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BRCA2 DNA repair associated

Summary

Gene Symbol

BRCA2

Organism

Homo sapiens (human)

External Links

NCBI Gene

675

PubChem

675

Alliance of Genome Resources

HGNC:1101

JoGo

BRCA2

TogoVar

BRCA2

Annotation

Keyword

3D-structure
Cell cycle
Cytoskeleton
DNA recombination
DNA repair
DNA-binding
Disease variant
Fanconi anemia
Nucleus
Phosphoprotein
Proteomics identification
Reference proteome
Repeat
Tumor suppressor
Ubl conjugation

Proteins

Displaying **all 3** entries
UniProt	Protein Name
A0A8V8TPZ2
A0A7P0T9D7
P51587	Fanconi anemia group D1 protein

Annotation information from UniProt.

Gene Ontology (GO)

Displaying entries **1 - 5** of 32 in total

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GO Term	Evidence Code	PMID
telomere maintenance via recombination	IEA
double-strand break repair via homologous recombination	IDA	20729832 28398198
double-strand break repair via homologous recombination	IMP	21719596
double-strand break repair via homologous recombination	IBA
oocyte maturation	IEA

GO Hierarchy

biological process

metabolic process [inference]

nitrogen compound metabolic process [inference]

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

telomere maintenance [inference]

telomere maintenance via recombination

DNA repair [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination

nucleotide-excision repair

double-strand break repair

double-strand break repair via homologous recombination

DNA recombination [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination

mitotic recombination [inference]

telomere maintenance via recombination

DNA-templated DNA replication maintenance of fidelity [inference]

replication fork processing [inference]

mitotic recombination-dependent replication fork processing

cell cycle DNA replication maintenance of fidelity [inference]

mitotic DNA replication maintenance of fidelity [inference]

mitotic recombination-dependent replication fork processing

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

telomere maintenance [inference]

telomere maintenance via recombination

DNA repair [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination

nucleotide-excision repair

double-strand break repair

double-strand break repair via homologous recombination

DNA recombination [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination

mitotic recombination [inference]

telomere maintenance via recombination

DNA-templated DNA replication maintenance of fidelity [inference]

replication fork processing [inference]

mitotic recombination-dependent replication fork processing

cell cycle DNA replication maintenance of fidelity [inference]

mitotic DNA replication maintenance of fidelity [inference]

mitotic recombination-dependent replication fork processing

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

telomere maintenance [inference]

telomere maintenance via recombination

DNA repair [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination

nucleotide-excision repair

double-strand break repair

double-strand break repair via homologous recombination

DNA recombination [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination

mitotic recombination [inference]

telomere maintenance via recombination

DNA-templated DNA replication maintenance of fidelity [inference]

replication fork processing [inference]

mitotic recombination-dependent replication fork processing

cell cycle DNA replication maintenance of fidelity [inference]

mitotic DNA replication maintenance of fidelity [inference]

mitotic recombination-dependent replication fork processing

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

telomere maintenance [inference]

telomere maintenance via recombination

DNA repair [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination

nucleotide-excision repair

double-strand break repair

double-strand break repair via homologous recombination

DNA recombination [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination

mitotic recombination [inference]

telomere maintenance via recombination

DNA-templated DNA replication maintenance of fidelity [inference]

replication fork processing [inference]

mitotic recombination-dependent replication fork processing

cell cycle DNA replication maintenance of fidelity [inference]

mitotic DNA replication maintenance of fidelity [inference]

mitotic recombination-dependent replication fork processing

cellular senescence

primary metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

telomere maintenance [inference]

telomere maintenance via recombination

DNA repair [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination

nucleotide-excision repair

double-strand break repair

double-strand break repair via homologous recombination

DNA recombination [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination

mitotic recombination [inference]

telomere maintenance via recombination

DNA-templated DNA replication maintenance of fidelity [inference]

replication fork processing [inference]

mitotic recombination-dependent replication fork processing

cell cycle DNA replication maintenance of fidelity [inference]

mitotic DNA replication maintenance of fidelity [inference]

mitotic recombination-dependent replication fork processing

organic substance metabolic process [inference]

macromolecule metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

telomere maintenance [inference]

telomere maintenance via recombination

DNA repair [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination

nucleotide-excision repair

double-strand break repair

double-strand break repair via homologous recombination

DNA recombination [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination

mitotic recombination [inference]

telomere maintenance via recombination

DNA-templated DNA replication maintenance of fidelity [inference]

