protein tyrosine kinase activity

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

binding [inference]

protein binding [inference]

Wnt-protein binding

identical protein binding [inference]

protein homodimerization activity

protein dimerization activity [inference]

cell adhesion molecule binding

cell adhesion mediator activity [inference]

cell-cell adhesion mediator activity

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

molecular transducer activity [inference]

signaling receptor activity

transmembrane signaling receptor activity [inference]

transmembrane receptor protein kinase activity [inference]

transmembrane receptor protein tyrosine kinase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Drosophila

Group Name

tyrosine-protein kinase-like otk

Functional Category

M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying entries **1 - 10** of 15 in total

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Gene Ontology
ATP binding
Wnt-protein binding
anatomical structure morphogenesis
animal organ development
cell adhesion molecule binding
imaginal disc-derived female genitalia morphogenesis
imaginal disc-derived male genitalia morphogenesis
internal genitalia morphogenesis
neurogenesis
photoreceptor cell axon guidance

Displaying entries **1 - 10** of 11 in total

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InterPro
Immunoglobulin I-set
Immunoglobulin subtype 2
Immunoglobulin subtype
Immunoglobulin-like domain superfamily
Immunoglobulin-like domain
Immunoglobulin-like fold
Protein kinase domain
Protein kinase-like domain superfamily
Serine-threonine/tyrosine-protein kinase, catalytic domain
Tyrosine-protein kinase, active site

Ortholog

Displaying entries **21 - 30** of 37 in total

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Species	Gene ID	OrthoDB
Drosophila miranda	108160333	7229_1:0024ad
Drosophila busckii	108597281	30019_1:0009f7
Drosophila arizonae	108614991	7263_1:001e44
Drosophila navojoa	108654652	7232_1:000827
Drosophila serrata	110176344	7274_0:000acf
Drosophila obscura	111078517	7282_1:00193b
Drosophila hydei	111595405	7224_1:000729
Drosophila novamexicana	115757815	47314_0:000a80
Drosophila mauritiana	117136272	7226_0:00248c
Drosophila albomicans	117569775	7291_1:001341