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signal peptide peptidase like 2A

Summary

Gene Symbol

Sppl2a

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

66552

PubChem

66552

Alliance of Genome Resources

MGI:1913802

Annotation

Keyword

Endosome
Glycoprotein
Lysosome
Protease
Reference proteome
Signal
Transmembrane helix

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9JJF9	Intramembrane protease 3 Presenilin-like protein 2

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 11 in total

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GO Term	Evidence Code	PMID
membrane protein ectodomain proteolysis	ISS
membrane protein ectodomain proteolysis	ISO
membrane protein intracellular domain proteolysis	ISS
membrane protein intracellular domain proteolysis	ISO
membrane protein proteolysis	ISS

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

membrane protein proteolysis

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

membrane protein proteolysis

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

membrane protein proteolysis

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

membrane protein proteolysis

biological regulation [inference]

regulation of biological process [inference]

regulation of immune system process [inference]

regulation of immune response

regulation of response to stimulus [inference]

regulation of immune response

Displaying entries **6 - 10** of 17 in total

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GO Term	Evidence Code	PMID
membrane	ISO
Golgi-associated vesicle membrane	ISS
Golgi-associated vesicle membrane	ISO
Golgi-associated vesicle membrane	IBA
late endosome membrane	IDA	21896273

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane

plasma membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane [inference]

late endosome membrane

Golgi-associated vesicle membrane

bounding membrane of organelle [inference]

vacuolar membrane [inference]

lytic vacuole membrane [inference]

lysosomal membrane

endosome membrane [inference]

late endosome membrane

Golgi-associated vesicle membrane

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome

intracellular membrane-bounded organelle

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome

intracellular organelle [inference]

intracellular membrane-bounded organelle

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome [inference]

late endosome

side of membrane [inference]

cytoplasmic side of membrane [inference]

cytoplasmic side of endoplasmic reticulum membrane

lumenal side of membrane [inference]

lumenal side of endoplasmic reticulum membrane

Displaying **all 5** entries
GO Term	Evidence Code	PMID
aspartic endopeptidase activity, intramembrane cleaving	ISS
aspartic endopeptidase activity, intramembrane cleaving	ISO
aspartic endopeptidase activity, intramembrane cleaving	IBA
protein homodimerization activity	ISS
protein homodimerization activity	ISO