replication fork processing [inference]

mitotic recombination-dependent replication fork processing

cell cycle DNA replication maintenance of fidelity [inference]

mitotic DNA replication maintenance of fidelity [inference]

mitotic recombination-dependent replication fork processing

organic cyclic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

telomere maintenance [inference]

telomere maintenance via recombination

DNA repair [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination

nucleotide-excision repair

double-strand break repair

double-strand break repair via homologous recombination

DNA recombination [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination

mitotic recombination [inference]

telomere maintenance via recombination

DNA-templated DNA replication maintenance of fidelity [inference]

replication fork processing [inference]

mitotic recombination-dependent replication fork processing

cell cycle DNA replication maintenance of fidelity [inference]

mitotic DNA replication maintenance of fidelity [inference]

mitotic recombination-dependent replication fork processing

cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

signal transduction in response to DNA damage [inference]

DNA damage response, signal transduction by p53 class mediator [inference]

DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator

DNA damage response, signal transduction resulting in transcription [inference]

DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator

signal transduction by p53 class mediator [inference]

DNA damage response, signal transduction by p53 class mediator [inference]

DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator

intrinsic apoptotic signaling pathway by p53 class mediator [inference]

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

intrinsic apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway in response to DNA damage [inference]

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

intrinsic apoptotic signaling pathway by p53 class mediator [inference]

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway in response to DNA damage [inference]

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

intrinsic apoptotic signaling pathway by p53 class mediator [inference]

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

cell population proliferation [inference]

inner cell mass cell proliferation

stem cell proliferation [inference]

hematopoietic stem cell proliferation

cell cycle process [inference]

centrosome duplication

cell cycle DNA replication maintenance of fidelity [inference]

mitotic DNA replication maintenance of fidelity [inference]

mitotic recombination-dependent replication fork processing

meiotic cell cycle process [inference]

meiosis I cell cycle process [inference]

meiosis I [inference]

male meiosis I

meiotic nuclear division [inference]

meiosis I [inference]

male meiosis I

male meiotic nuclear division [inference]

male meiosis I

mitotic cell cycle process [inference]

mitotic DNA replication maintenance of fidelity [inference]

mitotic recombination-dependent replication fork processing

cellular process involved in reproduction in multicellular organism [inference]

oocyte maturation

male meiotic nuclear division [inference]

male meiosis I

cellular metabolic process [inference]

cellular aromatic compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

telomere maintenance [inference]

telomere maintenance via recombination

DNA repair [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination

nucleotide-excision repair

double-strand break repair

double-strand break repair via homologous recombination

DNA recombination [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination

mitotic recombination [inference]

telomere maintenance via recombination

DNA-templated DNA replication maintenance of fidelity [inference]

replication fork processing [inference]

mitotic recombination-dependent replication fork processing

cell cycle DNA replication maintenance of fidelity [inference]

mitotic DNA replication maintenance of fidelity [inference]

mitotic recombination-dependent replication fork processing

cellular nitrogen compound metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

telomere maintenance [inference]

telomere maintenance via recombination

DNA repair [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination

nucleotide-excision repair

double-strand break repair

double-strand break repair via homologous recombination

DNA recombination [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination

mitotic recombination [inference]

telomere maintenance via recombination

DNA-templated DNA replication maintenance of fidelity [inference]

replication fork processing [inference]

mitotic recombination-dependent replication fork processing

cell cycle DNA replication maintenance of fidelity [inference]

mitotic DNA replication maintenance of fidelity [inference]

mitotic recombination-dependent replication fork processing

heterocycle metabolic process [inference]

nucleobase-containing compound metabolic process [inference]

nucleic acid metabolic process [inference]

DNA metabolic process [inference]

telomere maintenance [inference]

telomere maintenance via recombination

DNA repair [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination

nucleotide-excision repair

double-strand break repair

double-strand break repair via homologous recombination

DNA recombination [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination

mitotic recombination [inference]

telomere maintenance via recombination

DNA-templated DNA replication maintenance of fidelity [inference]

replication fork processing [inference]

mitotic recombination-dependent replication fork processing

cell cycle DNA replication maintenance of fidelity [inference]

mitotic DNA replication maintenance of fidelity [inference]

mitotic recombination-dependent replication fork processing

cellular senescence

cellular developmental process [inference]

cell maturation [inference]

oocyte maturation

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to chromosome [inference]

protein localization to chromosome, telomeric region [inference]

establishment of protein localization to telomere

establishment of protein localization to chromosome [inference]

establishment of protein localization to telomere

establishment of protein localization to organelle [inference]

establishment of protein localization to chromosome [inference]

establishment of protein localization to telomere

establishment of protein localization [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to chromosome [inference]

establishment of protein localization to telomere

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination

nucleotide-excision repair

double-strand break repair

double-strand break repair via homologous recombination

intrinsic apoptotic signaling pathway in response to DNA damage [inference]

