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Guidelines

MIRAGE

F-box protein 5

Summary

Gene Symbol

Fbxo5

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

67141

PubChem

67141

Alliance of Genome Resources

MGI:1914391

Annotation

Keyword

Cytoskeleton
Mitosis
Nucleus
Phosphoprotein
Reference proteome
Ubl conjugation
Ubl conjugation pathway
Zinc-finger

Proteins

Displaying 1 entry
UniProt	Protein Name
Q7TSG3	Early mitotic inhibitor 1

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **31 - 35** of 40 in total

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GO Term	Evidence Code	PMID
negative regulation of ubiquitin-protein transferase activity	ISO	17190794
positive regulation of meiosis I	ISO	17190794
positive regulation of biomineral tissue development	ISS
positive regulation of biomineral tissue development	ISO
negative regulation of ubiquitin protein ligase activity	ISS

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

primary metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

macromolecule modification [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

organonitrogen compound metabolic process [inference]

protein metabolic process [inference]

protein modification process [inference]

post-translational protein modification [inference]

protein modification by small protein conjugation or removal [inference]

protein modification by small protein conjugation [inference]

protein ubiquitination

cellular process [inference]

microtubule-based process [inference]

microtubule cytoskeleton organization [inference]

spindle organization [inference]

meiotic spindle organization [inference]

meiotic spindle assembly [inference]

spindle assembly involved in female meiosis [inference]

spindle assembly involved in female meiosis I

spindle assembly

meiotic spindle assembly [inference]

spindle assembly involved in female meiosis [inference]

spindle assembly involved in female meiosis I

microtubule polymerization or depolymerization [inference]

microtubule polymerization

cell cycle process [inference]

spindle organization [inference]

meiotic spindle organization [inference]

meiotic spindle assembly [inference]

spindle assembly involved in female meiosis [inference]

spindle assembly involved in female meiosis I

spindle assembly

meiotic spindle assembly [inference]

spindle assembly involved in female meiosis [inference]

spindle assembly involved in female meiosis I

meiotic cell cycle process [inference]

meiotic spindle organization [inference]

meiotic spindle assembly [inference]

spindle assembly involved in female meiosis [inference]

spindle assembly involved in female meiosis I

cellular process involved in reproduction in multicellular organism [inference]

oocyte maturation

spindle assembly involved in female meiosis [inference]

spindle assembly involved in female meiosis I

cellular developmental process [inference]

cell maturation [inference]

oocyte maturation

cell division

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

cytoskeleton organization [inference]

microtubule cytoskeleton organization [inference]

spindle organization [inference]

meiotic spindle organization [inference]

meiotic spindle assembly [inference]

spindle assembly involved in female meiosis [inference]

spindle assembly involved in female meiosis I

spindle assembly

meiotic spindle assembly [inference]

spindle assembly involved in female meiosis [inference]

spindle assembly involved in female meiosis I

microtubule polymerization or depolymerization [inference]

microtubule polymerization

vesicle organization

organelle assembly [inference]

non-membrane-bounded organelle assembly [inference]

spindle assembly

meiotic spindle assembly [inference]

spindle assembly involved in female meiosis [inference]

spindle assembly involved in female meiosis I

cellular component assembly [inference]

protein-containing complex assembly [inference]

protein polymerization [inference]

microtubule polymerization

organelle assembly [inference]

non-membrane-bounded organelle assembly [inference]

spindle assembly

meiotic spindle assembly [inference]

spindle assembly involved in female meiosis [inference]

spindle assembly involved in female meiosis I

protein-containing complex organization [inference]

protein-containing complex assembly [inference]

protein polymerization [inference]

microtubule polymerization

supramolecular fiber organization [inference]

microtubule polymerization

reproductive process [inference]

developmental process involved in reproduction [inference]

oocyte maturation

cellular process involved in reproduction in multicellular organism [inference]

oocyte maturation

spindle assembly involved in female meiosis [inference]

spindle assembly involved in female meiosis I

meiotic cell cycle process [inference]

meiotic spindle organization [inference]

meiotic spindle assembly [inference]

spindle assembly involved in female meiosis [inference]

spindle assembly involved in female meiosis I

developmental process [inference]

developmental process involved in reproduction [inference]

oocyte maturation

developmental maturation [inference]

anatomical structure maturation [inference]

cell maturation [inference]

oocyte maturation

cellular developmental process [inference]

cell maturation [inference]

