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Genes / Proteins / Lipids Glycans / Glycoconjugates Glycomes Pathways / Interactions / Diseases / Organisms
stromal interaction molecule 1
Summary
- Gene Symbol
-
- STIM1
- Organism
- Homo sapiens (human)
Annotation
- Keyword
-
- 3D-structure
- Alternative splicing
- Calcium transport
- Cell membrane
- Coiled coil
- Cytoskeleton
- Disease variant
- Endoplasmic reticulum
- Glycoprotein
- Metal-binding
- Microtubule
- Phosphoprotein
- Proteomics identification
- Reference proteome
- Sarcoplasmic reticulum
- Signal
- Transmembrane helix
- Proteins
Gene Ontology (GO)
| GO Term | Evidence Code | PMID |
|---|---|---|
| positive regulation of adenylate cyclase activity | ||
| positive regulation of angiogenesis | ||
| regulation of store-operated calcium entry | ||
| detection of calcium ion | ||
| intracellular calcium ion homeostasis |
GO Hierarchy
biological process
biological regulation [inference]
regulation of biological process [inference]
regulation of localization [inference]
regulation of transport [inference]
regulation of transmembrane transport [inference]
regulation of monoatomic ion transport [inference]
positive regulation of transport [inference]
positive regulation of biological process [inference]
regulation of cellular process [inference]
regulation of molecular function [inference]
| GO Term | Evidence Code | PMID |
|---|---|---|
| microtubule | ||
| sarcoplasmic reticulum membrane | ||
| plasma membrane raft | ||
| cortical endoplasmic reticulum | ||
| endoplasmic reticulum membrane |
GO Hierarchy
| GO Term | Evidence Code | PMID |
|---|---|---|
| protein binding | ||
| calcium channel regulator activity | ||
| protease binding | ||
| identical protein binding | ||
| calcium ion binding |
GO Hierarchy
OrthoDB (Group)
- Group level
- Eukaryota
- Group Name
- Stromal interaction molecule
- Functional Category
-
- E: Amino acid transport and metabolism
- G: Carbohydrate transport and metabolism
- T: Signal transduction mechanisms
Disease
- Disease Ontology
| DO ID | Disease Name | Source |
|---|---|---|
| DOID:0060354 | Stormorken syndrome | |
| DOID:0080089 | tubular aggregate myopathy 1 | |
| DOID:0111970 | immunodeficiency 10 | |
| DOID:10534 | stomach cancer | |
| DOID:11984 | hypertrophic cardiomyopathy | |
| DOID:12387 | nephrogenic diabetes insipidus | |
| DOID:12930 | dilated cardiomyopathy | |
| DOID:1324 | lung cancer | |
| DOID:3908 | lung non-small cell carcinoma | |
| DOID:684 | hepatocellular carcinoma |
Ortholog
| Species | Gene ID | OrthoDB | Alliance of Genome Resources | Orthologous MAtrix |
|---|---|---|---|---|
| 20866 | MGI:107476 | MOUSE56675 | ||
| 32556 | FB:FBgn0045073 | |||
| 175201 | WB:WBGene00021910 | |||
| 361618 | RGD:1306831 | RATNO16700 | ||
| 403095 | Xenbase:XB-GENE-947969 | |||
| 450973 | 9598_0:00305b | PANTR02088 | ||
| 534816 | BOVIN07117 | |||
| 556360 | ZFIN:ZDB-GENE-060503-914 | DANRE09214 | ||
| 608643 | CANLF08323 | |||
| 717963 | MACMU09649 |
