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peptidase (mitochondrial processing) alpha

Summary

Gene Symbol

Pmpca

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

66865

PubChem

66865

Alliance of Genome Resources

MGI:1918568

Annotation

Keyword

Acetylation
Direct protein sequencing
Mitochondrion inner membrane
Reference proteome
Transit peptide

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9DC61	Alpha-MPP Inactive zinc metalloprotease alpha P-55

Annotation information from UniProt.

Gene Ontology (GO)

Displaying **all 4** entries
GO Term	Evidence Code	PMID
protein processing involved in protein targeting to mitochondrion	ISS
protein processing involved in protein targeting to mitochondrion	ISO
protein processing involved in protein targeting to mitochondrion	IBA
protein processing	ISO

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing

mitochondrial protein processing [inference]

protein processing involved in protein targeting to mitochondrion

protein maturation [inference]

protein processing

mitochondrial protein processing [inference]

protein processing involved in protein targeting to mitochondrion

primary metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing

mitochondrial protein processing [inference]

protein processing involved in protein targeting to mitochondrion

protein maturation [inference]

protein processing

mitochondrial protein processing [inference]

protein processing involved in protein targeting to mitochondrion

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing

mitochondrial protein processing [inference]

protein processing involved in protein targeting to mitochondrion

protein maturation [inference]

protein processing

mitochondrial protein processing [inference]

protein processing involved in protein targeting to mitochondrion

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

proteolysis [inference]

protein processing

mitochondrial protein processing [inference]

protein processing involved in protein targeting to mitochondrion

protein maturation [inference]

protein processing

mitochondrial protein processing [inference]

protein processing involved in protein targeting to mitochondrion

Displaying entries **1 - 5** of 6 in total

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GO Term	Evidence Code	PMID
mitochondrion	ISO
mitochondrion	IBA
mitochondrion	HDA	18614015
mitochondrial inner membrane	ISS
mitochondrial inner membrane	ISO

GO Hierarchy

cellular component

cellular anatomical entity [inference]

membrane [inference]

organelle membrane [inference]

organelle inner membrane [inference]

mitochondrial inner membrane

mitochondrial membrane [inference]

mitochondrial inner membrane

membrane-enclosed lumen [inference]

organelle lumen [inference]

intracellular organelle lumen [inference]

mitochondrial matrix

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

mitochondrion

Displaying **all 4** entries
GO Term	Evidence Code	PMID
endopeptidase activity	ISO
metalloendopeptidase activity	IEA
metallopeptidase activity	ISO
metal ion binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

peptidase activity [inference]

endopeptidase activity

metalloendopeptidase activity

metallopeptidase activity

metalloendopeptidase activity

catalytic activity, acting on a protein [inference]

peptidase activity [inference]

endopeptidase activity

metalloendopeptidase activity

metallopeptidase activity

metalloendopeptidase activity

binding [inference]

ion binding [inference]

cation binding [inference]

metal ion binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Peptidase

Functional Category

K: Transcription
M: Cell wall/membrane/envelope biogenesis
O: Posttranslational modification, protein turnover, chaperones

Displaying **all 4** entries
Gene Ontology
metal ion binding
metalloendopeptidase activity
protein processing involved in protein targeting to mitochondrion
proteolysis

Displaying **all 4** entries
InterPro
Metalloenzyme, LuxS/M16 peptidase-like
Peptidase M16, C-terminal
Peptidase M16, N-terminal
Peptidase M16, zinc-binding site

Ortholog

Displaying entries **1 - 10** of 74 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	23203	Xenbase:XB-GENE-977435	HUMAN99300
Xenopus tropicalis	66865	Xenbase:XB-GENE-977435
Rattus norvegicus	296588		RATNO27231
Canis lupus familiaris	480677		CANLF19267
Danio rerio	492801		DANRE36867
Macaca mulatta	721742		MACMU12956
Bos taurus	767847		BOVIN03416
Monodelphis domestica	100020320		MONDO05706
Equus caballus	100068710		HORSE23903
Ornithorhynchus anatinus	100092395		ORNAN21029