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DEAD box helicase 18

Summary

Gene Symbol

Ddx18

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

66942

PubChem

66942

Alliance of Genome Resources

MGI:1914192

Annotation

Keyword

Chromosome
Helicase
Nucleus
RNA-binding
Reference proteome

Proteins

Displaying **all 2** entries
UniProt	Protein Name
Q8K363	DEAD box protein 18
B2RUM8

Annotation information from UniProt.

Gene Ontology (GO)

Displaying 1 entry
GO Term	Evidence Code	PMID
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	IBA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

maturation of LSU-rRNA [inference]

maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

maturation of LSU-rRNA [inference]

maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

ncRNA processing [inference]

rRNA processing [inference]

maturation of LSU-rRNA [inference]

maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

maturation of LSU-rRNA [inference]

maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

maturation of LSU-rRNA [inference]

maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

ncRNA processing [inference]

rRNA processing [inference]

maturation of LSU-rRNA [inference]

maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

maturation of LSU-rRNA [inference]

maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

maturation of LSU-rRNA [inference]

maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

ncRNA processing [inference]

rRNA processing [inference]

maturation of LSU-rRNA [inference]

maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

maturation of LSU-rRNA [inference]

maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

maturation of LSU-rRNA [inference]

maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

ncRNA processing [inference]

rRNA processing [inference]

maturation of LSU-rRNA [inference]

maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

maturation of LSU-rRNA [inference]

maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

maturation of LSU-rRNA [inference]

maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

ncRNA processing [inference]

rRNA processing [inference]

maturation of LSU-rRNA [inference]

maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

maturation of LSU-rRNA [inference]

maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

maturation of LSU-rRNA [inference]

maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

ncRNA processing [inference]

rRNA processing [inference]

maturation of LSU-rRNA [inference]

maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

maturation of LSU-rRNA [inference]

maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

maturation of LSU-rRNA [inference]

maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

ncRNA processing [inference]

rRNA processing [inference]

maturation of LSU-rRNA [inference]

maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

cellular process [inference]

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

maturation of LSU-rRNA [inference]

maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

maturation of LSU-rRNA [inference]

maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

ncRNA processing [inference]

rRNA processing [inference]

maturation of LSU-rRNA [inference]

maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

maturation of LSU-rRNA [inference]

maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

maturation of LSU-rRNA [inference]

maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

ncRNA processing [inference]

rRNA processing [inference]

maturation of LSU-rRNA [inference]

maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

RNA metabolic process [inference]

RNA processing [inference]

ncRNA processing [inference]

rRNA processing [inference]

maturation of LSU-rRNA [inference]

maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

ncRNA metabolic process [inference]

rRNA metabolic process [inference]

rRNA processing [inference]

maturation of LSU-rRNA [inference]

maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

ncRNA processing [inference]

rRNA processing [inference]

maturation of LSU-rRNA [inference]

maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)

Displaying **all 2** entries
GO Term	Evidence Code	PMID
chromosome	ISO ISS
nucleolus	IBA ISO ISS

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

intracellular organelle [inference]

intracellular non-membrane-bounded organelle [inference]

Displaying **all 4** entries
GO Term	Evidence Code	PMID
ATP hydrolysis activity	IEA
RNA helicase activity	IEA
ATP binding	IEA
RNA binding	IEA

GO Hierarchy

molecular function

catalytic activity [inference]

hydrolase activity [inference]

hydrolase activity, acting on acid anhydrides [inference]

hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides [inference]

pyrophosphatase activity [inference]

ribonucleoside triphosphate phosphatase activity [inference]

ATP hydrolysis activity

catalytic activity, acting on a nucleic acid [inference]

helicase activity [inference]

RNA helicase activity

catalytic activity, acting on RNA [inference]

RNA helicase activity

binding [inference]

small molecule binding [inference]

heterocyclic compound binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ion binding [inference]

anion binding [inference]

purine ribonucleoside triphosphate binding [inference]

ATP binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

RNA binding

nucleoside phosphate binding [inference]

nucleotide binding [inference]

purine nucleotide binding [inference]

adenyl nucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

purine ribonucleoside triphosphate binding [inference]

ATP binding

carbohydrate derivative binding [inference]

ribonucleotide binding [inference]

purine ribonucleotide binding [inference]

adenyl ribonucleotide binding [inference]

ATP binding

ATP-dependent activity [inference]

helicase activity [inference]

RNA helicase activity

ATP-dependent activity, acting on RNA [inference]

RNA helicase activity

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Rodentia

Group Name

ATP-dependent RNA helicase DDX18

Functional Category

J: Translation, ribosomal structure and biogenesis
K: Transcription
L: Replication, recombination and repair
V: Defense mechanisms

Displaying **all 4** entries
Gene Ontology
ATP binding
hydrolase activity
maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
nucleotide binding

Displaying **all 6** entries
InterPro
ATP-dependent RNA helicase DEAD-box, conserved site
DDX18/Has1, DEAD-box helicase domain
DEAD/DEAH box helicase domain
Helicase superfamily 1/2, ATP-binding domain
Helicase, C-terminal domain-like
P-loop containing nucleoside triphosphate hydrolase

Ortholog

Displaying entries **1 - 10** of **134** in total

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Last »
Species	Gene ID	OrthoDB	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	8886		HGNC:2741	HUMAN64478
Drosophila melanogaster	42595		FB:FBgn0266581
Caenorhabditis elegans	172954		WB:WBGene00015232
Rattus norvegicus	308490	10116_1:004098	RGD:1549712
Danio rerio	321127		ZFIN:ZDB-GENE-030131-9685	DANRE44201
Pan troglodytes	459566			PANTR28517
Canis lupus familiaris	476120			CANLF06361
Xenopus tropicalis	549530		Xenbase:XB-GENE-6085268
Macaca mulatta	693278			MACMU06436
Saccharomyces cerevisiae S288C	855335		SGD:S000004903

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Last updated: December 9, 2024