oocyte maturation

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

cellular response to stimulus [inference]

cellular response to stress [inference]

cellular response to DNA damage stimulus

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of post-translational protein modification [inference]

negative regulation of protein modification by small protein conjugation or removal [inference]

negative regulation of protein ubiquitination [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

negative regulation of cellular metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

negative regulation of cellular senescence

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of post-translational protein modification [inference]

negative regulation of protein modification by small protein conjugation or removal [inference]

negative regulation of protein ubiquitination [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

regulation of DNA metabolic process [inference]

regulation of DNA replication

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

regulation of DNA-templated DNA replication [inference]

regulation of DNA endoreduplication [inference]

negative regulation of DNA endoreduplication

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

negative regulation of cellular metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

negative regulation of cellular senescence

regulation of cellular senescence [inference]

negative regulation of cellular senescence

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

regulation of DNA metabolic process [inference]

regulation of DNA replication

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

regulation of DNA-templated DNA replication [inference]

regulation of DNA endoreduplication [inference]

negative regulation of DNA endoreduplication

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of post-translational protein modification [inference]

negative regulation of protein modification by small protein conjugation or removal [inference]

negative regulation of protein ubiquitination [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

negative regulation of protein modification process [inference]

negative regulation of post-translational protein modification [inference]

negative regulation of protein modification by small protein conjugation or removal [inference]

negative regulation of protein ubiquitination [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

regulation of post-translational protein modification [inference]

negative regulation of post-translational protein modification [inference]

negative regulation of protein modification by small protein conjugation or removal [inference]

negative regulation of protein ubiquitination [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

regulation of protein modification by small protein conjugation or removal [inference]

regulation of protein ubiquitination [inference]

negative regulation of protein ubiquitination [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

negative regulation of protein modification by small protein conjugation or removal [inference]

negative regulation of protein ubiquitination [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of post-translational protein modification [inference]

negative regulation of protein modification by small protein conjugation or removal [inference]

negative regulation of protein ubiquitination [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

regulation of macromolecule metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of post-translational protein modification [inference]

negative regulation of protein modification by small protein conjugation or removal [inference]

negative regulation of protein ubiquitination [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

regulation of DNA metabolic process [inference]

regulation of DNA replication

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

regulation of DNA-templated DNA replication [inference]

regulation of DNA endoreduplication [inference]

negative regulation of DNA endoreduplication

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

negative regulation of protein modification process [inference]

negative regulation of post-translational protein modification [inference]

negative regulation of protein modification by small protein conjugation or removal [inference]

negative regulation of protein ubiquitination [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

regulation of post-translational protein modification [inference]

negative regulation of post-translational protein modification [inference]

negative regulation of protein modification by small protein conjugation or removal [inference]

negative regulation of protein ubiquitination [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

regulation of protein modification by small protein conjugation or removal [inference]

regulation of protein ubiquitination [inference]

negative regulation of protein ubiquitination [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

negative regulation of protein modification by small protein conjugation or removal [inference]

negative regulation of protein ubiquitination [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of post-translational protein modification [inference]

negative regulation of protein modification by small protein conjugation or removal [inference]

negative regulation of protein ubiquitination [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

regulation of DNA metabolic process [inference]

regulation of DNA replication

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

regulation of DNA-templated DNA replication [inference]

regulation of DNA endoreduplication [inference]

negative regulation of DNA endoreduplication

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

regulation of protein metabolic process [inference]

regulation of protein modification process [inference]

negative regulation of protein modification process [inference]

negative regulation of post-translational protein modification [inference]

negative regulation of protein modification by small protein conjugation or removal [inference]

negative regulation of protein ubiquitination [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

regulation of post-translational protein modification [inference]

negative regulation of post-translational protein modification [inference]

negative regulation of protein modification by small protein conjugation or removal [inference]

negative regulation of protein ubiquitination [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

regulation of protein modification by small protein conjugation or removal [inference]

regulation of protein ubiquitination [inference]

negative regulation of protein ubiquitination [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

negative regulation of protein modification by small protein conjugation or removal [inference]

negative regulation of protein ubiquitination [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of post-translational protein modification [inference]

negative regulation of protein modification by small protein conjugation or removal [inference]

negative regulation of protein ubiquitination [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

regulation of locomotion [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of mesenchymal stem cell migration

regulation of cell motility [inference]

regulation of cell migration [inference]

positive regulation of cell migration [inference]

positive regulation of mesenchymal stem cell migration

regulation of mesenchymal stem cell migration [inference]

positive regulation of mesenchymal stem cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of mesenchymal stem cell migration

positive regulation of biological process [inference]

positive regulation of locomotion [inference]