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

signal transduction in response to DNA damage [inference]

DNA damage response, signal transduction by p53 class mediator [inference]

DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator

DNA damage response, signal transduction resulting in transcription [inference]

DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to ionizing radiation

cellular component organization or biogenesis [inference]

cellular component organization [inference]

organelle organization [inference]

organelle fission [inference]

nuclear division [inference]

meiotic nuclear division [inference]

meiosis I [inference]

male meiosis I

male meiotic nuclear division [inference]

male meiosis I

chromosome organization [inference]

telomere organization [inference]

telomere maintenance [inference]

telomere maintenance via recombination

protein-containing complex organization [inference]

protein-DNA complex organization [inference]

chromatin organization [inference]

chromatin remodeling

reproductive process [inference]

developmental process involved in reproduction [inference]

reproductive structure development [inference]

gonad development [inference]

female gonad development

cellular process involved in reproduction in multicellular organism [inference]

oocyte maturation

male meiotic nuclear division [inference]

male meiosis I

multicellular organismal reproductive process [inference]

gamete generation [inference]

male gamete generation [inference]

spermatogenesis

meiotic cell cycle process [inference]

meiosis I cell cycle process [inference]

meiosis I [inference]

male meiosis I

meiotic nuclear division [inference]

meiosis I [inference]

male meiosis I

male meiotic nuclear division [inference]

male meiosis I

developmental process [inference]

developmental process involved in reproduction [inference]

reproductive structure development [inference]

gonad development [inference]

female gonad development

developmental maturation [inference]

anatomical structure maturation [inference]

cell maturation [inference]

oocyte maturation

anatomical structure development [inference]

animal organ development [inference]

brain development

gonad development [inference]

female gonad development

reproductive structure development [inference]

gonad development [inference]

female gonad development

cellular developmental process [inference]

cell maturation [inference]

oocyte maturation

response to stimulus [inference]

response to stress [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination

nucleotide-excision repair

double-strand break repair

double-strand break repair via homologous recombination

intrinsic apoptotic signaling pathway in response to DNA damage [inference]

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

signal transduction in response to DNA damage [inference]

DNA damage response, signal transduction by p53 class mediator [inference]

DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator

DNA damage response, signal transduction resulting in transcription [inference]

DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator

response to abiotic stimulus [inference]

response to radiation [inference]

response to light stimulus [inference]

response to UV [inference]

response to UV-C

response to ionizing radiation [inference]

cellular response to radiation [inference]

cellular response to ionizing radiation

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to ionizing radiation

cellular response to stimulus [inference]

cellular response to stress [inference]

DNA damage response [inference]

DNA repair [inference]

recombinational repair [inference]

double-strand break repair via homologous recombination

nucleotide-excision repair

double-strand break repair

double-strand break repair via homologous recombination

intrinsic apoptotic signaling pathway in response to DNA damage [inference]

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

signal transduction in response to DNA damage [inference]

DNA damage response, signal transduction by p53 class mediator [inference]

DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator

DNA damage response, signal transduction resulting in transcription [inference]

DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator

cellular response to environmental stimulus [inference]

cellular response to abiotic stimulus [inference]

cellular response to radiation [inference]

cellular response to ionizing radiation

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to chromosome [inference]

protein localization to chromosome, telomeric region [inference]

establishment of protein localization to telomere

establishment of protein localization to chromosome [inference]

establishment of protein localization to telomere

establishment of protein localization to organelle [inference]

establishment of protein localization to chromosome [inference]

establishment of protein localization to telomere

establishment of protein localization [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to chromosome [inference]

establishment of protein localization to telomere

establishment of localization [inference]

establishment of protein localization [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to chromosome [inference]

establishment of protein localization to telomere

cellular localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

protein localization to organelle [inference]

protein localization to chromosome [inference]

protein localization to chromosome, telomeric region [inference]

establishment of protein localization to telomere

establishment of protein localization to chromosome [inference]

establishment of protein localization to telomere

establishment of protein localization to organelle [inference]

