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Guidelines

MIRAGE

small nuclear ribonucleoprotein polypeptide A

Summary

Gene Symbol

SNRPA

Organism

Homo sapiens (human)

External Links

NCBI Gene

6626

PubChem

6626

Alliance of Genome Resources

HGNC:11151

Annotation

Keyword

3D-structure
Acetylation
Direct protein sequencing
Methylation
Nucleus
Phosphoprotein
Proteomics identification
RNA-binding
Reference proteome
Repeat
Ribonucleoprotein
Spliceosome

Proteins

Displaying 1 entry
UniProt	Protein Name
P09012

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 3** entries
GO Term	Evidence Code	PMID
mRNA splicing, via spliceosome	NAS	30975767 33677607
mRNA splicing, via spliceosome	IC	9731529
mRNA splicing, via spliceosome	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing [inference]

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing [inference]

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing [inference]

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing [inference]

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing [inference]

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing [inference]

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing [inference]

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing [inference]

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing [inference]

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing [inference]

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
nucleus	NAS	21113136 30975767
nucleoplasm	TAS
nucleoplasm	IDA
spliceosomal complex	IDA	9731529
spliceosomal complex	IPI	33677607

GO Hierarchy

cellular component

protein-containing complex [inference]

Sm-like protein family complex [inference]

small nuclear ribonucleoprotein complex [inference]

spliceosomal snRNP complex [inference]

U1 snRNP

spliceosomal tri-snRNP complex [inference]

U4/U6 x U5 tri-snRNP complex

nuclear protein-containing complex [inference]

spliceosomal complex

small nuclear ribonucleoprotein complex [inference]

spliceosomal snRNP complex [inference]

U1 snRNP

spliceosomal tri-snRNP complex [inference]

U4/U6 x U5 tri-snRNP complex

ribonucleoprotein complex [inference]

spliceosomal complex

small nuclear ribonucleoprotein complex [inference]

spliceosomal snRNP complex [inference]

U1 snRNP

spliceosomal tri-snRNP complex [inference]

U4/U6 x U5 tri-snRNP complex

cellular anatomical entity [inference]

nucleoplasm

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying entries **1 - 5** of 8 in total

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GO Term	Evidence Code	PMID
DNA binding	EXP	8609632
RNA binding	IDA	19561594
RNA binding	HDA	22681889
protein binding	IPI	10688667 12486009 15105431 16189514 22365833 23793891 25416956 29892012 30021884 30886144 31515488 32296183 35271311 39251607 9848648
U1 snRNA binding	IDA	2147232

GO Hierarchy

molecular function

binding [inference]

protein binding

identical protein binding

protein-containing complex binding [inference]

ribonucleoprotein complex binding [inference]

snRNP binding [inference]

U1 snRNP binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

DNA binding

snRNA binding [inference]

U1 snRNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

u1 small nuclear ribonucleoprotein a

Functional Category

J: Translation, ribosomal structure and biogenesis
K: Transcription
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
U1 snRNA binding
mRNA processing

Displaying **all 5** entries
InterPro
Nucleotide-binding alpha-beta plait domain superfamily
RNA recognition motif domain
RNA-binding domain superfamily
U1 small nuclear ribonucleoprotein A, RNA recognition motif 1
U1 small nuclear ribonucleoprotein A, RNA recognition motif 2

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:65	connective tissue disease	Alliance of Genome Resources

Ortholog

Displaying entries **21 - 30** of 78 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Cricetulus griseus	100764569		CRIGR13863
Otolemur garnettii	100954572		OTOGA01553
Pan paniscus	100987526		PANPA20535
Papio anubis	100997801		PAPAN22545
Saimiri boliviensis boliviensis	101044166		SAIBB37727
Takifugu rubripes	101070822		TAKRU04432
Felis catus	101090818		FELCA33726
Oryzias latipes	101155621		ORYLA03366
Octodon degus	101574778		OCTDE26561
Octodon degus	101578836		OCTDE26561

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: December 8, 2025