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small nuclear ribonucleoprotein D2 polypeptide

Summary

Gene Symbol

SNRPD2

Organism

Homo sapiens (human)

External Links

NCBI Gene

6633

PubChem

6633

Alliance of Genome Resources

HGNC:11159

Annotation

Keyword

3D-structure
Acetylation
Alternative splicing
Cytoplasm
Direct protein sequencing
Isopeptide bond
Nucleus
Phosphoprotein
Reference proteome
Ribonucleoprotein
Spliceosome
Ubl conjugation

Proteins

Displaying 1 entry
UniProt	Protein Name
P62316	snRNP core protein D2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
7-methylguanosine cap hypermethylation	NAS	15564372
spliceosomal complex assembly	TAS	7527560
RNA splicing	TAS	1701240
mRNA splicing, via spliceosome	IC IDA NAS	11991638 15564372 28076346 30975767 31744343 32494006 33677607 36797247
U2-type prespliceosome assembly	NAS	31744343

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

RNA capping [inference]

7-methylguanosine cap hypermethylation

RNA modification [inference]

RNA methylation [inference]

7-methylguanosine cap hypermethylation

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

methylation [inference]

macromolecule methylation [inference]

RNA methylation [inference]

7-methylguanosine cap hypermethylation

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

RNA capping [inference]

7-methylguanosine cap hypermethylation

RNA modification [inference]

RNA methylation [inference]

7-methylguanosine cap hypermethylation

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

RNA capping [inference]

7-methylguanosine cap hypermethylation

RNA modification [inference]

RNA methylation [inference]

7-methylguanosine cap hypermethylation

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

RNA capping [inference]

7-methylguanosine cap hypermethylation

RNA modification [inference]

RNA methylation [inference]

7-methylguanosine cap hypermethylation

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

RNA capping [inference]

7-methylguanosine cap hypermethylation

RNA modification [inference]

RNA methylation [inference]

7-methylguanosine cap hypermethylation

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

macromolecule modification [inference]

RNA modification [inference]

RNA methylation [inference]

7-methylguanosine cap hypermethylation

macromolecule methylation [inference]

RNA methylation [inference]

7-methylguanosine cap hypermethylation

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

RNA capping [inference]

7-methylguanosine cap hypermethylation

RNA modification [inference]

RNA methylation [inference]

7-methylguanosine cap hypermethylation

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

RNA capping [inference]

7-methylguanosine cap hypermethylation

RNA modification [inference]

RNA methylation [inference]

7-methylguanosine cap hypermethylation

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

RNA capping [inference]

7-methylguanosine cap hypermethylation

RNA modification [inference]

RNA methylation [inference]

7-methylguanosine cap hypermethylation

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

RNA capping [inference]

7-methylguanosine cap hypermethylation

RNA modification [inference]

RNA methylation [inference]

7-methylguanosine cap hypermethylation

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

RNA splicing

RNA splicing, via transesterification reactions [inference]

RNA splicing, via transesterification reactions with bulged adenosine as nucleophile [inference]

mRNA splicing, via spliceosome

RNA capping [inference]

7-methylguanosine cap hypermethylation

RNA modification [inference]

RNA methylation [inference]

7-methylguanosine cap hypermethylation

mRNA metabolic process [inference]

mRNA processing [inference]

mRNA splicing, via spliceosome

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein-RNA complex assembly [inference]

spliceosomal complex assembly

U2-type prespliceosome assembly

spliceosomal snRNP assembly

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein-RNA complex assembly [inference]

spliceosomal complex assembly

U2-type prespliceosome assembly

spliceosomal snRNP assembly

protein-RNA complex organization [inference]

protein-RNA complex assembly [inference]

spliceosomal complex assembly

U2-type prespliceosome assembly

spliceosomal snRNP assembly

Displaying entries **11 - 15** of 20 in total

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GO Term	Evidence Code	PMID
nucleoplasm	TAS
SMN-Sm protein complex	IDA	18984161
U1 snRNP	IBA IDA IPI NAS	15564372 21113136 25555158 33677607
U2-type precatalytic spliceosome	IDA	28781166
U12-type spliceosomal complex	IDA	15146077

GO Hierarchy

cellular component

protein-containing complex [inference]

Sm-like protein family complex [inference]

small nuclear ribonucleoprotein complex

spliceosomal snRNP complex [inference]

spliceosomal tri-snRNP complex [inference]

U4/U6 x U5 tri-snRNP complex

nuclear protein-containing complex [inference]

spliceosomal complex

U2-type spliceosomal complex

U12-type spliceosomal complex

precatalytic spliceosome

U2-type precatalytic spliceosome

catalytic step 2 spliceosome

U2-type catalytic step 2 spliceosome

small nuclear ribonucleoprotein complex

spliceosomal snRNP complex [inference]

spliceosomal tri-snRNP complex [inference]

U4/U6 x U5 tri-snRNP complex

catalytic complex [inference]

catalytic step 2 spliceosome

U2-type catalytic step 2 spliceosome

transferase complex [inference]

methyltransferase complex [inference]

methylosome

ribonucleoprotein complex [inference]

spliceosomal complex

U2-type spliceosomal complex

U12-type spliceosomal complex

precatalytic spliceosome

U2-type precatalytic spliceosome

catalytic step 2 spliceosome

U2-type catalytic step 2 spliceosome

small nuclear ribonucleoprotein complex

spliceosomal snRNP complex [inference]

spliceosomal tri-snRNP complex [inference]

U4/U6 x U5 tri-snRNP complex

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular membrane-bounded organelle [inference]

nucleus

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

extracellular organelle [inference]

extracellular membrane-bounded organelle [inference]

extracellular vesicle [inference]

extracellular exosome

Displaying **all 2** entries
GO Term	Evidence Code	PMID
protein binding	IPI	10500148 11714716 11748230 12065586 14667819 15231747 15848170 15939020 17332742 18984161 22365833 25416956 28514442 30021884 31799625 32296183 32814053 33961781 35271311 9417867
RNA binding	HDA	22658674

GO Hierarchy

molecular function

binding [inference]

protein binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Small nuclear ribonucleoprotein Sm D2

Functional Category

K: Transcription
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
mRNA processing
spliceosomal snRNP assembly

Displaying **all 4** entries
InterPro
LSM domain superfamily
Sm domain, eukaryotic/archaea-type
Sm domain
Small nuclear ribonucleoprotein Sm D2

Disease

Disease Ontology

Displaying 1 entry
DO ID	Disease Name	Source
DOID:9074	systemic lupus erythematosus	Alliance of Genome Resources

Ortholog

Displaying entries **41 - 50** of **119** in total

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Species	Gene ID	OrthoDB	Orthologous MAtrix
Felis catus	101093907		FELCA32875
Ovis aries	101114635		SHEEP05553
Gorilla gorilla gorilla	101131111	9595_0:004d27	GORGO16730
Oryzias latipes	101158296		ORYLA03670
Tursiops truncatus	101325324		TURTR08507
Octodon degus	101583473		OCTDE18396
Octodon degus	101592471		OCTDE18396
Jaculus jaculus	101611182		JACJA25007
Mustela putorius furo	101686804		MUSPF07009
Heterocephalus glaber	101706238		HETGA11121