establishment of protein localization to chromosome [inference]

establishment of protein localization to telomere

establishment of protein localization [inference]

establishment of protein localization to organelle [inference]

establishment of protein localization to chromosome [inference]

establishment of protein localization to telomere

biological regulation [inference]

regulation of biological process [inference]

regulation of metabolic process [inference]

regulation of biosynthetic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

positive regulation of transcription, DNA-templated

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

positive regulation of transcription, DNA-templated

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of nitrogen compound metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of macromolecule metabolic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

positive regulation of transcription, DNA-templated

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of primary metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of signaling [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of cell cycle checkpoint [inference]

regulation of DNA damage checkpoint

positive regulation of biological process [inference]

positive regulation of metabolic process [inference]

positive regulation of biosynthetic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of macromolecule metabolic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nitrogen compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle

negative regulation of biological process [inference]

negative regulation of cellular process [inference]

negative regulation of cell population proliferation [inference]

negative regulation of epithelial cell proliferation [inference]

negative regulation of mammary gland epithelial cell proliferation

negative regulation of multicellular organismal process [inference]

negative regulation of mammary gland epithelial cell proliferation

regulation of response to stimulus [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of cell cycle checkpoint [inference]

regulation of DNA damage checkpoint

regulation of response to stress [inference]

regulation of cellular response to stress [inference]

regulation of DNA damage checkpoint

regulation of cellular process [inference]

signal transduction [inference]

intracellular signal transduction [inference]

signal transduction in response to DNA damage [inference]

DNA damage response, signal transduction by p53 class mediator [inference]

DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator

DNA damage response, signal transduction resulting in transcription [inference]

DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator

signal transduction by p53 class mediator [inference]

DNA damage response, signal transduction by p53 class mediator [inference]

DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator

intrinsic apoptotic signaling pathway by p53 class mediator [inference]

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

intrinsic apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway in response to DNA damage [inference]

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

intrinsic apoptotic signaling pathway by p53 class mediator [inference]

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway [inference]

intrinsic apoptotic signaling pathway in response to DNA damage [inference]

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

intrinsic apoptotic signaling pathway by p53 class mediator [inference]

intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator

regulation of cell communication [inference]

regulation of signal transduction [inference]

regulation of intracellular signal transduction [inference]

regulation of cell cycle checkpoint [inference]

regulation of DNA damage checkpoint

regulation of cellular metabolic process [inference]

regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of cellular biosynthetic process [inference]

regulation of macromolecule biosynthetic process [inference]

regulation of gene expression [inference]

regulation of transcription, DNA-templated

positive regulation of transcription, DNA-templated

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of RNA biosynthetic process [inference]

regulation of transcription, DNA-templated

positive regulation of transcription, DNA-templated

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

regulation of cell population proliferation [inference]

negative regulation of cell population proliferation [inference]

negative regulation of epithelial cell proliferation [inference]

negative regulation of mammary gland epithelial cell proliferation

regulation of epithelial cell proliferation [inference]

regulation of mammary gland epithelial cell proliferation [inference]

negative regulation of mammary gland epithelial cell proliferation

negative regulation of epithelial cell proliferation [inference]

negative regulation of mammary gland epithelial cell proliferation

positive regulation of cellular process [inference]

positive regulation of cellular metabolic process [inference]

positive regulation of cellular biosynthetic process [inference]

positive regulation of macromolecule biosynthetic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of nucleobase-containing compound metabolic process [inference]

positive regulation of RNA metabolic process [inference]

positive regulation of RNA biosynthetic process [inference]

positive regulation of transcription, DNA-templated

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle

negative regulation of cellular process [inference]

negative regulation of cell population proliferation [inference]

negative regulation of epithelial cell proliferation [inference]

negative regulation of mammary gland epithelial cell proliferation

regulation of cell division [inference]

regulation of cytokinesis

regulation of cell cycle [inference]

regulation of mitotic cell cycle [inference]

positive regulation of mitotic cell cycle

regulation of cell cycle process [inference]

regulation of cytokinesis

regulation of cell cycle phase transition [inference]

regulation of cell cycle checkpoint [inference]

regulation of DNA damage checkpoint

positive regulation of cell cycle [inference]

positive regulation of mitotic cell cycle

regulation of cellular response to stress [inference]

regulation of DNA damage checkpoint

regulation of multicellular organismal process [inference]

negative regulation of multicellular organismal process [inference]

negative regulation of mammary gland epithelial cell proliferation

Displaying entries **1 - 5** of 15 in total

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GO Term	Evidence Code	PMID
nuclear ubiquitin ligase complex	IDA	14636569
chromosome, telomeric region	IDA	21076401
lateral element	IDA	9774970
nucleus	NAS	19369211
nucleus	IDA	14636569 17286961 26833090 9560268 9774970

