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DIM1 rRNA methyltransferase and ribosome maturation factor

Summary

Gene Symbol

Dimt1

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

66254

PubChem

66254

Alliance of Genome Resources

MGI:1913504

Annotation

Keyword

Methyltransferase
Nucleus
RNA-binding
Reference proteome
S-adenosyl-L-methionine
rRNA processing

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9D0D4	18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase 18S rRNA dimethylase DIM1 dimethyladenosine transferase 1 homolog DIM1 dimethyladenosine transferase 1-like S-adenosylmethionine-6-N',N'-adenosyl(rRNA) dimethyltransferase

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 7 in total

1

2

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GO Term	Evidence Code	PMID
rRNA methylation	ISS
rRNA methylation	ISO
rRNA methylation	IBA
ribosomal small subunit biogenesis	ISS
ribosomal small subunit biogenesis	ISO

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

RNA modification [inference]

rRNA modification [inference]

rRNA methylation

RNA methylation [inference]

rRNA methylation

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

methylation [inference]

macromolecule methylation [inference]

RNA methylation [inference]

rRNA methylation

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

RNA modification [inference]

rRNA modification [inference]

rRNA methylation

RNA methylation [inference]

rRNA methylation

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

RNA modification [inference]

rRNA modification [inference]

rRNA methylation

RNA methylation [inference]

rRNA methylation

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

RNA modification [inference]

rRNA modification [inference]

rRNA methylation

RNA methylation [inference]

rRNA methylation

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

RNA modification [inference]

rRNA modification [inference]

rRNA methylation

RNA methylation [inference]

rRNA methylation

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule modification [inference]

RNA modification [inference]

rRNA modification [inference]

rRNA methylation

RNA methylation [inference]

rRNA methylation

macromolecule methylation [inference]

RNA methylation [inference]

rRNA methylation

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

RNA modification [inference]

rRNA modification [inference]

rRNA methylation

RNA methylation [inference]

rRNA methylation

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

RNA modification [inference]

rRNA modification [inference]

rRNA methylation

RNA methylation [inference]

rRNA methylation

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

RNA modification [inference]

rRNA modification [inference]

rRNA methylation

RNA methylation [inference]

rRNA methylation

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

RNA modification [inference]

rRNA modification [inference]

rRNA methylation

RNA methylation [inference]

rRNA methylation

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

RNA modification [inference]

rRNA modification [inference]

rRNA methylation

RNA methylation [inference]

rRNA methylation

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

ncRNA processing [inference]

rRNA processing [inference]

rRNA modification [inference]

rRNA methylation

cellular component organization or biogenesis [inference]

cellular component biogenesis [inference]

ribonucleoprotein complex biogenesis [inference]

ribosomal small subunit biogenesis

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of rRNA processing [inference]

positive regulation of rRNA processing

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

positive regulation of cellular metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of rRNA processing [inference]

positive regulation of rRNA processing

positive regulation of cellular metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of rRNA processing [inference]

positive regulation of rRNA processing

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of rRNA processing [inference]

positive regulation of rRNA processing

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of rRNA processing [inference]

positive regulation of rRNA processing

positive regulation of macromolecule metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of rRNA processing [inference]

positive regulation of rRNA processing

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of rRNA processing [inference]

positive regulation of rRNA processing

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of macromolecule metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

positive regulation of cellular metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of rRNA processing [inference]

positive regulation of rRNA processing

positive regulation of cellular metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of rRNA processing [inference]

positive regulation of rRNA processing

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of rRNA processing

Displaying entries **1 - 5** of 9 in total

1

2

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GO Term	Evidence Code	PMID
nucleoplasm	ISO
nucleoplasm	IEA
nucleolus	ISS
nucleolus	ISO
nucleolus	IBA

GO Hierarchy

cellular component

protein-containing complex [inference]

ribonucleoprotein complex [inference]

preribosome [inference]

small-subunit processome

cellular anatomical entity [inference]

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

nucleolus

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

nucleolus

Displaying **all 5** entries
GO Term	Evidence Code	PMID
rRNA (adenine-N6,N6-)-dimethyltransferase activity	ISO
rRNA (adenine-N6,N6-)-dimethyltransferase activity	IBA
RNA binding	IEA
18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity	ISS
18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity	ISO

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

transferase activity, transferring one-carbon groups [inference]

methyltransferase activity [inference]

N-methyltransferase activity [inference]

rRNA (adenine-N6,N6-)-dimethyltransferase activity

18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity

RNA methyltransferase activity [inference]

rRNA methyltransferase activity [inference]

rRNA (adenine) methyltransferase activity [inference]

rRNA (adenine-N6,N6-)-dimethyltransferase activity

18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity

S-adenosylmethionine-dependent methyltransferase activity [inference]

rRNA methyltransferase activity [inference]

rRNA (adenine) methyltransferase activity [inference]

rRNA (adenine-N6,N6-)-dimethyltransferase activity

18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity

catalytic activity, acting on a nucleic acid [inference]

catalytic activity, acting on RNA [inference]

RNA methyltransferase activity [inference]

rRNA methyltransferase activity [inference]

rRNA (adenine) methyltransferase activity [inference]

rRNA (adenine-N6,N6-)-dimethyltransferase activity

18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity

catalytic activity, acting on a rRNA [inference]

rRNA methyltransferase activity [inference]

rRNA (adenine) methyltransferase activity [inference]

rRNA (adenine-N6,N6-)-dimethyltransferase activity

18S rRNA (adenine(1779)-N(6)/adenine(1780)-N(6))-dimethyltransferase activity

binding [inference]

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

rRNA adenine N(6)-methyltransferase

Functional Category

I: Lipid transport and metabolism
J: Translation, ribosomal structure and biogenesis
Q: Secondary metabolites biosynthesis, transport and catabolism

Displaying **all 5** entries
Gene Ontology
S-adenosylmethionine-dependent methyltransferase activity
methylation
rRNA methylation
rRNA methyltransferase activity
transferase activity

Displaying **all 5** entries
InterPro
Ribosomal RNA adenine dimethylase
Ribosomal RNA adenine methylase transferase, N-terminal
Ribosomal RNA adenine methylase transferase, conserved site
Ribosomal RNA adenine methyltransferase KsgA/Erm
S-adenosyl-L-methionine-dependent methyltransferase superfamily

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

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Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements