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Guidelines

MIRAGE

fucosidase, alpha-L- 2, plasma

Summary

Gene Symbol

Fuca2

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

66848

PubChem

66848

Alliance of Genome Resources

MGI:1914098

Annotation

Keyword

Glycoprotein
Glycosidase
Phosphoprotein
Reference proteome
Secreted
Signal

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q99KR8	Alpha-L-fucoside fucohydrolase 2
Q505Q3

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 10 in total

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2

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GO Term	Evidence Code	PMID
fucose metabolic process	ISO
fucose metabolic process	IBA
fucose metabolic process	IEA
response to bacterium	ISO
response to bacterium	IEA

GO Hierarchy

biological process

metabolic process [inference]

catabolic process [inference]

organic substance catabolic process [inference]

carbohydrate derivative catabolic process [inference]

glycosyl compound catabolic process [inference]

glycoside catabolic process

primary metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fucose metabolic process

small molecule metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fucose metabolic process

organic substance metabolic process [inference]

carbohydrate metabolic process [inference]

monosaccharide metabolic process [inference]

hexose metabolic process [inference]

fucose metabolic process

carbohydrate derivative metabolic process [inference]

carbohydrate derivative catabolic process [inference]

glycosyl compound catabolic process [inference]

glycoside catabolic process

glycosyl compound metabolic process [inference]

glycoside metabolic process [inference]

glycoside catabolic process

glycosyl compound catabolic process [inference]

glycoside catabolic process

organic substance catabolic process [inference]

carbohydrate derivative catabolic process [inference]

glycosyl compound catabolic process [inference]

glycoside catabolic process

biological process involved in interspecies interaction between organisms [inference]

response to other organism [inference]

response to bacterium

response to stimulus [inference]

response to external stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium

response to biotic stimulus [inference]

response to external biotic stimulus [inference]

response to other organism [inference]

response to bacterium

biological regulation [inference]

regulation of biological process [inference]

regulation of biological process involved in symbiotic interaction [inference]

modulation by symbiont of entry into host [inference]

regulation of entry of bacterium into host cell

Displaying **all 3** entries
GO Term	Evidence Code	PMID
extracellular space	ISO
extracellular space	IEA
lysosome	IBA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

extracellular space

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

Displaying **all 3** entries
GO Term	Evidence Code	PMID
alpha-L-fucosidase activity	ISO
alpha-L-fucosidase activity	IBA
alpha-L-fucosidase activity	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on glycosyl bonds [inference]

hydrolase activity, hydrolyzing O-glycosyl compounds [inference]

fucosidase activity [inference]

alpha-L-fucosidase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

alpha L fucosidase

Functional Category

E: Amino acid transport and metabolism
G: Carbohydrate transport and metabolism
K: Transcription
M: Cell wall/membrane/envelope biogenesis

Displaying **all 4** entries
Gene Ontology
alpha-L-fucosidase activity
fucose metabolic process
fucosidase activity
hydrolase activity

Displaying **all 3** entries
InterPro
Alpha-L-fucosidase, metazoa-type
Glycoside hydrolase superfamily
Glycoside hydrolase, family 29

Rhea

H₂O + an α-L-fucoside

L-fucose + an alcohol

Enzyme

3.2.1.51

PMID

Ortholog

Displaying entries **1 - 10** of 83 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Drosophila melanogaster	2517	FB:FBgn0285958
Homo sapiens	2519	Xenbase:XB-GENE-945131	HUMAN86836
Drosophila melanogaster	24375	FB:FBgn0285958
Xenopus tropicalis	66848	Xenbase:XB-GENE-945131
Drosophila melanogaster	71665	FB:FBgn0285958
Xenopus tropicalis	189173	Xenbase:XB-GENE-945131
Xenopus tropicalis	292485	Xenbase:XB-GENE-945131
Danio rerio	445487		DANRE11941
Pan troglodytes	463039		PANTR39222
Bos taurus	515729		BOVIN35913

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GlyCosmos is a member of the GlySpace Alliance together with GlyGen and Glycomics@ExPASy.

Acknowledgements

Supported by JST NBDC Grant Number JPMJND2204

Partly supported by NIH Common Fund Grant #1U01GM125267-01

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GlyCosmos Portal v4.2.1

Last updated: April 7, 2025