GO Hierarchy

cellular component

protein-containing complex

nuclear protein-containing complex [inference]

nuclear ubiquitin ligase complex

intracellular protein-containing complex [inference]

ubiquitin ligase complex [inference]

nuclear ubiquitin ligase complex

BRCA2-MAGE-D1 complex

catalytic complex [inference]

transferase complex [inference]

ubiquitin ligase complex [inference]

nuclear ubiquitin ligase complex

DNA repair complex

cellular anatomical entity [inference]

microtubule organizing center [inference]

centrosome

cytosol

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

intracellular membrane-bounded organelle [inference]

nucleus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

nucleus

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

secretory vesicle [inference]

secretory granule

chromosomal region [inference]

chromosome, telomeric region

Displaying entries **1 - 5** of 9 in total

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GO Term	Evidence Code	PMID
protease binding	IPI	15314155
single-stranded DNA binding	IDA	20729832
histone acetyltransferase activity	IDA	9824164
protein binding	IDA	9774970
protein binding	IPI	10373512 10551859 11597317 12242698 12442171 15115758 15800615 15930293 15967112 16099937 16205630 16275750 17420451 17515903 17515904 17541404 18212739 18264088 19303847 19369211 19423707 19609323 19628690 20421506 20729832 20729859 21399666 21601571 21719596 22116401 22193777 22293751 24013206 24141787 24485656 24981860 25282148 25585578 26833090 28319063 30410870 31242413 33961781 34591612 39009827 9560268 9774970

GO Hierarchy

molecular function

catalytic activity [inference]

transferase activity [inference]

acyltransferase activity [inference]

acyltransferase activity, transferring groups other than amino-acyl groups [inference]

acetyltransferase activity [inference]

N-acetyltransferase activity [inference]

peptide N-acetyltransferase activity [inference]

peptide-lysine-N-acetyltransferase activity [inference]

histone acetyltransferase activity

N-acyltransferase activity [inference]

N-acetyltransferase activity [inference]

peptide N-acetyltransferase activity [inference]

peptide-lysine-N-acetyltransferase activity [inference]

histone acetyltransferase activity

catalytic activity, acting on a protein [inference]

peptide-lysine-N-acetyltransferase activity [inference]

histone acetyltransferase activity

histone modifying activity [inference]

histone acetyltransferase activity

binding [inference]

protein binding

cytoskeletal protein binding [inference]

tubulin binding [inference]

gamma-tubulin binding

enzyme binding [inference]

protease binding

identical protein binding

organic cyclic compound binding [inference]

nucleic acid binding [inference]

DNA binding [inference]

single-stranded DNA binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Breast cancer 2 susceptibility protein

Functional Category

E: Amino acid transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying **all 2** entries
Gene Ontology
DNA recombination
DNA repair

Displaying **all 7** entries
InterPro
BRCA2 helical domain superfamily
BRCA2 repeat
BRCA2, OB1
Breast cancer type 2 susceptibility protein, helical domain
Breast cancer type 2 susceptibility protein
Nucleic acid-binding, OB-fold
Tower domain

Disease

Disease Ontology

Displaying entries **1 - 10** of 17 in total

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DO ID	Disease Name	Source
DOID:0050902	medulloblastoma	Alliance of Genome Resources
DOID:0060074	ductal carcinoma in situ	Alliance of Genome Resources
DOID:0111089	Fanconi anemia complementation group D1	Alliance of Genome Resources
DOID:10283	prostate cancer	Alliance of Genome Resources
DOID:13636	Fanconi anemia	Alliance of Genome Resources
DOID:1380	endometrial cancer	Alliance of Genome Resources
DOID:1612	breast cancer	Alliance of Genome Resources
DOID:1793	pancreatic cancer	Alliance of Genome Resources
DOID:1909	melanoma	Alliance of Genome Resources
DOID:2154	nephroblastoma	Alliance of Genome Resources

GlyTouCan

GlyComb

GlycoPOST

UniCarb-DR

LM-GlycoRepo

All Resources

Other Information

Tools

Search Tools

Guidelines

Summary

External Links

Annotation

OrthoDB (Group)

International Collaboration

Acknowledgements