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small nuclear ribonucleoprotein D1 polypeptide

Summary

Gene Symbol

SNRPD1

Organism

Homo sapiens (human)

External Links

NCBI Gene

6632

PubChem

6632

Alliance of Genome Resources

HGNC:11158

Annotation

Keyword

3D-structure
Cytoplasm
Direct protein sequencing
Isopeptide bond
Methylation
Nucleus
Reference proteome
Repeat
Ribonucleoprotein
Spliceosome
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
P62314	Sm-D autoantigen snRNP core protein D1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
spliceosomal complex assembly	TAS	7527560
spliceosomal snRNP assembly	IDA	18984161
spliceosomal snRNP assembly	IBA
mRNA splicing, via spliceosome	NAS	15564372 30975767 31744343 33677607
mRNA splicing, via spliceosome	IC	11991638

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

RNA capping [inference]

7-methylguanosine cap hypermethylation

RNA modification [inference]

RNA methylation [inference]

7-methylguanosine cap hypermethylation

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

methylation [inference]

macromolecule methylation [inference]

RNA methylation [inference]

7-methylguanosine cap hypermethylation

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

RNA capping [inference]

7-methylguanosine cap hypermethylation

RNA modification [inference]

RNA methylation [inference]

7-methylguanosine cap hypermethylation

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

RNA capping [inference]

7-methylguanosine cap hypermethylation

RNA modification [inference]

RNA methylation [inference]

7-methylguanosine cap hypermethylation

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

RNA capping [inference]

7-methylguanosine cap hypermethylation

RNA modification [inference]

RNA methylation [inference]

7-methylguanosine cap hypermethylation

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

RNA capping [inference]

7-methylguanosine cap hypermethylation

RNA modification [inference]

RNA methylation [inference]

7-methylguanosine cap hypermethylation

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule modification [inference]

RNA modification [inference]

RNA methylation [inference]

7-methylguanosine cap hypermethylation

macromolecule methylation [inference]

RNA methylation [inference]

7-methylguanosine cap hypermethylation

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

RNA capping [inference]

7-methylguanosine cap hypermethylation

RNA modification [inference]

RNA methylation [inference]

7-methylguanosine cap hypermethylation

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

RNA capping [inference]

7-methylguanosine cap hypermethylation

RNA modification [inference]

RNA methylation [inference]

7-methylguanosine cap hypermethylation

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

RNA capping [inference]

7-methylguanosine cap hypermethylation

RNA modification [inference]

RNA methylation [inference]

7-methylguanosine cap hypermethylation

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

RNA capping [inference]

7-methylguanosine cap hypermethylation

RNA modification [inference]

RNA methylation [inference]

7-methylguanosine cap hypermethylation

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

RNA capping [inference]

7-methylguanosine cap hypermethylation

RNA modification [inference]

RNA methylation [inference]

7-methylguanosine cap hypermethylation

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein-RNA complex assembly [inference]

spliceosomal complex assembly

U2-type prespliceosome assembly

spliceosomal snRNP assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein-RNA complex assembly [inference]

spliceosomal complex assembly

U2-type prespliceosome assembly

spliceosomal snRNP assembly

protein-RNA complex organization [inference]

protein-RNA complex assembly [inference]

spliceosomal complex assembly

U2-type prespliceosome assembly

spliceosomal snRNP assembly

Displaying entries **1 - 5** of 37 in total

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GO Term	Evidence Code	PMID
commitment complex	IBA
nucleus	NAS	21113136 30975767 31744343
nucleus	IDA	14524621 28076346
nucleus	IMP	14524621
nucleus	HDA	21630459

GO Hierarchy

cellular component

protein-containing complex [inference]

Sm-like protein family complex [inference]

small nuclear ribonucleoprotein complex

spliceosomal snRNP complex [inference]

spliceosomal tri-snRNP complex

U4/U6 x U5 tri-snRNP complex

nuclear protein-containing complex [inference]

spliceosomal complex

U2-type spliceosomal complex

U12-type spliceosomal complex

precatalytic spliceosome

U2-type precatalytic spliceosome

catalytic step 2 spliceosome

U2-type catalytic step 2 spliceosome

small nuclear ribonucleoprotein complex

spliceosomal snRNP complex [inference]

spliceosomal tri-snRNP complex

U4/U6 x U5 tri-snRNP complex

catalytic complex [inference]

catalytic step 2 spliceosome

U2-type catalytic step 2 spliceosome

transferase complex [inference]

methyltransferase complex [inference]

methylosome

ribonucleoprotein complex [inference]

spliceosomal complex

U2-type spliceosomal complex

U12-type spliceosomal complex

precatalytic spliceosome

U2-type precatalytic spliceosome

catalytic step 2 spliceosome

U2-type catalytic step 2 spliceosome

small nuclear ribonucleoprotein complex

spliceosomal snRNP complex [inference]

spliceosomal tri-snRNP complex

U4/U6 x U5 tri-snRNP complex

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

Displaying **all 4** entries
GO Term	Evidence Code	PMID
RNA binding	IBA
RNA binding	HDA	22658674 22681889
protein binding	IPI	10500148 11135666 11714716 14524621 15939020 17332742 18984161 19928837 21816274 22365833 24981860 25416956 30021884 31799625 32296183 35271311 9417867
U1 snRNP binding	IEA

GO Hierarchy

molecular function

binding [inference]

protein binding

protein-containing complex binding [inference]

ribonucleoprotein complex binding [inference]

snRNP binding [inference]

U1 snRNP binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Small nuclear ribonucleoprotein

Functional Category

K: Transcription
O: Posttranslational modification, protein turnover, chaperones
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
mRNA processing
spliceosomal snRNP assembly

Displaying **all 5** entries
InterPro
LSM domain superfamily
Like-Sm (LSM) domain containing protein, LSm4/SmD1/SmD3
Sm domain, eukaryotic/archaea-type
Sm domain
Small nuclear ribonucleoprotein D1

Disease

Disease Ontology

Displaying **all 4** entries
DO ID	Disease Name	Source
DOID:10952	nephritis	Alliance of Genome Resources
DOID:576	proteinuria	Alliance of Genome Resources
DOID:65	connective tissue disease	Alliance of Genome Resources
DOID:9074	systemic lupus erythematosus	Alliance of Genome Resources

Ortholog

Displaying entries **1 - 10** of 96 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Xenopus tropicalis	6632	Xenbase:XB-GENE-5789948
Mus musculus	20641		MOUSE24835
Danio rerio	192331		DANRE15050
Rattus norvegicus	291794		RATNO13425
Pan troglodytes	455329		PANTR15984
Canis lupus familiaris	480178		CANLF17594
Bos taurus	508788		BOVIN19561
Macaca mulatta	698965		MACMU17380
Monodelphis domestica	100011347		MONDO19801
Equus caballus	100060367		HORSE41915