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of mesenchymal stem cell migration

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cell differentiation [inference]

positive regulation of osteoblast differentiation

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic nuclear division [inference]

positive regulation of meiosis I

positive regulation of cell cycle process [inference]

positive regulation of meiotic nuclear division [inference]

positive regulation of meiosis I

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cell cycle G2/M phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of nuclear division [inference]

positive regulation of meiotic nuclear division [inference]

positive regulation of meiosis I

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of mesenchymal stem cell migration

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of osteoblast differentiation

positive regulation of biomineral tissue development

positive regulation of reproductive process [inference]

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic nuclear division [inference]

positive regulation of meiosis I

negative regulation of biological process [inference]

negative regulation of metabolic process [inference]

negative regulation of macromolecule metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of post-translational protein modification [inference]

negative regulation of protein modification by small protein conjugation or removal [inference]

negative regulation of protein ubiquitination [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

negative regulation of cellular metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

negative regulation of cellular senescence

negative regulation of nitrogen compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

negative regulation of protein metabolic process [inference]

negative regulation of protein modification process [inference]

negative regulation of post-translational protein modification [inference]

negative regulation of protein modification by small protein conjugation or removal [inference]

negative regulation of protein ubiquitination [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

negative regulation of cellular senescence

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of chromosome segregation [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of chromosome separation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of cell cycle phase transition [inference]

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of metaphase/anaphase transition of cell cycle [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of mitotic cell cycle [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of meiotic cell cycle [inference]

negative regulation of meiotic nuclear division

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of nuclear division [inference]

negative regulation of meiotic nuclear division

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of chromosome organization [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of reproductive process [inference]

negative regulation of meiotic cell cycle [inference]

negative regulation of meiotic nuclear division

regulation of developmental process [inference]

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of osteoblast differentiation

regulation of osteoblast differentiation [inference]

positive regulation of osteoblast differentiation

positive regulation of developmental process [inference]

positive regulation of cell differentiation [inference]

positive regulation of osteoblast differentiation

positive regulation of biomineral tissue development

regulation of multicellular organismal development [inference]

regulation of biomineral tissue development [inference]

positive regulation of biomineral tissue development

regulation of cellular process [inference]

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

regulation of DNA metabolic process [inference]

regulation of DNA replication

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

regulation of DNA-templated DNA replication [inference]

regulation of DNA endoreduplication [inference]

negative regulation of DNA endoreduplication

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

negative regulation of cellular metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

negative regulation of cellular senescence

regulation of cellular senescence [inference]

negative regulation of cellular senescence

regulation of cell population proliferation [inference]

positive regulation of cell population proliferation

regulation of cell differentiation [inference]

positive regulation of cell differentiation [inference]

positive regulation of osteoblast differentiation

regulation of osteoblast differentiation [inference]

positive regulation of osteoblast differentiation

positive regulation of cellular process [inference]

positive regulation of cell population proliferation

positive regulation of cell differentiation [inference]

positive regulation of osteoblast differentiation

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic nuclear division [inference]

positive regulation of meiosis I

positive regulation of cell cycle process [inference]

positive regulation of meiotic nuclear division [inference]

positive regulation of meiosis I

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cell cycle G2/M phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of nuclear division [inference]

positive regulation of meiotic nuclear division [inference]

positive regulation of meiosis I

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of mesenchymal stem cell migration

negative regulation of cellular process [inference]

negative regulation of cellular metabolic process [inference]

negative regulation of nucleobase-containing compound metabolic process [inference]

negative regulation of DNA metabolic process [inference]

negative regulation of DNA replication [inference]

negative regulation of DNA-templated DNA replication [inference]

negative regulation of DNA endoreduplication

negative regulation of cellular senescence

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of chromosome segregation [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of chromosome separation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of cell cycle phase transition [inference]

