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sorting nexin 2

Summary

Gene Symbol

Snx2

Organism

Mus musculus (house mouse)

External Links

NCBI Gene

67804

PubChem

67804

Alliance of Genome Resources

MGI:1915054

Annotation

Keyword

Acetylation
Cell projection
Endosome
Lipid-binding
Membrane
Phosphoprotein
Protein transport
Reference proteome

Proteins

Displaying 1 entry
UniProt	Protein Name
Q9CWK8

Annotation information from UniProt.

Gene Ontology (GO)

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GO Term	Evidence Code	PMID
intracellular protein transport	IEA
early endosome to Golgi transport	IBA
retrograde transport, endosome to Golgi	ISS
retrograde transport, endosome to Golgi	ISO
lamellipodium morphogenesis	ISS

GO Hierarchy

biological process

cellular process [inference]

vesicle-mediated transport [inference]

endosomal transport [inference]

retrograde transport, endosome to Golgi

early endosome to Golgi transport

Golgi vesicle transport [inference]

early endosome to Golgi transport

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport

endosomal transport [inference]

retrograde transport, endosome to Golgi

early endosome to Golgi transport

cytosolic transport [inference]

retrograde transport, endosome to Golgi

early endosome to Golgi transport

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

cellular component organization or biogenesis [inference]

cellular component organization [inference]

cell projection organization [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

lamellipodium morphogenesis

plasma membrane bounded cell projection organization [inference]

lamellipodium organization [inference]

lamellipodium morphogenesis

developmental process [inference]

anatomical structure morphogenesis [inference]

cellular anatomical entity morphogenesis [inference]

cell projection morphogenesis [inference]

plasma membrane bounded cell projection morphogenesis [inference]

lamellipodium morphogenesis

localization [inference]

macromolecule localization [inference]

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

establishment of localization [inference]

transport [inference]

vesicle-mediated transport [inference]

endosomal transport [inference]

retrograde transport, endosome to Golgi

early endosome to Golgi transport

Golgi vesicle transport [inference]

early endosome to Golgi transport

intracellular transport [inference]

intracellular protein transport

endosomal transport [inference]

retrograde transport, endosome to Golgi

early endosome to Golgi transport

cytosolic transport [inference]

retrograde transport, endosome to Golgi

early endosome to Golgi transport

organic substance transport [inference]

protein transport [inference]

intracellular protein transport

nitrogen compound transport [inference]

protein transport [inference]

intracellular protein transport

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

establishment of localization in cell [inference]

intracellular transport [inference]

intracellular protein transport

endosomal transport [inference]

retrograde transport, endosome to Golgi

early endosome to Golgi transport

cytosolic transport [inference]

retrograde transport, endosome to Golgi

early endosome to Golgi transport

cellular localization [inference]

intracellular transport [inference]

intracellular protein transport

endosomal transport [inference]

retrograde transport, endosome to Golgi

early endosome to Golgi transport

cytosolic transport [inference]

retrograde transport, endosome to Golgi

early endosome to Golgi transport

cellular macromolecule localization [inference]

protein localization [inference]

establishment of protein localization [inference]

protein transport [inference]

intracellular protein transport

Displaying entries **1 - 5** of 17 in total

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GO Term	Evidence Code	PMID
cytoplasm	ISO
lysosome	ISO
lysosome	IEA
endosome	ISO
endosome	IBA

GO Hierarchy

cellular component

protein-containing complex

membrane protein complex [inference]

cellular anatomical entity [inference]

membrane

organelle membrane [inference]

vesicle membrane [inference]

cytoplasmic vesicle membrane [inference]

endosome membrane

early endosome membrane

bounding membrane of organelle [inference]

endosome membrane

early endosome membrane

cell projection [inference]

plasma membrane bounded cell projection [inference]

lamellipodium

organelle [inference]

membrane-bounded organelle [inference]

vesicle [inference]

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

intracellular organelle [inference]

intracellular membrane-bounded organelle [inference]

vacuole [inference]

lytic vacuole [inference]

lysosome

intracellular vesicle [inference]

cytoplasmic vesicle [inference]

endosome

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GO Term	Evidence Code	PMID
epidermal growth factor receptor binding	ISO
epidermal growth factor receptor binding	IEA
insulin receptor binding	ISO
insulin receptor binding	IEA
phosphatidylinositol binding	IBA

GO Hierarchy

molecular function

binding [inference]

protein binding [inference]

signaling receptor binding [inference]

insulin receptor binding

growth factor receptor binding [inference]

epidermal growth factor receptor binding

identical protein binding

protein homodimerization activity

protein dimerization activity [inference]

lipid binding [inference]

phospholipid binding [inference]

phosphatidylinositol binding

Gene Ontology information from NCBI Gene and UniProt.

OrthoDB (Group)

Group level

Eukaryota

Group Name

Sorting nexin

Functional Category

G: Carbohydrate transport and metabolism
M: Cell wall/membrane/envelope biogenesis
T: Signal transduction mechanisms

Displaying 1 entry
Gene Ontology
phosphatidylinositol binding

Displaying **all 3** entries
InterPro
AH/BAR domain superfamily
PX domain superfamily
Phox homology

Ortholog

Displaying entries **1 - 10** of 90 in total

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Species	Gene ID	Alliance of Genome Resources	Orthologous MAtrix
Homo sapiens	6643	Xenbase:XB-GENE-5791488	HUMAN80454
Saccharomyces cerevisiae S288C	56440	SGD:S000005595
Xenopus tropicalis	67804	Xenbase:XB-GENE-5791488
Rattus norvegicus	291464		RATNO13346
Pan troglodytes	462022		PANTR36003
Canis lupus familiaris	474657		CANLF02041
Bos taurus	509769		BOVIN33095
Macaca mulatta	700507		MACMU39126
Macaca mulatta	700621		MACMU39126
Monodelphis domestica	100014288		MONDO29445