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of metaphase/anaphase transition of cell cycle [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of mitotic cell cycle [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of meiotic cell cycle [inference]

negative regulation of meiotic nuclear division

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of nuclear division [inference]

negative regulation of meiotic nuclear division

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of chromosome organization [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition

regulation of cellular component organization [inference]

regulation of organelle organization [inference]

positive regulation of organelle organization [inference]

positive regulation of nuclear division [inference]

positive regulation of meiotic nuclear division [inference]

positive regulation of meiosis I

negative regulation of organelle organization [inference]

negative regulation of nuclear division [inference]

negative regulation of meiotic nuclear division

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of chromosome organization [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition

regulation of chromosome organization [inference]

regulation of sister chromatid segregation [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition

regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition

regulation of metaphase/anaphase transition of cell cycle [inference]

regulation of mitotic metaphase/anaphase transition [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of metaphase/anaphase transition of cell cycle [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of chromosome organization [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition

regulation of nuclear division [inference]

regulation of mitotic nuclear division

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition

regulation of meiotic nuclear division

negative regulation of meiotic nuclear division

positive regulation of meiotic nuclear division [inference]

positive regulation of meiosis I

regulation of meiosis I [inference]

positive regulation of meiosis I

negative regulation of nuclear division [inference]

negative regulation of meiotic nuclear division

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition

positive regulation of nuclear division [inference]

positive regulation of meiotic nuclear division [inference]

positive regulation of meiosis I

negative regulation of cellular component organization [inference]

negative regulation of organelle organization [inference]

negative regulation of nuclear division [inference]

negative regulation of meiotic nuclear division

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of chromosome organization [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition

positive regulation of cellular component organization [inference]

positive regulation of organelle organization [inference]

positive regulation of nuclear division [inference]

positive regulation of meiotic nuclear division [inference]

positive regulation of meiosis I

regulation of cell cycle [inference]

regulation of mitotic cell cycle

regulation of mitotic nuclear division

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of mitotic cell cycle [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

regulation of mitotic cell cycle phase transition [inference]

regulation of G2/M transition of mitotic cell cycle [inference]

positive regulation of G2/M transition of mitotic cell cycle

regulation of mitotic metaphase/anaphase transition [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

regulation of cell cycle process [inference]

regulation of mitotic nuclear division

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of cell cycle process [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of chromosome segregation [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of chromosome separation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of cell cycle phase transition [inference]

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of metaphase/anaphase transition of cell cycle [inference]

negative regulation of mitotic metaphase/anaphase transition

regulation of DNA endoreduplication [inference]

negative regulation of DNA endoreduplication

regulation of meiotic nuclear division

negative regulation of meiotic nuclear division

positive regulation of meiotic nuclear division [inference]

positive regulation of meiosis I

regulation of meiosis I [inference]

positive regulation of meiosis I

regulation of chromosome segregation [inference]

regulation of sister chromatid segregation [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition

regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition

regulation of metaphase/anaphase transition of cell cycle [inference]

regulation of mitotic metaphase/anaphase transition [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of metaphase/anaphase transition of cell cycle [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of chromosome segregation [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of chromosome separation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition

regulation of chromosome separation [inference]

regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of chromosome separation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition

positive regulation of cell cycle process [inference]

positive regulation of meiotic nuclear division [inference]

positive regulation of meiosis I

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cell cycle G2/M phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

regulation of cell cycle phase transition [inference]

negative regulation of cell cycle phase transition [inference]

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of metaphase/anaphase transition of cell cycle [inference]

negative regulation of mitotic metaphase/anaphase transition

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cell cycle G2/M phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

regulation of mitotic cell cycle phase transition [inference]

regulation of G2/M transition of mitotic cell cycle [inference]

positive regulation of G2/M transition of mitotic cell cycle

regulation of mitotic metaphase/anaphase transition [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

regulation of metaphase/anaphase transition of cell cycle [inference]

regulation of mitotic metaphase/anaphase transition [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of metaphase/anaphase transition of cell cycle [inference]

negative regulation of mitotic metaphase/anaphase transition

regulation of cell cycle G2/M phase transition [inference]

regulation of G2/M transition of mitotic cell cycle [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cell cycle G2/M phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

negative regulation of cell cycle [inference]

negative regulation of cell cycle process [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of chromosome segregation [inference]

negative regulation of sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid segregation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of chromosome separation [inference]

negative regulation of mitotic sister chromatid separation [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of cell cycle phase transition [inference]

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of metaphase/anaphase transition of cell cycle [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of mitotic cell cycle [inference]

negative regulation of mitotic nuclear division [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of mitotic cell cycle phase transition [inference]

negative regulation of mitotic metaphase/anaphase transition

negative regulation of meiotic cell cycle [inference]

negative regulation of meiotic nuclear division

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic nuclear division [inference]

positive regulation of meiosis I

positive regulation of cell cycle process [inference]

positive regulation of meiotic nuclear division [inference]

positive regulation of meiosis I

positive regulation of cell cycle phase transition [inference]

positive regulation of mitotic cell cycle phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

positive regulation of cell cycle G2/M phase transition [inference]

positive regulation of G2/M transition of mitotic cell cycle

regulation of meiotic cell cycle [inference]

regulation of meiotic nuclear division

negative regulation of meiotic nuclear division

positive regulation of meiotic nuclear division [inference]

positive regulation of meiosis I

regulation of meiosis I [inference]

positive regulation of meiosis I

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic nuclear division [inference]

positive regulation of meiosis I

negative regulation of meiotic cell cycle [inference]

negative regulation of meiotic nuclear division

regulation of cell motility [inference]

regulation of cell migration [inference]

positive regulation of cell migration [inference]

positive regulation of mesenchymal stem cell migration

regulation of mesenchymal stem cell migration [inference]

positive regulation of mesenchymal stem cell migration

positive regulation of cell motility [inference]

positive regulation of cell migration [inference]

positive regulation of mesenchymal stem cell migration

regulation of multicellular organismal process [inference]

regulation of multicellular organismal development [inference]

regulation of biomineral tissue development [inference]

positive regulation of biomineral tissue development

regulation of reproductive process [inference]

regulation of meiotic cell cycle [inference]

regulation of meiotic nuclear division

negative regulation of meiotic nuclear division

positive regulation of meiotic nuclear division [inference]

positive regulation of meiosis I

regulation of meiosis I [inference]

positive regulation of meiosis I

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic nuclear division [inference]

positive regulation of meiosis I

negative regulation of meiotic cell cycle [inference]

negative regulation of meiotic nuclear division

negative regulation of reproductive process [inference]

negative regulation of meiotic cell cycle [inference]

negative regulation of meiotic nuclear division

positive regulation of reproductive process [inference]

positive regulation of meiotic cell cycle [inference]

positive regulation of meiotic nuclear division [inference]

positive regulation of meiosis I

regulation of molecular function [inference]

negative regulation of molecular function [inference]

negative regulation of catalytic activity [inference]

negative regulation of transferase activity [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

regulation of catalytic activity [inference]

negative regulation of catalytic activity [inference]

negative regulation of transferase activity [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

regulation of transferase activity [inference]

negative regulation of transferase activity [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

regulation of ubiquitin-protein transferase activity [inference]

negative regulation of ubiquitin-protein transferase activity

negative regulation of ubiquitin protein ligase activity

regulation of ubiquitin protein ligase activity [inference]

negative regulation of ubiquitin protein ligase activity

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
nucleus	ISS
nucleus	ISO
nucleus	IBA
nucleoplasm	ISO
nucleoplasm	IEA

GO Hierarchy

cellular component

cellular anatomical entity [inference]

organelle [inference]

membrane-bounded organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

non-membrane-bounded organelle [inference]

intracellular non-membrane-bounded organelle [inference]

meiotic spindle

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular non-membrane-bounded organelle [inference]

meiotic spindle

Displaying entries **1 - 5** of 10 in total

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GO Term	Evidence Code	PMID
protein binding	IPI	15526037
zinc ion binding	IEA
anaphase-promoting complex binding	ISS
anaphase-promoting complex binding	ISO
protein kinase binding	ISO

GO Hierarchy

molecular function

binding [inference]

protein binding

enzyme binding [inference]

kinase binding [inference]

protein kinase binding

ion binding [inference]

cation binding [inference]

metal ion binding

transition metal ion binding [inference]

zinc ion binding

protein-containing complex binding [inference]

anaphase-promoting complex binding

molecular function regulator activity [inference]

enzyme regulator activity [inference]

enzyme inhibitor activity [inference]

ubiquitin-protein transferase inhibitor activity [inference]

ubiquitin ligase inhibitor activity

ubiquitin-protein transferase regulator activity [inference]

ubiquitin-protein transferase inhibitor activity [inference]

ubiquitin ligase inhibitor activity

molecular function inhibitor activity

enzyme inhibitor activity [inference]

ubiquitin-protein transferase inhibitor activity [inference]

ubiquitin ligase inhibitor activity

Gene Ontology information from NCBI Gene and UniProt.

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Partly supported by NIH Common Fund Grant #1U01GM125267-01

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Last updated: April 6, 2026